BindingDB logo
myBDB logout

PubMed code 19733070

Compile data set for download or QSAR
Found 8 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Triosephosphate isomerase, glycosomal


(Trypanosoma cruzi)
BDBM50415047
PNG
(CHEMBL567076)
Show SMILES COC(=O)C1CC(=O)c2oc(=O)c3cc(O)c(O)c(O)c3c12
Show InChI InChI=1S/C14H10O8/c1-21-13(19)5-3-7(16)12-9(5)8-4(14(20)22-12)2-6(15)10(17)11(8)18/h2,5,15,17-18H,3H2,1H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.50E+3n/an/an/an/an/an/a



Universidad Aut£noma del Estado de Hidalgo

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi recombinant triosephosphate isomerase after 2 hrs


Bioorg Med Chem Lett 19: 5936-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.055
BindingDB Entry DOI: 10.7270/Q25T3MQF
More data for this
Ligand-Target Pair
Triosephosphate isomerase, glycosomal


(Trypanosoma cruzi)
BDBM50415048
PNG
(CHEMBL567077)
Show SMILES CCOC(=O)C1CC(=O)c2oc(=O)c3cc(O)c(O)c(O)c3c12
Show InChI InChI=1S/C15H12O8/c1-2-22-14(20)6-4-8(17)13-10(6)9-5(15(21)23-13)3-7(16)11(18)12(9)19/h3,6,16,18-19H,2,4H2,1H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.00E+3n/an/an/an/an/an/a



Universidad Aut£noma del Estado de Hidalgo

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi recombinant triosephosphate isomerase after 2 hrs


Bioorg Med Chem Lett 19: 5936-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.055
BindingDB Entry DOI: 10.7270/Q25T3MQF
More data for this
Ligand-Target Pair
Triosephosphate isomerase, glycosomal


(Trypanosoma cruzi)
BDBM50415049
PNG
(CHEMBL568338)
Show SMILES CCCCOC(=O)C1CC(=O)c2oc(=O)c3cc(O)c(O)c(O)c3c12
Show InChI InChI=1S/C17H16O8/c1-2-3-4-24-16(22)8-6-10(19)15-12(8)11-7(17(23)25-15)5-9(18)13(20)14(11)21/h5,8,18,20-21H,2-4,6H2,1H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



Universidad Aut£noma del Estado de Hidalgo

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi recombinant triosephosphate isomerase after 2 hrs


Bioorg Med Chem Lett 19: 5936-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.055
BindingDB Entry DOI: 10.7270/Q25T3MQF
More data for this
Ligand-Target Pair
Triosephosphate isomerase (TIM)


(Homo sapiens (Human))
BDBM50415049
PNG
(CHEMBL568338)
Show SMILES CCCCOC(=O)C1CC(=O)c2oc(=O)c3cc(O)c(O)c(O)c3c12
Show InChI InChI=1S/C17H16O8/c1-2-3-4-24-16(22)8-6-10(19)15-12(8)11-7(17(23)25-15)5-9(18)13(20)14(11)21/h5,8,18,20-21H,2-4,6H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Universidad Aut£noma del Estado de Hidalgo

Curated by ChEMBL


Assay Description
Inhibition of human recombinant triosephosphate isomerase after 2 hrs


Bioorg Med Chem Lett 19: 5936-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.055
BindingDB Entry DOI: 10.7270/Q25T3MQF
More data for this
Ligand-Target Pair
Triosephosphate isomerase (TIM)


(Homo sapiens (Human))
BDBM50415048
PNG
(CHEMBL567077)
Show SMILES CCOC(=O)C1CC(=O)c2oc(=O)c3cc(O)c(O)c(O)c3c12
Show InChI InChI=1S/C15H12O8/c1-2-22-14(20)6-4-8(17)13-10(6)9-5(15(21)23-13)3-7(16)11(18)12(9)19/h3,6,16,18-19H,2,4H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Universidad Aut£noma del Estado de Hidalgo

Curated by ChEMBL


Assay Description
Inhibition of human recombinant triosephosphate isomerase after 2 hrs


Bioorg Med Chem Lett 19: 5936-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.055
BindingDB Entry DOI: 10.7270/Q25T3MQF
More data for this
Ligand-Target Pair
Triosephosphate isomerase (TIM)


(Homo sapiens (Human))
BDBM50415047
PNG
(CHEMBL567076)
Show SMILES COC(=O)C1CC(=O)c2oc(=O)c3cc(O)c(O)c(O)c3c12
Show InChI InChI=1S/C14H10O8/c1-21-13(19)5-3-7(16)12-9(5)8-4(14(20)22-12)2-6(15)10(17)11(8)18/h2,5,15,17-18H,3H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Universidad Aut£noma del Estado de Hidalgo

Curated by ChEMBL


Assay Description
Inhibition of human recombinant triosephosphate isomerase after 2 hrs


Bioorg Med Chem Lett 19: 5936-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.055
BindingDB Entry DOI: 10.7270/Q25T3MQF
More data for this
Ligand-Target Pair
Triosephosphate isomerase, glycosomal


(Trypanosoma cruzi)
BDBM50415050
PNG
(CHEMBL567497)
Show SMILES COC(=O)C1CC(=O)c2oc(=O)c3cc(O)c(OC)c(OC)c3c12
Show InChI InChI=1S/C16H14O8/c1-21-13-9(18)5-7-11(14(13)22-2)10-6(15(19)23-3)4-8(17)12(10)24-16(7)20/h5-6,18H,4H2,1-3H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Universidad Aut£noma del Estado de Hidalgo

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi recombinant triosephosphate isomerase after 2 hrs


Bioorg Med Chem Lett 19: 5936-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.055
BindingDB Entry DOI: 10.7270/Q25T3MQF
More data for this
Ligand-Target Pair
Triosephosphate isomerase (TIM)


(Homo sapiens (Human))
BDBM50415050
PNG
(CHEMBL567497)
Show SMILES COC(=O)C1CC(=O)c2oc(=O)c3cc(O)c(OC)c(OC)c3c12
Show InChI InChI=1S/C16H14O8/c1-21-13-9(18)5-7-11(14(13)22-2)10-6(15(19)23-3)4-8(17)12(10)24-16(7)20/h5-6,18H,4H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Universidad Aut£noma del Estado de Hidalgo

Curated by ChEMBL


Assay Description
Inhibition of human recombinant triosephosphate isomerase after 2 hrs


Bioorg Med Chem Lett 19: 5936-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.055
BindingDB Entry DOI: 10.7270/Q25T3MQF
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%