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PubMed code 19919895

Compile data set for download or QSAR
Found 54 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304919
PNG
(CHEMBL595268 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES CCCCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C20H32N2O4S/c1-6-7-8-20(4,5)19(23)21-17-13-15(2)16(3)18(14-17)27(24,25)22-9-11-26-12-10-22/h13-14H,6-12H2,1-5H3,(H,21,23)
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1.10n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304926
PNG
(CHEMBL602105 | N-(3,4-dimethyl-5-(piperidin-1-ylsu...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCCCC1
Show InChI InChI=1S/C19H30N2O3S/c1-6-19(4,5)18(22)20-16-12-14(2)15(3)17(13-16)25(23,24)21-10-8-7-9-11-21/h12-13H,6-11H2,1-5H3,(H,20,22)
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2.70n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304916
PNG
(CHEMBL593625 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES Cc1cc(NC(=O)C(C)(C(F)(F)F)C(F)(F)F)cc(c1C)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C17H20F6N2O4S/c1-10-8-12(24-14(26)15(3,16(18,19)20)17(21,22)23)9-13(11(10)2)30(27,28)25-4-6-29-7-5-25/h8-9H,4-7H2,1-3H3,(H,24,26)
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6.60n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304925
PNG
(CHEMBL602128 | N-(3,4-dimethyl-5-(thiazolidin-3-yl...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCSC1
Show InChI InChI=1S/C17H26N2O3S2/c1-6-17(4,5)16(20)18-14-9-12(2)13(3)15(10-14)24(21,22)19-7-8-23-11-19/h9-10H,6-8,11H2,1-5H3,(H,18,20)
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6.90n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304935
PNG
(CHEMBL605199 | N-[3-(1,1-Dioxo-1lambda*6*-thiomorp...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCS(=O)(=O)CC1
Show InChI InChI=1S/C18H28N2O5S2/c1-6-18(4,5)17(21)19-15-11-13(2)14(3)16(12-15)27(24,25)20-7-9-26(22,23)10-8-20/h11-12H,6-10H2,1-5H3,(H,19,21)
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8.40n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304924
PNG
(CHEMBL602591 | N-(3-(azepan-1-ylsulfonyl)-4,5-dime...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCCCCC1
Show InChI InChI=1S/C20H32N2O3S/c1-6-20(4,5)19(23)21-17-13-15(2)16(3)18(14-17)26(24,25)22-11-9-7-8-10-12-22/h13-14H,6-12H2,1-5H3,(H,21,23)
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9n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304918
PNG
(CHEMBL595035 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES CCCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C19H30N2O4S/c1-6-7-19(4,5)18(22)20-16-12-14(2)15(3)17(13-16)26(23,24)21-8-10-25-11-9-21/h12-13H,6-11H2,1-5H3,(H,20,22)
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9.70n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304920
PNG
(2,2-dimethyl-N-(7-(morpholinosulfonyl)-2,3-dihydro...)
Show SMILES CCC(C)(C)C(=O)Nc1cc2CCCc2c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C19H28N2O4S/c1-4-19(2,3)18(22)20-15-12-14-6-5-7-16(14)17(13-15)26(23,24)21-8-10-25-11-9-21/h12-13H,4-11H2,1-3H3,(H,20,22)
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12n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304921
PNG
(2,2-dimethyl-N-(4-(morpholinosulfonyl)-5,6,7,8-tet...)
Show SMILES CCC(C)(C)C(=O)Nc1cc2CCCCc2c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C20H30N2O4S/c1-4-20(2,3)19(23)21-16-13-15-7-5-6-8-17(15)18(14-16)27(24,25)22-9-11-26-12-10-22/h13-14H,4-12H2,1-3H3,(H,21,23)
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14n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304914
PNG
(CHEMBL593166 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES Cc1cc(NC(=O)C2C(C)(C)C2(C)C)cc(c1C)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C20H30N2O4S/c1-13-11-15(21-18(23)17-19(3,4)20(17,5)6)12-16(14(13)2)27(24,25)22-7-9-26-10-8-22/h11-12,17H,7-10H2,1-6H3,(H,21,23)
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16n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304917
PNG
(CHEMBL596401 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C18H28N2O4S/c1-6-18(4,5)17(21)19-15-11-13(2)14(3)16(12-15)25(22,23)20-7-9-24-10-8-20/h11-12H,6-10H2,1-5H3,(H,19,21)
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17n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50277339
PNG
(2,2,3,3-tetramethyl-N-(4-methyl-3-(morpholinosulfo...)
Show SMILES Cc1ccc(NC(=O)C2C(C)(C)C2(C)C)cc1S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C19H28N2O4S/c1-13-6-7-14(20-17(22)16-18(2,3)19(16,4)5)12-15(13)26(23,24)21-8-10-25-11-9-21/h6-7,12,16H,8-11H2,1-5H3,(H,20,22)
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23n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304915
PNG
(CHEMBL594553 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES Cc1cc(NC(=O)C(C)(C)C)cc(c1C)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C17H26N2O4S/c1-12-10-14(18-16(20)17(3,4)5)11-15(13(12)2)24(21,22)19-6-8-23-9-7-19/h10-11H,6-9H2,1-5H3,(H,18,20)
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40n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304934
PNG
((R)-N-(3-(2-(hydroxymethyl)pyrrolidin-1-ylsulfonyl...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCC[C@@H]1CO
Show InChI InChI=1S/C19H30N2O4S/c1-6-19(4,5)18(23)20-15-10-13(2)14(3)17(11-15)26(24,25)21-9-7-8-16(21)12-22/h10-11,16,22H,6-9,12H2,1-5H3,(H,20,23)/t16-/m1/s1
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43n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304923
PNG
(CHEMBL571323 | N-(3-(N-(cyclopropylmethyl)sulfamoy...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)NCC1CC1
Show InChI InChI=1S/C18H28N2O3S/c1-6-18(4,5)17(21)20-15-9-12(2)13(3)16(10-15)24(22,23)19-11-14-7-8-14/h9-10,14,19H,6-8,11H2,1-5H3,(H,20,21)
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66n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304933
PNG
((S)-N-(3-(3-hydroxypyrrolidin-1-ylsulfonyl)-4,5-di...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CC[C@H](O)C1
Show InChI InChI=1S/C18H28N2O4S/c1-6-18(4,5)17(22)19-14-9-12(2)13(3)16(10-14)25(23,24)20-8-7-15(21)11-20/h9-10,15,21H,6-8,11H2,1-5H3,(H,19,22)/t15-/m0/s1
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90n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304922
PNG
(CHEMBL592264 | N-(3-(N-cyclopentylsulfamoyl)-4,5-d...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)NC1CCCC1
Show InChI InChI=1S/C19H30N2O3S/c1-6-19(4,5)18(22)20-16-11-13(2)14(3)17(12-16)25(23,24)21-15-9-7-8-10-15/h11-12,15,21H,6-10H2,1-5H3,(H,20,22)
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94n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304929
PNG
(CHEMBL611937 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES COCCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C19H30N2O5S/c1-14-12-16(20-18(22)19(3,4)6-9-25-5)13-17(15(14)2)27(23,24)21-7-10-26-11-8-21/h12-13H,6-11H2,1-5H3,(H,20,22)
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110n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304927
PNG
(CHEMBL593167 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES Cc1cc(NC(=O)C(C)(C)c2ccccc2)cc(c1C)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C22H28N2O4S/c1-16-14-19(23-21(25)22(3,4)18-8-6-5-7-9-18)15-20(17(16)2)29(26,27)24-10-12-28-13-11-24/h5-9,14-15H,10-13H2,1-4H3,(H,23,25)
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120n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50304919
PNG
(CHEMBL595268 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES CCCCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C20H32N2O4S/c1-6-7-8-20(4,5)19(23)21-17-13-15(2)16(3)18(14-17)27(24,25)22-9-11-26-12-10-22/h13-14H,6-12H2,1-5H3,(H,21,23)
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140n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304930
PNG
(2,2-dimethyl-N-(4-methyl-3-(morpholinosulfonyl)phe...)
Show SMILES CCC(C)(C)C(=O)Nc1ccc(C)c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C17H26N2O4S/c1-5-17(3,4)16(20)18-14-7-6-13(2)15(12-14)24(21,22)19-8-10-23-11-9-19/h6-7,12H,5,8-11H2,1-4H3,(H,18,20)
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290n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304932
PNG
(2,2-dimethyl-N-(2,3,4-trimethyl-5-(morpholinosulfo...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(c(C)c(C)c1C)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C19H30N2O4S/c1-7-19(5,6)18(22)20-16-12-17(15(4)13(2)14(16)3)26(23,24)21-8-10-25-11-9-21/h12H,7-11H2,1-6H3,(H,20,22)
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410n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50304926
PNG
(CHEMBL602105 | N-(3,4-dimethyl-5-(piperidin-1-ylsu...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCCCC1
Show InChI InChI=1S/C19H30N2O3S/c1-6-19(4,5)18(22)20-16-12-14(2)15(3)17(13-16)25(23,24)21-10-8-7-9-11-21/h12-13H,6-11H2,1-5H3,(H,20,22)
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650n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304931
PNG
(CHEMBL591093 | N-(2,4-dimethyl-5-(morpholinosulfon...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(c(C)cc1C)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C18H28N2O4S/c1-6-18(4,5)17(21)19-15-12-16(14(3)11-13(15)2)25(22,23)20-7-9-24-10-8-20/h11-12H,6-10H2,1-5H3,(H,19,21)
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760n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50304916
PNG
(CHEMBL593625 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES Cc1cc(NC(=O)C(C)(C(F)(F)F)C(F)(F)F)cc(c1C)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C17H20F6N2O4S/c1-10-8-12(24-14(26)15(3,16(18,19)20)17(21,22)23)9-13(11(10)2)30(27,28)25-4-6-29-7-5-25/h8-9H,4-7H2,1-3H3,(H,24,26)
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780n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50304918
PNG
(CHEMBL595035 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES CCCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C19H30N2O4S/c1-6-7-19(4,5)18(22)20-16-12-14(2)15(3)17(13-16)26(23,24)21-8-10-25-11-9-21/h12-13H,6-11H2,1-5H3,(H,20,22)
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830n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50304914
PNG
(CHEMBL593166 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES Cc1cc(NC(=O)C2C(C)(C)C2(C)C)cc(c1C)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C20H30N2O4S/c1-13-11-15(21-18(23)17-19(3,4)20(17,5)6)12-16(14(13)2)27(24,25)22-7-9-26-10-8-22/h11-12,17H,7-10H2,1-6H3,(H,21,23)
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1.10E+3n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50304921
PNG
(2,2-dimethyl-N-(4-(morpholinosulfonyl)-5,6,7,8-tet...)
Show SMILES CCC(C)(C)C(=O)Nc1cc2CCCCc2c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C20H30N2O4S/c1-4-20(2,3)19(23)21-16-13-15-7-5-6-8-17(15)18(14-16)27(24,25)22-9-11-26-12-10-22/h13-14H,4-12H2,1-3H3,(H,21,23)
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1.40E+3n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50304920
PNG
(2,2-dimethyl-N-(7-(morpholinosulfonyl)-2,3-dihydro...)
Show SMILES CCC(C)(C)C(=O)Nc1cc2CCCc2c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C19H28N2O4S/c1-4-19(2,3)18(22)20-15-12-14-6-5-7-16(14)17(13-15)26(23,24)21-8-10-25-11-9-21/h12-13H,4-11H2,1-3H3,(H,20,22)
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1.70E+3n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50304924
PNG
(CHEMBL602591 | N-(3-(azepan-1-ylsulfonyl)-4,5-dime...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCCCCC1
Show InChI InChI=1S/C20H32N2O3S/c1-6-20(4,5)19(23)21-17-13-15(2)16(3)18(14-17)26(24,25)22-11-9-7-8-10-12-22/h13-14H,6-12H2,1-5H3,(H,21,23)
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1.80E+3n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50304928
PNG
(CHEMBL593622 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES Cc1cc(NC(=O)C(C)(C)O)cc(c1C)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C16H24N2O5S/c1-11-9-13(17-15(19)16(3,4)20)10-14(12(11)2)24(21,22)18-5-7-23-8-6-18/h9-10,20H,5-8H2,1-4H3,(H,17,19)
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2.08E+3n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50304925
PNG
(CHEMBL602128 | N-(3,4-dimethyl-5-(thiazolidin-3-yl...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCSC1
Show InChI InChI=1S/C17H26N2O3S2/c1-6-17(4,5)16(20)18-14-9-12(2)13(3)15(10-14)24(21,22)19-7-8-23-11-19/h9-10H,6-8,11H2,1-5H3,(H,18,20)
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2.10E+3n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50304917
PNG
(CHEMBL596401 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C18H28N2O4S/c1-6-18(4,5)17(21)19-15-11-13(2)14(3)16(12-15)25(22,23)20-7-9-24-10-8-20/h11-12H,6-10H2,1-5H3,(H,19,21)
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2.50E+3n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50304915
PNG
(CHEMBL594553 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES Cc1cc(NC(=O)C(C)(C)C)cc(c1C)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C17H26N2O4S/c1-12-10-14(18-16(20)17(3,4)5)11-15(13(12)2)24(21,22)19-6-8-23-9-7-19/h10-11H,6-9H2,1-5H3,(H,18,20)
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3.10E+3n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50277339
PNG
(2,2,3,3-tetramethyl-N-(4-methyl-3-(morpholinosulfo...)
Show SMILES Cc1ccc(NC(=O)C2C(C)(C)C2(C)C)cc1S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C19H28N2O4S/c1-13-6-7-14(20-17(22)16-18(2,3)19(16,4)5)12-15(13)26(23,24)21-8-10-25-11-9-21/h6-7,12,16H,8-11H2,1-5H3,(H,20,22)
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3.40E+3n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50304922
PNG
(CHEMBL592264 | N-(3-(N-cyclopentylsulfamoyl)-4,5-d...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)NC1CCCC1
Show InChI InChI=1S/C19H30N2O3S/c1-6-19(4,5)18(22)20-16-11-13(2)14(3)17(12-16)25(23,24)21-15-9-7-8-10-15/h11-12,15,21H,6-10H2,1-5H3,(H,20,22)
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3.40E+3n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50304923
PNG
(CHEMBL571323 | N-(3-(N-(cyclopropylmethyl)sulfamoy...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)NCC1CC1
Show InChI InChI=1S/C18H28N2O3S/c1-6-18(4,5)17(21)20-15-9-12(2)13(3)16(10-15)24(22,23)19-11-14-7-8-14/h9-10,14,19H,6-8,11H2,1-5H3,(H,20,21)
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3.80E+3n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50304921
PNG
(2,2-dimethyl-N-(4-(morpholinosulfonyl)-5,6,7,8-tet...)
Show SMILES CCC(C)(C)C(=O)Nc1cc2CCCCc2c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C20H30N2O4S/c1-4-20(2,3)19(23)21-16-13-15-7-5-6-8-17(15)18(14-16)27(24,25)22-9-11-26-12-10-22/h13-14H,4-12H2,1-3H3,(H,21,23)
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n/an/an/an/a 1.40E+3n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50304925
PNG
(CHEMBL602128 | N-(3,4-dimethyl-5-(thiazolidin-3-yl...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCSC1
Show InChI InChI=1S/C17H26N2O3S2/c1-6-17(4,5)16(20)18-14-9-12(2)13(3)15(10-14)24(21,22)19-7-8-23-11-19/h9-10H,6-8,11H2,1-5H3,(H,18,20)
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n/an/an/an/a 12n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50304920
PNG
(2,2-dimethyl-N-(7-(morpholinosulfonyl)-2,3-dihydro...)
Show SMILES CCC(C)(C)C(=O)Nc1cc2CCCc2c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C19H28N2O4S/c1-4-19(2,3)18(22)20-15-12-14-6-5-7-16(14)17(13-15)26(23,24)21-8-10-25-11-9-21/h12-13H,4-11H2,1-3H3,(H,20,22)
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n/an/an/an/a 1.70E+3n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50304917
PNG
(CHEMBL596401 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C18H28N2O4S/c1-6-18(4,5)17(21)19-15-11-13(2)14(3)16(12-15)25(22,23)20-7-9-24-10-8-20/h11-12H,6-10H2,1-5H3,(H,19,21)
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n/an/an/an/a 38n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50304926
PNG
(CHEMBL602105 | N-(3,4-dimethyl-5-(piperidin-1-ylsu...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCCCC1
Show InChI InChI=1S/C19H30N2O3S/c1-6-19(4,5)18(22)20-16-12-14(2)15(3)17(13-16)25(23,24)21-10-8-7-9-11-21/h12-13H,6-11H2,1-5H3,(H,20,22)
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n/an/an/an/a 13n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50304919
PNG
(CHEMBL595268 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES CCCCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C20H32N2O4S/c1-6-7-8-20(4,5)19(23)21-17-13-15(2)16(3)18(14-17)27(24,25)22-9-11-26-12-10-22/h13-14H,6-12H2,1-5H3,(H,21,23)
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n/an/an/an/a 82n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50304915
PNG
(CHEMBL594553 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES Cc1cc(NC(=O)C(C)(C)C)cc(c1C)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C17H26N2O4S/c1-12-10-14(18-16(20)17(3,4)5)11-15(13(12)2)24(21,22)19-6-8-23-9-7-19/h10-11H,6-9H2,1-5H3,(H,18,20)
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n/an/an/an/a 90n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50304916
PNG
(CHEMBL593625 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES Cc1cc(NC(=O)C(C)(C(F)(F)F)C(F)(F)F)cc(c1C)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C17H20F6N2O4S/c1-10-8-12(24-14(26)15(3,16(18,19)20)17(21,22)23)9-13(11(10)2)30(27,28)25-4-6-29-7-5-25/h8-9H,4-7H2,1-3H3,(H,24,26)
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n/an/an/an/a 11n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50304934
PNG
((R)-N-(3-(2-(hydroxymethyl)pyrrolidin-1-ylsulfonyl...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCC[C@@H]1CO
Show InChI InChI=1S/C19H30N2O4S/c1-6-19(4,5)18(23)20-15-10-13(2)14(3)17(11-15)26(24,25)21-9-7-8-16(21)12-22/h10-11,16,22H,6-9,12H2,1-5H3,(H,20,23)/t16-/m1/s1
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n/an/an/an/a 98n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50304924
PNG
(CHEMBL602591 | N-(3-(azepan-1-ylsulfonyl)-4,5-dime...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCCCCC1
Show InChI InChI=1S/C20H32N2O3S/c1-6-20(4,5)19(23)21-17-13-15(2)16(3)18(14-17)26(24,25)22-11-9-7-8-10-12-22/h13-14H,6-12H2,1-5H3,(H,21,23)
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n/an/an/an/a 22n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50304933
PNG
((S)-N-(3-(3-hydroxypyrrolidin-1-ylsulfonyl)-4,5-di...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CC[C@H](O)C1
Show InChI InChI=1S/C18H28N2O4S/c1-6-18(4,5)17(22)19-14-9-12(2)13(3)16(10-14)25(23,24)20-8-7-15(21)11-20/h9-10,15,21H,6-8,11H2,1-5H3,(H,19,22)/t15-/m0/s1
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n/an/an/an/a 73n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50304914
PNG
(CHEMBL593166 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES Cc1cc(NC(=O)C2C(C)(C)C2(C)C)cc(c1C)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C20H30N2O4S/c1-13-11-15(21-18(23)17-19(3,4)20(17,5)6)12-16(14(13)2)27(24,25)22-7-9-26-10-8-22/h11-12,17H,7-10H2,1-6H3,(H,21,23)
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n/an/an/an/a 66n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50304918
PNG
(CHEMBL595035 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES CCCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C19H30N2O4S/c1-6-7-19(4,5)18(22)20-16-12-14(2)15(3)17(13-16)26(23,24)21-8-10-25-11-9-21/h12-13H,6-11H2,1-5H3,(H,20,22)
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n/an/an/an/a 21n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50304923
PNG
(CHEMBL571323 | N-(3-(N-(cyclopropylmethyl)sulfamoy...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)NCC1CC1
Show InChI InChI=1S/C18H28N2O3S/c1-6-18(4,5)17(21)20-15-9-12(2)13(3)16(10-15)24(22,23)19-11-14-7-8-14/h9-10,14,19H,6-8,11H2,1-5H3,(H,20,21)
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n/an/an/an/a 135n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50277339
PNG
(2,2,3,3-tetramethyl-N-(4-methyl-3-(morpholinosulfo...)
Show SMILES Cc1ccc(NC(=O)C2C(C)(C)C2(C)C)cc1S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C19H28N2O4S/c1-13-6-7-14(20-17(22)16-18(2,3)19(16,4)5)12-15(13)26(23,24)21-8-10-25-11-9-21/h6-7,12,16H,8-11H2,1-5H3,(H,20,22)
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n/an/an/an/a 11n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50304935
PNG
(CHEMBL605199 | N-[3-(1,1-Dioxo-1lambda*6*-thiomorp...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCS(=O)(=O)CC1
Show InChI InChI=1S/C18H28N2O5S2/c1-6-18(4,5)17(21)19-15-11-13(2)14(3)16(12-15)27(24,25)20-7-9-26(22,23)10-8-20/h11-12H,6-10H2,1-5H3,(H,19,21)
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n/an/an/an/a 20n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2 (CB2)


(Rattus norvegicus (Rat))
BDBM50304922
PNG
(CHEMBL592264 | N-(3-(N-cyclopentylsulfamoyl)-4,5-d...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)NC1CCCC1
Show InChI InChI=1S/C19H30N2O3S/c1-6-19(4,5)18(22)20-16-11-13(2)14(3)17(12-16)25(23,24)21-15-9-7-8-10-15/h11-12,15,21H,6-10H2,1-5H3,(H,20,22)
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n/an/an/an/a 98n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at rat brain CB2 receptor by GTPgammaS binding assay


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%