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PubMed code 20303751

Compile data set for download or QSAR
Found 4 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cystine/glutamate transporter


(Homo sapiens)
BDBM50053588
PNG
((S)-4-(amino(carboxy)methyl)benzoic acid | (S)-4-c...)
Show SMILES N[C@H](C(O)=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C9H9NO4/c10-7(9(13)14)5-1-3-6(4-2-5)8(11)12/h1-4,7H,10H2,(H,11,12)(H,13,14)/t7-/m0/s1
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PC cid
PC sid
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Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



The University of Montana

Curated by ChEMBL


Assay Description
Inhibition of amino acid transport system xc-


Bioorg Med Chem Lett 20: 2680-3 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.020
BindingDB Entry DOI: 10.7270/Q29Z952F
More data for this
Ligand-Target Pair
Cystine/glutamate transporter


(Homo sapiens)
BDBM17660
PNG
((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Show SMILES N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O
Show InChI InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1
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KEGG
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PC cid
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Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



The University of Montana

Curated by ChEMBL


Assay Description
Inhibition of amino acid transport system xc-


Bioorg Med Chem Lett 20: 2680-3 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.020
BindingDB Entry DOI: 10.7270/Q29Z952F
More data for this
Ligand-Target Pair
Cystine/glutamate transporter


(Homo sapiens)
BDBM17663
PNG
((2S)-2-amino-3-(sulfooxy)propanoic acid | L-SOS | ...)
Show SMILES N[C@@H](COS(O)(=O)=O)C(O)=O
Show InChI InChI=1S/C3H7NO6S/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1
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MMDB
PC cid
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Article
PubMed
n/an/a 2.60E+4n/an/an/an/an/an/a



The University of Montana

Curated by ChEMBL


Assay Description
Inhibition of amino acid transport system xc-


Bioorg Med Chem Lett 20: 2680-3 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.020
BindingDB Entry DOI: 10.7270/Q29Z952F
More data for this
Ligand-Target Pair
Cystine/glutamate transporter


(Homo sapiens)
BDBM50220147
PNG
((S)-2-amino-4-sulfobutanoic acid | CHEMBL230951 | ...)
Show SMILES N[C@@H](CCS(O)(=O)=O)C(O)=O
Show InChI InChI=1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)/t3-/m0/s1
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CHEMBL
KEGG
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 3.50E+4n/an/an/an/an/an/a



The University of Montana

Curated by ChEMBL


Assay Description
Inhibition of amino acid transport system xc-


Bioorg Med Chem Lett 20: 2680-3 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.020
BindingDB Entry DOI: 10.7270/Q29Z952F
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%