Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50010952![]() (2-(6-Hydroxy-1-pyridin-3-yl-hexyl)-3,5,6-trimethyl...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.00000100 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50406422![]() (CHEMBL2115381) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Reduction of lipid peroxide formed in rat brain homogenates. | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010968![]() (3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyc...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50010960![]() ((E)-7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | 7-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50010949![]() (8-Pyridin-3-yl-8-(2,4,5-trimethyl-3,6-dioxo-cycloh...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50006803![]() (2,3,5-Trimethyl-6-pyridin-3-ylmethyl-[1,4]benzoqui...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50010970![]() (7-Pyridin-3-yl-7-(2,4,5-trimethyl-3,6-dioxo-cycloh...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010958![]() (2,3,5-Trimethyl-6-(1-pyridin-3-yl-heptyl)-[1,4]ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010961![]() (2-Methyl-3-pyridin-3-ylmethyl-[1,4]naphthoquinone ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010945![]() (Acetic acid 6-pyridin-3-yl-6-(2,4,5-trimethyl-3,6-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50010947![]() (6-Pyridin-3-yl-6-(2,4,5-trimethyl-3,6-dioxo-cycloh...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50006811![]() (2-(12-Hydroxy-5,10-dodecadiynyl)-3,5,6-trimethyl-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | Purchase CHEBI CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010952![]() (2-(6-Hydroxy-1-pyridin-3-yl-hexyl)-3,5,6-trimethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010944![]() (2-(5-Hydroxy-1-pyridin-3-yl-pentyl)-3,5,6-trimethy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Reduction of lipid peroxide formed in rat brain homogenates. | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50010966![]() (7-Pyridin-3-yl-7-(2,4,5-trimethyl-3,6-dioxo-cycloh...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010951![]() (Acetic acid 5-pyridin-3-yl-5-(2,4,5-trimethyl-3,6-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50006803![]() (2,3,5-Trimethyl-6-pyridin-3-ylmethyl-[1,4]benzoqui...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50010961![]() (2-Methyl-3-pyridin-3-ylmethyl-[1,4]naphthoquinone ...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50010950![]() (3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyc...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50010957![]() (2-Methyl-3-{2-[pyridin-3-yl-(2,4,5-trimethyl-3,6-d...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010958![]() (2,3,5-Trimethyl-6-(1-pyridin-3-yl-heptyl)-[1,4]ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Reduction of lipid peroxide formed in rat brain homogenates. | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010946![]() (2,3,5-Trimethyl-6-(1-pyridin-3-yl-hept-1-enyl)-[1,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Reduction of lipid peroxide formed in rat brain homogenates. | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010953![]() (2,3,5-Trimethyl-6-(1-pyridin-3-yl-propyl)-[1,4]ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Reduction of lipid peroxide formed in rat brain homogenates. | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50006803![]() (2,3,5-Trimethyl-6-pyridin-3-ylmethyl-[1,4]benzoqui...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Reduction of lipid peroxide formed in rat brain homogenates. | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50010954![]() (2,3,5-Trimethyl-6-(1-pyridin-3-yl-ethyl)-[1,4]benz...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010954![]() (2,3,5-Trimethyl-6-(1-pyridin-3-yl-ethyl)-[1,4]benz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Reduction of lipid peroxide formed in rat brain homogenates. | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010951![]() (Acetic acid 5-pyridin-3-yl-5-(2,4,5-trimethyl-3,6-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Reduction of lipid peroxide formed in rat brain homogenates. | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010952![]() (2-(6-Hydroxy-1-pyridin-3-yl-hexyl)-3,5,6-trimethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Reduction of lipid peroxide formed in rat brain homogenates. | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50010953![]() (2,3,5-Trimethyl-6-(1-pyridin-3-yl-propyl)-[1,4]ben...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010956![]() (2,3,5-Trimethyl-6-(1-pyridin-3-yl-pentyl)-[1,4]ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010953![]() (2,3,5-Trimethyl-6-(1-pyridin-3-yl-propyl)-[1,4]ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Reduction of lipid peroxide formed in rat brain homogenates. | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010956![]() (2,3,5-Trimethyl-6-(1-pyridin-3-yl-pentyl)-[1,4]ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010946![]() (2,3,5-Trimethyl-6-(1-pyridin-3-yl-hept-1-enyl)-[1,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010948![]() (2,3,5-Trimethyl-6-(phenyl-pyridin-3-yl-methyl)-[1,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Reduction of lipid peroxide formed in rat brain homogenates. | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010945![]() (Acetic acid 6-pyridin-3-yl-6-(2,4,5-trimethyl-3,6-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 870 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010944![]() (2-(5-Hydroxy-1-pyridin-3-yl-pentyl)-3,5,6-trimethy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Reduction of lipid peroxide formed in rat brain homogenates. | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50010945![]() (Acetic acid 6-pyridin-3-yl-6-(2,4,5-trimethyl-3,6-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50010959![]() (3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyc...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010949![]() (8-Pyridin-3-yl-8-(2,4,5-trimethyl-3,6-dioxo-cycloh...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Reduction of lipid peroxide formed in rat brain homogenates. | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50010944![]() (2-(5-Hydroxy-1-pyridin-3-yl-pentyl)-3,5,6-trimethy...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50010951![]() (Acetic acid 5-pyridin-3-yl-5-(2,4,5-trimethyl-3,6-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human)) | BDBM50010958![]() (2,3,5-Trimethyl-6-(1-pyridin-3-yl-heptyl)-[1,4]ben...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla... | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010959![]() (3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyc...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010964![]() (2,3-Dimethoxy-5-methyl-6-pyridin-3-ylmethyl-[1,4]b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010949![]() (8-Pyridin-3-yl-8-(2,4,5-trimethyl-3,6-dioxo-cycloh...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010966![]() (7-Pyridin-3-yl-7-(2,4,5-trimethyl-3,6-dioxo-cycloh...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010965![]() (3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyc...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010950![]() (3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyc...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010970![]() (7-Pyridin-3-yl-7-(2,4,5-trimethyl-3,6-dioxo-cycloh...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010954![]() (2,3,5-Trimethyl-6-(1-pyridin-3-yl-ethyl)-[1,4]benz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description Reduction of lipid peroxide formed in rat brain homogenates. | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010947![]() (6-Pyridin-3-yl-6-(2,4,5-trimethyl-3,6-dioxo-cycloh...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010967![]() (3-{3-[Pyridin-3-yl-(2,4,5-trimethyl-3,6-dioxo-cycl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010957![]() (2-Methyl-3-{2-[pyridin-3-yl-(2,4,5-trimethyl-3,6-d...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50010969![]() (3-{3-[Pyridin-3-yl-(2,4,5-trimethyl-3,6-dioxo-cycl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd Curated by ChEMBL | Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells | J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9 | |||||||||||
More data for this Ligand-Target Pair |