Compile Data Set for Download or QSAR
maximum 50k data
Found 49 Enz. Inhib. hit(s) with all data for entry = 50031157
TargetTransporter(Rattus norvegicus (rat))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308250((1R,5R,6R)-1-(3,4-dichlorophenyl)-6-(ethoxymethyl)...)
Affinity DataKi:  0.135nMAssay Description:Displacement of [N-methyl-3H]nisoxetine from rat hippocampus NET by filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(MOUSE)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308250((1R,5R,6R)-1-(3,4-dichlorophenyl)-6-(ethoxymethyl)...)
Affinity DataKi:  0.851nMAssay Description:Displacement of [3H]citalopram from mouse cortex SERT by filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308250((1R,5R,6R)-1-(3,4-dichlorophenyl)-6-(ethoxymethyl)...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308250((1R,5R,6R)-1-(3,4-dichlorophenyl)-6-(ethoxymethyl)...)
Affinity DataKi:  1.26E+4nMAssay Description:from Dfrom ifrom sfrom pfrom lfrom afrom cfrom efrom mfrom efrom nfrom tfrom from ofrom ffrom from [from 3from Hfrom ]from dfrom ofrom ffrom efrom tf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308254(CHEMBL610220 | exo-6-(3,4-Dichlorophenyl)-6-{[(2,2...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human CYP2CD6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308248(CHEMBL598215 | exo-6-[(Methyloxy)methyl]-1-(2-naph...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308246(CHEMBL598644 | exo-6-(3,4-Dichlorophenyl)-3-azabic...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human CYP2CD6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308253(CHEMBL610795 | exo-6-{[(Cyclopropylmethyl)oxy]meth...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human CYP2CD6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308245(CHEMBL590472 | exo-6-[(Cyclobutyloxy)methyl]-6-(3,...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308253(CHEMBL610795 | exo-6-{[(Cyclopropylmethyl)oxy]meth...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308251((1S,5S,6S)-1-(3,4-Dichlorophenyl)-6-[(ethyloxy)met...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human CYP2CD6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308248(CHEMBL598215 | exo-6-[(Methyloxy)methyl]-1-(2-naph...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of human CYP2CD6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308248(CHEMBL598215 | exo-6-[(Methyloxy)methyl]-1-(2-naph...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308246(CHEMBL598644 | exo-6-(3,4-Dichlorophenyl)-3-azabic...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415478(CHEMBL2021577)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human CYP2CD6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308248(CHEMBL598215 | exo-6-[(Methyloxy)methyl]-1-(2-naph...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308248(CHEMBL598215 | exo-6-[(Methyloxy)methyl]-1-(2-naph...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308251((1S,5S,6S)-1-(3,4-Dichlorophenyl)-6-[(ethyloxy)met...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human ERG assessed as blockade of channel current by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415477(CHEMBL2021582)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415477(CHEMBL2021582)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP2CD6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415477(CHEMBL2021582)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415477(CHEMBL2021582)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308252(CHEMBL596809 | exo-1-(3,4-dichlorophenyl)-6-(metho...)
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308252(CHEMBL596809 | exo-1-(3,4-dichlorophenyl)-6-(metho...)
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308252(CHEMBL596809 | exo-1-(3,4-dichlorophenyl)-6-(metho...)
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308252(CHEMBL596809 | exo-1-(3,4-dichlorophenyl)-6-(metho...)
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308252(CHEMBL596809 | exo-1-(3,4-dichlorophenyl)-6-(metho...)
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of human CYP2CD6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308249(CHEMBL605209 | exo-1-(3,4-Dichlorophenyl)-6-{[(1-m...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308249(CHEMBL605209 | exo-1-(3,4-Dichlorophenyl)-6-{[(1-m...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308249(CHEMBL605209 | exo-1-(3,4-Dichlorophenyl)-6-{[(1-m...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human CYP2CD6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308249(CHEMBL605209 | exo-1-(3,4-Dichlorophenyl)-6-{[(1-m...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308249(CHEMBL605209 | exo-1-(3,4-Dichlorophenyl)-6-{[(1-m...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308251((1S,5S,6S)-1-(3,4-Dichlorophenyl)-6-[(ethyloxy)met...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415478(CHEMBL2021577)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308251((1S,5S,6S)-1-(3,4-Dichlorophenyl)-6-[(ethyloxy)met...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415478(CHEMBL2021577)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415478(CHEMBL2021577)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308251((1S,5S,6S)-1-(3,4-Dichlorophenyl)-6-[(ethyloxy)met...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308251((1S,5S,6S)-1-(3,4-Dichlorophenyl)-6-[(ethyloxy)met...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308245(CHEMBL590472 | exo-6-[(Cyclobutyloxy)methyl]-6-(3,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308245(CHEMBL590472 | exo-6-[(Cyclobutyloxy)methyl]-6-(3,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308245(CHEMBL590472 | exo-6-[(Cyclobutyloxy)methyl]-6-(3,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2CD6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308245(CHEMBL590472 | exo-6-[(Cyclobutyloxy)methyl]-6-(3,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308246(CHEMBL598644 | exo-6-(3,4-Dichlorophenyl)-3-azabic...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308253(CHEMBL610795 | exo-6-{[(Cyclopropylmethyl)oxy]meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308246(CHEMBL598644 | exo-6-(3,4-Dichlorophenyl)-3-azabic...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308253(CHEMBL610795 | exo-6-{[(Cyclopropylmethyl)oxy]meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308253(CHEMBL610795 | exo-6-{[(Cyclopropylmethyl)oxy]meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308246(CHEMBL598644 | exo-6-(3,4-Dichlorophenyl)-3-azabic...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed