BindingDB logo
myBDB logout

PubMed code 19692250

Compile data set for download or QSAR
Found 52 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304245
PNG
(6,7-Dimethoxy-3-[4-(pyrrolidin-1-ylmethyl)-phenyl]...)
Show SMILES COc1cc2occ(-c3ccc(cc3)N3CCCC3)c(=O)c2cc1OC
Show InChI InChI=1S/C21H21NO4/c1-24-19-11-16-18(12-20(19)25-2)26-13-17(21(16)23)14-5-7-15(8-6-14)22-9-3-4-10-22/h5-8,11-13H,3-4,9-10H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM8960
PNG
((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Show SMILES COc1cc2CC(CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC
Show InChI InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304246
PNG
(6,7-Dimethoxy-2-[4-(piperidin-1-ylmethyl)-phenyl]-...)
Show SMILES COc1cc2oc(cc(=O)c2cc1OC)-c1ccc(cc1)N1CCCCC1
Show InChI InChI=1S/C22H23NO4/c1-25-21-12-17-18(24)13-19(27-20(17)14-22(21)26-2)15-6-8-16(9-7-15)23-10-4-3-5-11-23/h6-9,12-14H,3-5,10-11H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 34n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304249
PNG
((E)-1-(2-Hydroxy-4,5-dimethoxyphenyl)-3-[4-(pyrrol...)
Show SMILES COc1cc(O)c(cc1OC)C(=O)\C=C\c1ccc(cc1)N1CCCC1
Show InChI InChI=1S/C21H23NO4/c1-25-20-13-17(19(24)14-21(20)26-2)18(23)10-7-15-5-8-16(9-6-15)22-11-3-4-12-22/h5-10,13-14,24H,3-4,11-12H2,1-2H3/b10-7+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 37n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304247
PNG
((E)-1-(2-Hydroxy-4,5-dimethoxyphenyl)-3-[3-(pyrrol...)
Show SMILES COc1cc(O)c(cc1OC)C(=O)\C=C\c1cccc(c1)N1CCCC1
Show InChI InChI=1S/C21H23NO4/c1-25-20-13-17(19(24)14-21(20)26-2)18(23)9-8-15-6-5-7-16(12-15)22-10-3-4-11-22/h5-9,12-14,24H,3-4,10-11H2,1-2H3/b9-8+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 47n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304248
PNG
(6,7-Dimethoxy-2-[4-(pyrrolidin-1-ylmethyl)-phenyl]...)
Show SMILES COc1cc2oc(cc(=O)c2cc1OC)-c1ccc(cc1)N1CCCC1
Show InChI InChI=1S/C21H21NO4/c1-24-20-11-16-17(23)12-18(26-19(16)13-21(20)25-2)14-5-7-15(8-6-14)22-9-3-4-10-22/h5-8,11-13H,3-4,9-10H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 55n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304250
PNG
(6,7-Dimethoxy-3-[4-(piperidin-1-ylmethyl)-phenyl]-...)
Show SMILES COc1cc2occ(-c3ccc(cc3)N3CCCCC3)c(=O)c2cc1OC
Show InChI InChI=1S/C22H23NO4/c1-25-20-12-17-19(13-21(20)26-2)27-14-18(22(17)24)15-6-8-16(9-7-15)23-10-4-3-5-11-23/h6-9,12-14H,3-5,10-11H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 68n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304227
PNG
(6,7-Dimethoxy-3-[3-(pyrrolidin-1-ylmethyl)-phenyl]...)
Show SMILES COc1cc2occ(-c3cccc(c3)N3CCCC3)c(=O)c2cc1OC
Show InChI InChI=1S/C21H21NO4/c1-24-19-11-16-18(12-20(19)25-2)26-13-17(21(16)23)14-6-5-7-15(10-14)22-8-3-4-9-22/h5-7,10-13H,3-4,8-9H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 70n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304228
PNG
((E)-3-{4-[(Diethylamino)-methyl]-phenyl}-1-(2-hydr...)
Show SMILES CCN(CC)c1ccc(\C=C\C(=O)c2cc(OC)c(OC)cc2O)cc1
Show InChI InChI=1S/C21H25NO4/c1-5-22(6-2)16-10-7-15(8-11-16)9-12-18(23)17-13-20(25-3)21(26-4)14-19(17)24/h7-14,24H,5-6H2,1-4H3/b12-9+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 103n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304229
PNG
((E)-1-(2-Hydroxy-4,5-dimethoxyphenyl)-3-[4-(piperi...)
Show SMILES COc1cc(O)c(cc1OC)C(=O)\C=C\c1ccc(cc1)N1CCCCC1
Show InChI InChI=1S/C22H25NO4/c1-26-21-14-18(20(25)15-22(21)27-2)19(24)11-8-16-6-9-17(10-7-16)23-12-4-3-5-13-23/h6-11,14-15,25H,3-5,12-13H2,1-2H3/b11-8+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 122n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304230
PNG
((E)-3-{4-[(Ethylmethylamino)-methyl]-phenyl}-1-(2-...)
Show SMILES CCN(C)c1ccc(\C=C\C(=O)c2cc(OC)c(OC)cc2O)cc1
Show InChI InChI=1S/C20H23NO4/c1-5-21(2)15-9-6-14(7-10-15)8-11-17(22)16-12-19(24-3)20(25-4)13-18(16)23/h6-13,23H,5H2,1-4H3/b11-8+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 126n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304231
PNG
(6,7-Dimethoxy-3-{4-[(ethylmethylamino)-methyl]-phe...)
Show SMILES CCN(C)c1ccc(cc1)-c1coc2cc(OC)c(OC)cc2c1=O
Show InChI InChI=1S/C20H21NO4/c1-5-21(2)14-8-6-13(7-9-14)16-12-25-17-11-19(24-4)18(23-3)10-15(17)20(16)22/h6-12H,5H2,1-4H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 171n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304232
PNG
(6,7-Dimethoxy-2-[4-(piperidin-1-ylmethyl)-phenyl]-...)
Show SMILES COc1cc2OC(CC(=O)c2cc1OC)c1ccc(cc1)N1CCCCC1
Show InChI InChI=1S/C22H25NO4/c1-25-21-12-17-18(24)13-19(27-20(17)14-22(21)26-2)15-6-8-16(9-7-15)23-10-4-3-5-11-23/h6-9,12,14,19H,3-5,10-11,13H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 248n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304233
PNG
(6,7-Dimethoxy-2-{4-[(ethylmethylamino)-methyl)-phe...)
Show SMILES CCN(C)c1ccc(cc1)-c1cc(=O)c2cc(OC)c(OC)cc2o1
Show InChI InChI=1S/C20H21NO4/c1-5-21(2)14-8-6-13(7-9-14)17-11-16(22)15-10-19(23-3)20(24-4)12-18(15)25-17/h6-12H,5H2,1-4H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 336n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304234
PNG
(3-{3-[(Diethylamino)-methyl]-phenyl}-6,7-dimethoxy...)
Show SMILES CCN(CC)c1cccc(c1)-c1coc2cc(OC)c(OC)cc2c1=O
Show InChI InChI=1S/C21H23NO4/c1-5-22(6-2)15-9-7-8-14(10-15)17-13-26-18-12-20(25-4)19(24-3)11-16(18)21(17)23/h7-13H,5-6H2,1-4H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 560n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304235
PNG
(3-{4-[(Diethylamino)-methyl]-phenyl}-6,7-dimethoxy...)
Show SMILES CCN(CC)c1ccc(cc1)-c1coc2cc(OC)c(OC)cc2c1=O
Show InChI InChI=1S/C21H23NO4/c1-5-22(6-2)15-9-7-14(8-10-15)17-13-26-18-12-20(25-4)19(24-3)11-16(18)21(17)23/h7-13H,5-6H2,1-4H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 599n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304236
PNG
(2-[4-(Diethylamino-methyl)-phenyl]-6,7-dimethoxy-4...)
Show SMILES CCN(CC)c1ccc(cc1)-c1cc(=O)c2cc(OC)c(OC)cc2o1
Show InChI InChI=1S/C21H23NO4/c1-5-22(6-2)15-9-7-14(8-10-15)18-12-17(23)16-11-20(24-3)21(25-4)13-19(16)26-18/h7-13H,5-6H2,1-4H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 639n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304237
PNG
(6,7-Dimethoxy-2-[3-(pyrrolidin-1-ylmethyl)-phenyl]...)
Show SMILES COc1cc2oc(cc(=O)c2cc1OC)-c1cccc(c1)N1CCCC1
Show InChI InChI=1S/C21H21NO4/c1-24-20-11-16-17(23)12-18(26-19(16)13-21(20)25-2)14-6-5-7-15(10-14)22-8-3-4-9-22/h5-7,10-13H,3-4,8-9H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 704n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304238
PNG
(6,7-Dimethoxy-2-[4-(pyrrolidin-1-ylmethyl)-phenyl]...)
Show SMILES COc1cc2OC(CC(=O)c2cc1OC)c1ccc(cc1)N1CCCC1
Show InChI InChI=1S/C21H23NO4/c1-24-20-11-16-17(23)12-18(26-19(16)13-21(20)25-2)14-5-7-15(8-6-14)22-9-3-4-10-22/h5-8,11,13,18H,3-4,9-10,12H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.24E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304239
PNG
((E)-3-{3-[(Diethylamino)-methyl]-phenyl}-1-(2-hydr...)
Show SMILES CCN(CC)c1cccc(\C=C\C(=O)c2cc(OC)c(OC)cc2O)c1
Show InChI InChI=1S/C21H25NO4/c1-5-22(6-2)16-9-7-8-15(12-16)10-11-18(23)17-13-20(25-3)21(26-4)14-19(17)24/h7-14,24H,5-6H2,1-4H3/b11-10+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.61E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM10620
PNG
((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Show SMILES CCN(C)C(=O)Oc1cccc(c1)[C@H](C)N(C)C
Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1
Reactome pathway
KEGG

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.66E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM10620
PNG
((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Show SMILES CCN(C)C(=O)Oc1cccc(c1)[C@H](C)N(C)C
Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.25E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM8960
PNG
((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Show SMILES COc1cc2CC(CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC
Show InChI InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 4.67E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304240
PNG
(6,7-Dimethoxy-2-{4-[(ethylmethylamino)-methyl]-phe...)
Show SMILES CCN(C)c1ccc(cc1)C1CC(=O)c2cc(OC)c(OC)cc2O1
Show InChI InChI=1S/C20H23NO4/c1-5-21(2)14-8-6-13(7-9-14)17-11-16(22)15-10-19(23-3)20(24-4)12-18(15)25-17/h6-10,12,17H,5,11H2,1-4H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.67E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304241
PNG
(2-{4-[(Diethylamino)-methyl]-phenyl}-6,7-dimethoxy...)
Show SMILES CCN(CC)c1ccc(cc1)C1CC(=O)c2cc(OC)c(OC)cc2O1
Show InChI InChI=1S/C21H25NO4/c1-5-22(6-2)15-9-7-14(8-10-15)18-12-17(23)16-11-20(24-3)21(25-4)13-19(16)26-18/h7-11,13,18H,5-6,12H2,1-4H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.97E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304242
PNG
(6,7-Dimethoxy-2-[3-(pyrrolidin-1-ylmethyl)-phenyl]...)
Show SMILES COc1cc2OC(CC(=O)c2cc1OC)c1cccc(c1)N1CCCC1
Show InChI InChI=1S/C21H23NO4/c1-24-20-11-16-17(23)12-18(26-19(16)13-21(20)25-2)14-6-5-7-15(10-14)22-8-3-4-9-22/h5-7,10-11,13,18H,3-4,8-9,12H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.36E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304243
PNG
(2-{3-[(Diethylamino)-methyl]-phenyl}-6,7-dimethoxy...)
Show SMILES CCN(CC)c1cccc(c1)-c1cc(=O)c2cc(OC)c(OC)cc2o1
Show InChI InChI=1S/C21H23NO4/c1-5-22(6-2)15-9-7-8-14(10-15)18-12-17(23)16-11-20(24-3)21(25-4)13-19(16)26-18/h7-13H,5-6H2,1-4H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.99E+3n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304245
PNG
(6,7-Dimethoxy-3-[4-(pyrrolidin-1-ylmethyl)-phenyl]...)
Show SMILES COc1cc2occ(-c3ccc(cc3)N3CCCC3)c(=O)c2cc1OC
Show InChI InChI=1S/C21H21NO4/c1-24-19-11-16-18(12-20(19)25-2)26-13-17(21(16)23)14-5-7-15(8-6-14)22-9-3-4-10-22/h5-8,11-13H,3-4,9-10H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.83E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304232
PNG
(6,7-Dimethoxy-2-[4-(piperidin-1-ylmethyl)-phenyl]-...)
Show SMILES COc1cc2OC(CC(=O)c2cc1OC)c1ccc(cc1)N1CCCCC1
Show InChI InChI=1S/C22H25NO4/c1-25-21-12-17-18(24)13-19(27-20(17)14-22(21)26-2)15-6-8-16(9-7-15)23-10-4-3-5-11-23/h6-9,12,14,19H,3-5,10-11,13H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.80E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304231
PNG
(6,7-Dimethoxy-3-{4-[(ethylmethylamino)-methyl]-phe...)
Show SMILES CCN(C)c1ccc(cc1)-c1coc2cc(OC)c(OC)cc2c1=O
Show InChI InChI=1S/C20H21NO4/c1-5-21(2)14-8-6-13(7-9-14)16-12-25-17-11-19(24-4)18(23-3)10-15(17)20(16)22/h6-12H,5H2,1-4H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.10E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304236
PNG
(2-[4-(Diethylamino-methyl)-phenyl]-6,7-dimethoxy-4...)
Show SMILES CCN(CC)c1ccc(cc1)-c1cc(=O)c2cc(OC)c(OC)cc2o1
Show InChI InChI=1S/C21H23NO4/c1-5-22(6-2)15-9-7-14(8-10-15)18-12-17(23)16-11-20(24-3)21(25-4)13-19(16)26-18/h7-13H,5-6H2,1-4H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.46E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304238
PNG
(6,7-Dimethoxy-2-[4-(pyrrolidin-1-ylmethyl)-phenyl]...)
Show SMILES COc1cc2OC(CC(=O)c2cc1OC)c1ccc(cc1)N1CCCC1
Show InChI InChI=1S/C21H23NO4/c1-24-20-11-16-17(23)12-18(26-19(16)13-21(20)25-2)14-5-7-15(8-6-14)22-9-3-4-10-22/h5-8,11,13,18H,3-4,9-10,12H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.82E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304246
PNG
(6,7-Dimethoxy-2-[4-(piperidin-1-ylmethyl)-phenyl]-...)
Show SMILES COc1cc2oc(cc(=O)c2cc1OC)-c1ccc(cc1)N1CCCCC1
Show InChI InChI=1S/C22H23NO4/c1-25-21-12-17-18(24)13-19(27-20(17)14-22(21)26-2)15-6-8-16(9-7-15)23-10-4-3-5-11-23/h6-9,12-14H,3-5,10-11H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.52E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304247
PNG
((E)-1-(2-Hydroxy-4,5-dimethoxyphenyl)-3-[3-(pyrrol...)
Show SMILES COc1cc(O)c(cc1OC)C(=O)\C=C\c1cccc(c1)N1CCCC1
Show InChI InChI=1S/C21H23NO4/c1-25-20-13-17(19(24)14-21(20)26-2)18(23)9-8-15-6-5-7-16(12-15)22-10-3-4-11-22/h5-9,12-14,24H,3-4,10-11H2,1-2H3/b9-8+
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.73E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304248
PNG
(6,7-Dimethoxy-2-[4-(pyrrolidin-1-ylmethyl)-phenyl]...)
Show SMILES COc1cc2oc(cc(=O)c2cc1OC)-c1ccc(cc1)N1CCCC1
Show InChI InChI=1S/C21H21NO4/c1-24-20-11-16-17(23)12-18(26-19(16)13-21(20)25-2)14-5-7-15(8-6-14)22-9-3-4-10-22/h5-8,11-13H,3-4,9-10H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.97E+4n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304234
PNG
(3-{3-[(Diethylamino)-methyl]-phenyl}-6,7-dimethoxy...)
Show SMILES CCN(CC)c1cccc(c1)-c1coc2cc(OC)c(OC)cc2c1=O
Show InChI InChI=1S/C21H23NO4/c1-5-22(6-2)15-9-7-8-14(10-15)17-13-26-18-12-20(25-4)19(24-3)11-16(18)21(17)23/h7-13H,5-6H2,1-4H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304244
PNG
(2-{3-[(Diethylamino)-methyl]-phenyl}-6,7-dimethoxy...)
Show SMILES CCN(CC)c1cccc(c1)C1CC(=O)c2cc(OC)c(OC)cc2O1
Show InChI InChI=1S/C21H25NO4/c1-5-22(6-2)15-9-7-8-14(10-15)18-12-17(23)16-11-20(24-3)21(25-4)13-19(16)26-18/h7-11,13,18H,5-6,12H2,1-4H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304250
PNG
(6,7-Dimethoxy-3-[4-(piperidin-1-ylmethyl)-phenyl]-...)
Show SMILES COc1cc2occ(-c3ccc(cc3)N3CCCCC3)c(=O)c2cc1OC
Show InChI InChI=1S/C22H23NO4/c1-25-20-12-17-19(13-21(20)26-2)27-14-18(22(17)24)15-6-8-16(9-7-15)23-10-4-3-5-11-23/h6-9,12-14H,3-5,10-11H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304233
PNG
(6,7-Dimethoxy-2-{4-[(ethylmethylamino)-methyl)-phe...)
Show SMILES CCN(C)c1ccc(cc1)-c1cc(=O)c2cc(OC)c(OC)cc2o1
Show InChI InChI=1S/C20H21NO4/c1-5-21(2)14-8-6-13(7-9-14)17-11-16(22)15-10-19(23-3)20(24-4)12-18(15)25-17/h6-12H,5H2,1-4H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304239
PNG
((E)-3-{3-[(Diethylamino)-methyl]-phenyl}-1-(2-hydr...)
Show SMILES CCN(CC)c1cccc(\C=C\C(=O)c2cc(OC)c(OC)cc2O)c1
Show InChI InChI=1S/C21H25NO4/c1-5-22(6-2)16-9-7-8-15(12-16)10-11-18(23)17-13-20(25-3)21(26-4)14-19(17)24/h7-14,24H,5-6H2,1-4H3/b11-10+
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304230
PNG
((E)-3-{4-[(Ethylmethylamino)-methyl]-phenyl}-1-(2-...)
Show SMILES CCN(C)c1ccc(\C=C\C(=O)c2cc(OC)c(OC)cc2O)cc1
Show InChI InChI=1S/C20H23NO4/c1-5-21(2)15-9-6-14(7-10-15)8-11-17(22)16-12-19(24-3)20(25-4)13-18(16)23/h6-13,23H,5H2,1-4H3/b11-8+
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304249
PNG
((E)-1-(2-Hydroxy-4,5-dimethoxyphenyl)-3-[4-(pyrrol...)
Show SMILES COc1cc(O)c(cc1OC)C(=O)\C=C\c1ccc(cc1)N1CCCC1
Show InChI InChI=1S/C21H23NO4/c1-25-20-13-17(19(24)14-21(20)26-2)18(23)10-7-15-5-8-16(9-6-15)22-11-3-4-12-22/h5-10,13-14,24H,3-4,11-12H2,1-2H3/b10-7+
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304229
PNG
((E)-1-(2-Hydroxy-4,5-dimethoxyphenyl)-3-[4-(piperi...)
Show SMILES COc1cc(O)c(cc1OC)C(=O)\C=C\c1ccc(cc1)N1CCCCC1
Show InChI InChI=1S/C22H25NO4/c1-26-21-14-18(20(25)15-22(21)27-2)19(24)11-8-16-6-9-17(10-7-16)23-12-4-3-5-13-23/h6-11,14-15,25H,3-5,12-13H2,1-2H3/b11-8+
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304242
PNG
(6,7-Dimethoxy-2-[3-(pyrrolidin-1-ylmethyl)-phenyl]...)
Show SMILES COc1cc2OC(CC(=O)c2cc1OC)c1cccc(c1)N1CCCC1
Show InChI InChI=1S/C21H23NO4/c1-24-20-11-16-17(23)12-18(26-19(16)13-21(20)25-2)14-6-5-7-15(10-14)22-8-3-4-9-22/h5-7,10-11,13,18H,3-4,8-9,12H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304241
PNG
(2-{4-[(Diethylamino)-methyl]-phenyl}-6,7-dimethoxy...)
Show SMILES CCN(CC)c1ccc(cc1)C1CC(=O)c2cc(OC)c(OC)cc2O1
Show InChI InChI=1S/C21H25NO4/c1-5-22(6-2)15-9-7-14(8-10-15)18-12-17(23)16-11-20(24-3)21(25-4)13-19(16)26-18/h7-11,13,18H,5-6,12H2,1-4H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304240
PNG
(6,7-Dimethoxy-2-{4-[(ethylmethylamino)-methyl]-phe...)
Show SMILES CCN(C)c1ccc(cc1)C1CC(=O)c2cc(OC)c(OC)cc2O1
Show InChI InChI=1S/C20H23NO4/c1-5-21(2)14-8-6-13(7-9-14)17-11-16(22)15-10-19(23-3)20(24-4)12-18(15)25-17/h6-10,12,17H,5,11H2,1-4H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304243
PNG
(2-{3-[(Diethylamino)-methyl]-phenyl}-6,7-dimethoxy...)
Show SMILES CCN(CC)c1cccc(c1)-c1cc(=O)c2cc(OC)c(OC)cc2o1
Show InChI InChI=1S/C21H23NO4/c1-5-22(6-2)15-9-7-8-14(10-15)18-12-17(23)16-11-20(24-3)21(25-4)13-19(16)26-18/h7-13H,5-6H2,1-4H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304235
PNG
(3-{4-[(Diethylamino)-methyl]-phenyl}-6,7-dimethoxy...)
Show SMILES CCN(CC)c1ccc(cc1)-c1coc2cc(OC)c(OC)cc2c1=O
Show InChI InChI=1S/C21H23NO4/c1-5-22(6-2)15-9-7-14(8-10-15)17-13-26-18-12-20(25-4)19(24-3)11-16(18)21(17)23/h7-13H,5-6H2,1-4H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304227
PNG
(6,7-Dimethoxy-3-[3-(pyrrolidin-1-ylmethyl)-phenyl]...)
Show SMILES COc1cc2occ(-c3cccc(c3)N3CCCC3)c(=O)c2cc1OC
Show InChI InChI=1S/C21H21NO4/c1-24-19-11-16-18(12-20(19)25-2)26-13-17(21(16)23)14-6-5-7-15(10-14)22-8-3-4-9-22/h5-7,10-13H,3-4,8-9H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304237
PNG
(6,7-Dimethoxy-2-[3-(pyrrolidin-1-ylmethyl)-phenyl]...)
Show SMILES COc1cc2oc(cc(=O)c2cc1OC)-c1cccc(c1)N1CCCC1
Show InChI InChI=1S/C21H21NO4/c1-24-20-11-16-17(23)12-18(26-19(16)13-21(20)25-2)14-6-5-7-15(10-14)22-8-3-4-9-22/h5-7,10-13H,3-4,8-9H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)


(Rattus norvegicus (rat))
BDBM50304228
PNG
((E)-3-{4-[(Diethylamino)-methyl]-phenyl}-1-(2-hydr...)
Show SMILES CCN(CC)c1ccc(\C=C\C(=O)c2cc(OC)c(OC)cc2O)cc1
Show InChI InChI=1S/C21H25NO4/c1-5-22(6-2)16-10-7-15(8-11-16)9-12-18(23)17-13-20(25-3)21(26-4)14-19(17)24/h7-14,24H,5-6H2,1-4H3/b12-9+
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of BChE in rat serum after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50304244
PNG
(2-{3-[(Diethylamino)-methyl]-phenyl}-6,7-dimethoxy...)
Show SMILES CCN(CC)c1cccc(c1)C1CC(=O)c2cc(OC)c(OC)cc2O1
Show InChI InChI=1S/C21H25NO4/c1-5-22(6-2)15-9-7-8-14(10-15)18-12-17(23)16-11-20(24-3)21(25-4)13-19(16)26-18/h7-11,13,18H,5-6,12H2,1-4H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.72E+5n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of AChE in rat cortex after 15 mins by modified Ellman's method


Bioorg Med Chem 17: 6692-8 (2009)


Article DOI: 10.1016/j.bmc.2009.07.072
BindingDB Entry DOI: 10.7270/Q29S1R4M
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%