Compile Data Set for Download or QSAR
maximum 50k data
Found 60 Enz. Inhib. hit(s) with all data for entry = 50031216
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309123(4-(6-(piperazin-1-yl)-5-(pyrrolidin-1-yl)pyrazin-2...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309122(4-(6-(1,4-diazepan-1-yl)-5-(pyrrolidin-1-yl)pyrazi...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309120((1-(6-(pyridin-4-yl)-3-(pyrrolidin-1-yl)pyrazin-2-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309123(4-(6-(piperazin-1-yl)-5-(pyrrolidin-1-yl)pyrazin-2...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309116(1-(6-(pyridin-4-yl)-3-(pyrrolidin-1-yl)pyrazin-2-y...)
Affinity DataIC50:  39nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309121(CHEMBL602041 | N-methyl-1-(1-(6-(pyridin-4-yl)-3-(...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309117(3-(piperazin-1-yl)-5-(pyridin-4-yl)-2-(pyrrolidin-...)
Affinity DataIC50:  62nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309118(1-(6-(pyridin-4-yl)-3-(pyrrolidin-1-yl)pyrazin-2-y...)
Affinity DataIC50:  62nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309126(2-(4-(6-(pyridin-4-yl)-3-(pyrrolidin-1-yl)pyrazin-...)
Affinity DataIC50:  78nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309124(1-(3-(pyrrolidin-1-yl)-6-(1H-pyrrolo[2,3-b]pyridin...)
Affinity DataIC50:  89nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309120((1-(6-(pyridin-4-yl)-3-(pyrrolidin-1-yl)pyrazin-2-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309121(CHEMBL602041 | N-methyl-1-(1-(6-(pyridin-4-yl)-3-(...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309122(4-(6-(1,4-diazepan-1-yl)-5-(pyrrolidin-1-yl)pyrazi...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309119(CHEMBL591047 | N-methyl-1-(6-(pyridin-4-yl)-3-(pyr...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309118(1-(6-(pyridin-4-yl)-3-(pyrrolidin-1-yl)pyrazin-2-y...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309126(2-(4-(6-(pyridin-4-yl)-3-(pyrrolidin-1-yl)pyrazin-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309125(2-(4-(3-(dimethylamino)-6-(pyridin-4-yl)pyrazin-2-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309124(1-(3-(pyrrolidin-1-yl)-6-(1H-pyrrolo[2,3-b]pyridin...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309116(1-(6-(pyridin-4-yl)-3-(pyrrolidin-1-yl)pyrazin-2-y...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309113(1-methyl-4-(6-(pyridin-4-yl)-3-(pyrrolidin-1-yl)py...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309103(3-(4-methyl-1,4-diazepan-1-yl)-5-(1H-pyrrolo[2,3-b...)
Affinity DataIC50:  530nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309114(1-methyl-4-(3-(piperidin-1-yl)-6-(pyridin-4-yl)pyr...)
Affinity DataIC50:  560nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309117(3-(piperazin-1-yl)-5-(pyridin-4-yl)-2-(pyrrolidin-...)
Affinity DataIC50:  610nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309105(5-(1H-indazol-5-yl)-3-(4-methyl-1,4-diazepan-1-yl)...)
Affinity DataIC50:  950nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309125(2-(4-(3-(dimethylamino)-6-(pyridin-4-yl)pyrazin-2-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309103(3-(4-methyl-1,4-diazepan-1-yl)-5-(1H-pyrrolo[2,3-b...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309108(CHEMBL601834 | N,N-dimethyl-3-(4-methyl-1,4-diazep...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309119(CHEMBL591047 | N-methyl-1-(6-(pyridin-4-yl)-3-(pyr...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309105(5-(1H-indazol-5-yl)-3-(4-methyl-1,4-diazepan-1-yl)...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309107(CHEMBL589578 | N-methyl-3-(4-methyl-1,4-diazepan-1...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309104(5-(1H-indazol-4-yl)-3-(4-methyl-1,4-diazepan-1-yl)...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309097(2-(4-(3-amino-6-(pyridin-4-yl)pyrazin-2-yl)piperaz...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309098(3-(4-methyl-1,4-diazepan-1-yl)-5-(pyridin-4-yl)pyr...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309109(CHEMBL589336 | N,N-diethyl-3-(4-methyl-1,4-diazepa...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309102(3-(4-methyl-1,4-diazepan-1-yl)-5-(1H-pyrazol-3-yl)...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309110(2-(3-(4-methyl-1,4-diazepan-1-yl)-5-(pyridin-4-yl)...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309098(3-(4-methyl-1,4-diazepan-1-yl)-5-(pyridin-4-yl)pyr...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309097(2-(4-(3-amino-6-(pyridin-4-yl)pyrazin-2-yl)piperaz...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309113(1-methyl-4-(6-(pyridin-4-yl)-3-(pyrrolidin-1-yl)py...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309115(4-(3-(4-methyl-1,4-diazepan-1-yl)-5-(pyridin-4-yl)...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309108(CHEMBL601834 | N,N-dimethyl-3-(4-methyl-1,4-diazep...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309109(CHEMBL589336 | N,N-diethyl-3-(4-methyl-1,4-diazepa...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309107(CHEMBL589578 | N-methyl-3-(4-methyl-1,4-diazepan-1...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309104(5-(1H-indazol-4-yl)-3-(4-methyl-1,4-diazepan-1-yl)...)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309106(5-(1H-indazol-6-yl)-3-(4-methyl-1,4-diazepan-1-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309111(CHEMBL590238 | N-(2-methoxyethyl)-3-(4-methyl-1,4-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309106(5-(1H-indazol-6-yl)-3-(4-methyl-1,4-diazepan-1-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309114(1-methyl-4-(3-(piperidin-1-yl)-6-(pyridin-4-yl)pyr...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309101(5-(2-aminopyridin-4-yl)-3-(4-methyl-1,4-diazepan-1...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50309102(3-(4-methyl-1,4-diazepan-1-yl)-5-(1H-pyrazol-3-yl)...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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