Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50030863
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302984(6-(benzo[d][1,3]dioxol-5-yl)-N-(furan-3-ylmethyl)q...)
Affinity DataIC50:  63nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataIC50:  63nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302982(6-(benzo[d][1,3]dioxol-5-yl)-N-(pyridin-3-ylmethyl...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302994(6-(furan-2-yl)-N-(furan-3-ylmethyl)quinazolin-4-am...)
Affinity DataIC50:  111nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302981(6-(benzo[d][1,3]dioxol-5-yl)-N-(3-methylbenzyl)qui...)
Affinity DataIC50:  126nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302983(6-(benzo[d][1,3]dioxol-5-yl)-N-(3-fluorobenzyl)qui...)
Affinity DataIC50:  126nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302990(6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-(thiophe...)
Affinity DataIC50:  141nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302993(CHEMBL566914 | N-(3-fluorobenzyl)-6-(furan-2-yl)qu...)
Affinity DataIC50:  141nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303000(6-(3,5-dimethylisoxazol-4-yl)-N-(thiophen-2-ylmeth...)
Affinity DataIC50:  158nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302998(6-(3,5-dimethylisoxazol-4-yl)-N-(3-fluorobenzyl)qu...)
Affinity DataIC50:  178nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302985(6-(benzo[d][1,3]dioxol-5-yl)-N-((4-methylthiophen-...)
Affinity DataIC50:  178nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302991(6-(furan-2-yl)-N-(3-methylbenzyl)quinazolin-4-amin...)
Affinity DataIC50:  224nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302995(6-(furan-2-yl)-N-(thiophen-2-ylmethyl)quinazolin-4...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302996(6-(3,5-dimethylisoxazol-4-yl)-N-(3-methylbenzyl)qu...)
Affinity DataIC50:  282nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302988(6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-(pyridin...)
Affinity DataIC50:  447nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302999(6-(3,5-dimethylisoxazol-4-yl)-N-((4-methylthiophen...)
Affinity DataIC50:  501nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302989(6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-((4-meth...)
Affinity DataIC50:  501nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302987(6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-(3-methy...)
Affinity DataIC50:  631nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302977(CHEMBL568169 | N-(3-fluorobenzyl)-6-(3-methoxyphen...)
Affinity DataIC50:  708nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302992(6-(furan-2-yl)-N-(pyridin-3-ylmethyl)quinazolin-4-...)
Affinity DataIC50:  794nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302980(6-(3-methoxyphenyl)-N-(thiophen-2-ylmethyl)quinazo...)
Affinity DataIC50:  891nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302997(6-(3,5-dimethylisoxazol-4-yl)-N-(pyridin-3-ylmethy...)
Affinity DataIC50:  891nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302978(CHEMBL582794 | N-(furan-3-ylmethyl)-6-(3-methoxyph...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302979(6-(3-methoxyphenyl)-N-((4-methylthiophen-2-yl)meth...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302975(6-(3-methoxyphenyl)-N-(3-methylbenzyl)quinazolin-4...)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302976(6-(3-methoxyphenyl)-N-(pyridin-3-ylmethyl)quinazol...)
Affinity DataIC50:  3.55E+3nMAssay Description:Inhibition of Clk4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396((1E)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylide...)
Affinity DataKd:  12nMAssay Description:Binding affinity to Dyrk1A assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform gamma-3(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396((1E)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylide...)
Affinity DataKd:  290nMAssay Description:Binding affinity to CSNK1G3 assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform gamma-2(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396((1E)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylide...)
Affinity DataKd:  270nMAssay Description:Binding affinity to CSNK1G2 assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396((1E)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylide...)
Affinity DataKd:  300nMAssay Description:Binding affinity to CSNK1E assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396((1E)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylide...)
Affinity DataKd:  150nMAssay Description:Binding affinity to CSNK1D assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396((1E)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylide...)
Affinity DataKd:  30nMAssay Description:Binding affinity to Clk4 assessed as dissociation constantMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396((1E)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylide...)
Affinity DataKd:  3.00E+3nMAssay Description:Binding affinity to Clk3 assessed as dissociation constantMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396((1E)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylide...)
Affinity DataKd:  95nMAssay Description:Binding affinity to Clk2 assessed as dissociation constantMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396((1E)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylide...)
Affinity DataKd:  19nMAssay Description:Binding affinity to Clk1 assessed as dissociation constantMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataKd:  230nMAssay Description:Binding affinity to EGFR assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataKd:  430nMAssay Description:Binding affinity to Dyrk1B assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataKd:  27nMAssay Description:Binding affinity to Dyrk1A assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataKd:  50nMAssay Description:Binding affinity to Clk4 assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataKd:  470nMAssay Description:Binding affinity to Clk3 assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataKd:  680nMAssay Description:Binding affinity to Clk2 assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50302986(6-(benzo[d][1,3]dioxol-5-yl)-N-(thiophen-2-ylmethy...)
Affinity DataKd:  37nMAssay Description:Binding affinity to Clk1 assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396((1E)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylide...)
Affinity DataKd:  290nMAssay Description:Binding affinity to Ysk4 assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396((1E)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylide...)
Affinity DataKd:  130nMAssay Description:Binding affinity to Dyrk1B assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396((1E)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylide...)
Affinity DataKd:  130nMAssay Description:Binding affinity to PIM1 assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM80396((1E)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylide...)
Affinity DataKd:  280nMAssay Description:Binding affinity to PIM3 assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed