Compile Data Set for Download or QSAR
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Found 32 Enz. Inhib. hit(s) with all data for entry = 50030617
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299217((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  0.0160nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299216((4R,7S,10S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299215((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299209((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  0.470nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299213((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  0.470nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299209((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  0.480nMAssay Description:Displacement of [3H]diprenorphine from rat delta opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299211((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  0.610nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299214((4R,7S,10S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  0.720nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299210((4R,7S,10S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299209((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299217((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]diprenorphine from rat delta opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299209((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to rat delta opioid receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299212((4R,7S,10S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299217((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299211((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]diprenorphine from rat delta opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299215((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299210((4R,7S,10S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299211((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299212((4R,7S,10S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]diprenorphine from rat delta opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299210((4R,7S,10S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]diprenorphine from rat delta opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299212((4R,7S,10S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299213((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]diprenorphine from rat delta opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299216((4R,7S,10S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299216((4R,7S,10S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]diprenorphine from rat delta opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299215((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]diprenorphine from rat delta opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299214((4R,7S,10S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  55nMAssay Description:Displacement of [3H]diprenorphine from rat delta opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299213((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  69nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299214((4R,7S,10S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  145nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299209((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cells assessed as stimulation of [35S]GTPgammaS binding after 1 hr by liquid scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299209((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataEC50:  36nMAssay Description:Agonist activity at rat delta opioid receptor expressed in rat C6 cells assessed as inhibition of forskolin-stimulated cAMP production after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50039029((+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpipe...)
Affinity DataEC50:  166nMAssay Description:Agonist activity at rat delta opioid receptor expressed in rat C6 cells assessed as inhibition of forskolin-stimulated cAMP production after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299209((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 1 hr by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed