Compile Data Set for Download or QSAR
maximum 50k data
Found 70 Enz. Inhib. hit(s) with all data for entry = 50031033
LigandPNGBDBM50305663((3-(1-(1-benzylpiperidin-4-yl)-4-morpholino-1H-pyr...)
Affinity DataIC50:  25nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305645((3-(4-morpholino-7-(piperidin-4-yl)-7H-pyrrolo[2,3...)
Affinity DataIC50:  26nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM35600(pyrazolo pyrimidine, 5e)
Affinity DataIC50:  32nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM35596(pyrazolo pyrimidine, 5a)
Affinity DataIC50:  36nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305306((3-(9-(1-benzylpiperidin-4-yl)-6-morpholino-9H-pur...)
Affinity DataIC50:  45nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305307((3-(6-morpholino-9-(piperidin-4-yl)-9H-purin-2-yl)...)
Affinity DataIC50:  58nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305300(3-(6-morpholino-9-(piperidin-4-yl)-9H-purin-2-yl)p...)
Affinity DataIC50:  65nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305301(3-(9-(1-benzylpiperidin-4-yl)-6-morpholino-9H-puri...)
Affinity DataIC50:  80nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM35600(pyrazolo pyrimidine, 5e)
Affinity DataIC50:  83nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305663((3-(1-(1-benzylpiperidin-4-yl)-4-morpholino-1H-pyr...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305300(3-(6-morpholino-9-(piperidin-4-yl)-9H-purin-2-yl)p...)
Affinity DataIC50:  131nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305301(3-(9-(1-benzylpiperidin-4-yl)-6-morpholino-9H-puri...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305650(4-(2-(1H-indol-6-yl)-9H-purin-6-yl)morpholine | CH...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305662(3-(9-((1-benzylpiperidin-4-yl)methyl)-6-morpholino...)
Affinity DataIC50:  199nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM35596(pyrazolo pyrimidine, 5a)
Affinity DataIC50:  215nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305299(3-(6-morpholino-9H-purin-2-yl)phenol | CHEMBL59351...)
Affinity DataIC50:  232nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305661((3-(9-((1-benzylpiperidin-4-yl)methyl)-6-morpholin...)
Affinity DataIC50:  248nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305645((3-(4-morpholino-7-(piperidin-4-yl)-7H-pyrrolo[2,3...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305646(4-(6-morpholino-9H-purin-2-yl)phenol | CHEMBL59226...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305645((3-(4-morpholino-7-(piperidin-4-yl)-7H-pyrrolo[2,3...)
Affinity DataIC50:  510nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305662(3-(9-((1-benzylpiperidin-4-yl)methyl)-6-morpholino...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305660(4-(2-(thiophen-2-yl)-9H-purin-6-yl)morpholine | CH...)
Affinity DataIC50:  640nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305659(2-(6-morpholino-9H-purin-2-yl)phenol | CHEMBL58540...)
Affinity DataIC50:  667nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305307((3-(6-morpholino-9-(piperidin-4-yl)-9H-purin-2-yl)...)
Affinity DataIC50:  683nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305306((3-(9-(1-benzylpiperidin-4-yl)-6-morpholino-9H-pur...)
Affinity DataIC50:  691nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305300(3-(6-morpholino-9-(piperidin-4-yl)-9H-purin-2-yl)p...)
Affinity DataIC50:  870nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305663((3-(1-(1-benzylpiperidin-4-yl)-4-morpholino-1H-pyr...)
Affinity DataIC50:  975nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM35596(pyrazolo pyrimidine, 5a)
Affinity DataIC50:  993nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305306((3-(9-(1-benzylpiperidin-4-yl)-6-morpholino-9H-pur...)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305652(4-(2-(benzo[d][1,3]dioxol-5-yl)-9H-purin-6-yl)morp...)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305661((3-(9-((1-benzylpiperidin-4-yl)methyl)-6-morpholin...)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305649(4-(2-(4-(methylsulfonyl)phenyl)-9H-purin-6-yl)morp...)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305650(4-(2-(1H-indol-6-yl)-9H-purin-6-yl)morpholine | CH...)
Affinity DataIC50:  2.33E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305299(3-(6-morpholino-9H-purin-2-yl)phenol | CHEMBL59351...)
Affinity DataIC50:  2.34E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM35600(pyrazolo pyrimidine, 5e)
Affinity DataIC50:  2.37E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305662(3-(9-((1-benzylpiperidin-4-yl)methyl)-6-morpholino...)
Affinity DataIC50:  2.38E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305653(4-(2-(thiophen-3-yl)-9H-purin-6-yl)morpholine | CH...)
Affinity DataIC50:  2.38E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305299(3-(6-morpholino-9H-purin-2-yl)phenol | CHEMBL59351...)
Affinity DataIC50:  2.38E+3nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305659(2-(6-morpholino-9H-purin-2-yl)phenol | CHEMBL58540...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305646(4-(6-morpholino-9H-purin-2-yl)phenol | CHEMBL59226...)
Affinity DataIC50:  2.54E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305660(4-(2-(thiophen-2-yl)-9H-purin-6-yl)morpholine | CH...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305647((4-(6-morpholino-9H-purin-2-yl)phenyl)methanol | C...)
Affinity DataIC50:  2.89E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305656(3-(6-morpholino-9H-purin-2-yl)benzonitrile | CHEMB...)
Affinity DataIC50:  2.92E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305651(4-(2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-9H-puri...)
Affinity DataIC50:  3.48E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305655(3-(6-(piperidin-1-yl)-9H-purin-2-yl)phenol | CHEMB...)
Affinity DataIC50:  3.77E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305654(4-(2-(furan-3-yl)-9H-purin-6-yl)morpholine | CHEMB...)
Affinity DataIC50:  3.79E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305653(4-(2-(thiophen-3-yl)-9H-purin-6-yl)morpholine | CH...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305657(4-(2-(3-(methylsulfonyl)phenyl)-9H-purin-6-yl)morp...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305658(CHEMBL589864 | N-(3-(6-morpholino-9H-purin-2-yl)ph...)
Affinity DataIC50:  4.38E+3nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305647((4-(6-morpholino-9H-purin-2-yl)phenyl)methanol | C...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 70 total ) | Next | Last >>
Jump to: