Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50031034
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305679((R)-methyl 2-(5-(4-(aminomethyl)phenyl)-2-methylfu...)
Affinity DataIC50:  25nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305675((R)-3-(1H-benzo[d]imidazol-2-yl)-2-(5-(4-methoxyph...)
Affinity DataIC50:  130nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305678((R)-methyl 3-(1H-benzo[d]imidazol-2-yl)-2-(5-(4-cy...)
Affinity DataIC50:  180nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305680((R)-methyl 3-(1H-benzo[d]imidazol-2-yl)-2-(1-methy...)
Affinity DataIC50:  260nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305677((R)-methyl 3-(1H-benzo[d]imidazol-2-yl)-2-(2-methy...)
Affinity DataIC50:  320nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305673((R)-2-(benzo[b]thiophene-2-carboxamido)-3-(1H-benz...)
Affinity DataIC50:  830nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305681((R)-2-(5-(4-methoxyphenyl)-2-methylfuran-3-carboxa...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305682((2R)-2-[(2-methyl-5-phenyl-pyrazol-3-yl)carbonylam...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305671((R)-2-(3-(1H-indol-2-yl)propanamido)-3-(1H-benzo[d...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305674((R)-3-(1H-benzo[d]imidazol-2-yl)-2-(2-methylfuran-...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305672((R)-3-(1H-benzo[d]imidazol-2-yl)-2-(3-phenylpropan...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305664(5-cyano-1H-benzo[d]imidazole-2-carboxylic acid | C...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50009123(5-methyl-1H-indole-2-carboxylic acid | 5-methylind...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305665(5-methyl-1H-benzo[d]imidazole-2-carboxylic acid | ...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305670((R)-3-(1H-benzo[d]imidazol-2-yl)-2-propionamidopro...)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305676((R)-methyl 3-(1H-benzo[d]imidazol-2-yl)-2-(5-(4-me...)
Affinity DataIC50:  9.20E+4nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305669(3-(1H-indol-2-yl)propanoic acid | CHEMBL595027)
Affinity DataIC50:  4.50E+5nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305666(6-methyl-1H-indole-2-carboxylic acid | CHEMBL59600...)
Affinity DataIC50:  6.30E+5nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305668(3-(1H-benzimidazol-2-yl)propanoic acid | 3-(1H-ben...)
Affinity DataIC50:  7.40E+5nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305667(CHEMBL595026 | N-ethyl-5-methyl-1H-benzo[d]imidazo...)
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305679((R)-methyl 2-(5-(4-(aminomethyl)phenyl)-2-methylfu...)
Affinity DataKd:  530nMAssay Description:Binding affinity to 8His-tagged Pin1 (45-163) PPIase domain by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50009123(5-methyl-1H-indole-2-carboxylic acid | 5-methylind...)
Affinity DataKd:  2.00E+5nMAssay Description:Binding affinity to 8His-tagged Pin1 (45-163) PPIase domain by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50305673((R)-2-(benzo[b]thiophene-2-carboxamido)-3-(1H-benz...)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to 8His-tagged Pin1 (45-163) PPIase domain by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair