Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50034616
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)
Affinity DataIC50:  12nMAssay Description:Inhibition of MEK1 in human HT-29 cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)
Affinity DataIC50:  22nMAssay Description:Inhibition of MEK1 in human LOX cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)
Affinity DataIC50:  25nMAssay Description:Inhibition of MEK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)
Affinity DataIC50:  69nMAssay Description:Inhibition of MEK1 in human MIA PaCa-2 cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)
Affinity DataIC50:  82nMAssay Description:Inhibition of MEK1 in human H460 cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed