Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50031392
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312552(3'-(3-nitrophenyl)epibatidine | CHEMBL1096352)
Affinity DataKi:  0.00800nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312557(3'-(3-Dimethylaminophenyl)epibatidine | CHEMBL1084...)
Affinity DataKi:  0.00900nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312547(3'-(3-Fluorophenyl)epibatidine | CHEMBL1097692)
Affinity DataKi:  0.0120nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312549(3'-(3-Chlorophenyl)epibatidine | CHEMBL1098031)
Affinity DataKi:  0.0130nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312551(3'-(4-Nitrophenyl)epibatidine | CHEMBL1098033)
Affinity DataKi:  0.0150nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312550(3'-(3-Bromophenyl)epibatidine | CHEMBL1098032)
Affinity DataKi:  0.0160nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312546((1R,2R,4S)-2-(6-chloro-5-(4-fluorophenyl)pyridin-3...)
Affinity DataKi:  0.0170nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312554(3'-(3-Aminophenyl)epibatidine | CHEMBL1076992)
Affinity DataKi:  0.0170nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312556((1R,2R,4S)-2-(6-chloro-5-(3-methoxyphenyl)pyridin-...)
Affinity DataKi:  0.0190nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312545((1R,2R,4S)-2-(6-chloro-5-phenylpyridin-3-yl)-7-aza...)
Affinity DataKi:  0.0210nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312555(3'-(4-Methoxylphenyl)epibatidine | CHEMBL1085916)
Affinity DataKi:  0.0220nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50143320((+)-epibatidine | (-)-1-epidatidine | (1S,2S,4R)-2...)
Affinity DataKi:  0.0260nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312553(3'-(4-Aminophenyl)epibatidine | CHEMBL1096353)
Affinity DataKi:  0.0340nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312548(3'-(4-Chlorophenyl)epibatidine | CHEMBL1098030)
Affinity DataKi:  0.0390nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312549(3'-(3-Chlorophenyl)epibatidine | CHEMBL1098031)
Affinity DataKi:  30.5nMAssay Description:Displacement of [3H]iodo-MLA from alpha7 nAChR in rat cerebral cortex after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312550(3'-(3-Bromophenyl)epibatidine | CHEMBL1098032)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]iodo-MLA from alpha7 nAChR in rat cerebral cortex after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312555(3'-(4-Methoxylphenyl)epibatidine | CHEMBL1085916)
Affinity DataKi:  175nMAssay Description:Displacement of [3H]iodo-MLA from alpha7 nAChR in rat cerebral cortex after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312548(3'-(4-Chlorophenyl)epibatidine | CHEMBL1098030)
Affinity DataKi:  209nMAssay Description:Displacement of [3H]iodo-MLA from alpha7 nAChR in rat cerebral cortex after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312552(3'-(3-nitrophenyl)epibatidine | CHEMBL1096352)
Affinity DataKi:  229nMAssay Description:Displacement of [3H]iodo-MLA from alpha7 nAChR in rat cerebral cortex after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312553(3'-(4-Aminophenyl)epibatidine | CHEMBL1096353)
Affinity DataKi:  234nMAssay Description:Displacement of [3H]iodo-MLA from alpha7 nAChR in rat cerebral cortex after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312547(3'-(3-Fluorophenyl)epibatidine | CHEMBL1097692)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]iodo-MLA from alpha7 nAChR in rat cerebral cortex after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312551(3'-(4-Nitrophenyl)epibatidine | CHEMBL1098033)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]iodo-MLA from alpha7 nAChR in rat cerebral cortex after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312554(3'-(3-Aminophenyl)epibatidine | CHEMBL1076992)
Affinity DataKi:  256nMAssay Description:Displacement of [3H]iodo-MLA from alpha7 nAChR in rat cerebral cortex after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312545((1R,2R,4S)-2-(6-chloro-5-phenylpyridin-3-yl)-7-aza...)
Affinity DataKi:  260nMAssay Description:Displacement of [3H]iodo-MLA from alpha7 nAChR in rat cerebral cortex after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312546((1R,2R,4S)-2-(6-chloro-5-(4-fluorophenyl)pyridin-3...)
Affinity DataKi:  309nMAssay Description:Displacement of [3H]iodo-MLA from alpha7 nAChR in rat cerebral cortex after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312556((1R,2R,4S)-2-(6-chloro-5-(3-methoxyphenyl)pyridin-...)
Affinity DataKi:  558nMAssay Description:Displacement of [3H]iodo-MLA from alpha7 nAChR in rat cerebral cortex after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50312557(3'-(3-Dimethylaminophenyl)epibatidine | CHEMBL1084...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]iodo-MLA from alpha7 nAChR in rat cerebral cortex after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed