Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 50031740
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318213((Z)-3-(5-((7-(3-Nitrophenyl)-9-oxo-5H-benzo[h]thia...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318190((Z)-3-((2-Methoxy-4-((7-(4-methoxyphenyl)-9-oxo-5H...)
Affinity DataIC50:  3.00E+3nMAssay Description:Displacement of FITC-labeled BH3 peptide from human Bcl-XL after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318191((Z)-3-(5-((7-(3-Fluorophenyl)-9-oxo-5H-benzo[h]thi...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318189((Z)-2-(3-((7-(2-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  3.10E+3nMAssay Description:Displacement of FITC labeled BH3 peptide from His-tagged human BCL2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318190((Z)-3-((2-Methoxy-4-((7-(4-methoxyphenyl)-9-oxo-5H...)
Affinity DataIC50:  3.20E+3nMAssay Description:Displacement of FITC labeled BH3 peptide from His-tagged human BCL2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318189((Z)-2-(3-((7-(2-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  3.40E+3nMAssay Description:Displacement of FITC-labeled BH3 peptide from human Bcl-XL after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318189((Z)-2-(3-((7-(2-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318212((Z)-3-(5-((7-(4-Fluorophenyl)-9-oxo-5H-benzo[h]thi...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318200((Z)-3-(5-((7-(2-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318202((Z)-2-(3-((7-(3-Fluorophenyl)-9-oxo-5H-benzo[h]thi...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318211((Z)-3-(5-((7-(2-Fluorophenyl)-9-oxo-5H-benzo[h]thi...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318218((Z)-2-(5-(4-bromobenzylidene)-4-oxo-2-thioxotetrah...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318189((Z)-2-(3-((7-(2-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  6.40E+3nMAssay Description:Displacement of FITC-labeled BH3 peptide from GST-tagged mouse Mcl1 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318192((Z)-3-(4-((7-(4-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318191((Z)-3-(5-((7-(3-Fluorophenyl)-9-oxo-5H-benzo[h]thi...)
Affinity DataIC50:  6.90E+3nMAssay Description:Displacement of FITC-labeled BH3 peptide from human Bcl-XL after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318193((Z)-3-(4-((7-(3-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318192((Z)-3-(4-((7-(4-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  7.30E+3nMAssay Description:Displacement of FITC-labeled BH3 peptide from human Bcl-XL after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318191((Z)-3-(5-((7-(3-Fluorophenyl)-9-oxo-5H-benzo[h]thi...)
Affinity DataIC50:  8.00E+3nMAssay Description:Displacement of FITC labeled BH3 peptide from His-tagged human BCL2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318190((Z)-3-((2-Methoxy-4-((7-(4-methoxyphenyl)-9-oxo-5H...)
Affinity DataIC50:  8.60E+3nMAssay Description:Displacement of FITC-labeled BH3 peptide from GST-tagged mouse Mcl1 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318201((Z)-2-(3-((9-Oxo-7-phenyl)-5H-benzo[h]thiazolo[2,3...)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318192((Z)-3-(4-((7-(4-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  1.11E+4nMAssay Description:Displacement of FITC labeled BH3 peptide from His-tagged human BCL2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318195((Z)-2-(2-((7-(2-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  1.21E+4nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318198((Z)-4-((7-(2-Methoxyphenyl)-9-oxo-5H-benzo[h]thiaz...)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318210((Z)-3-(5-((9-Oxo-7-phenyl-5H-benzo[h]thiazolo[2,3-...)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318197((Z)-3-(4-((E)-(7-(2-Methoxyphenyl)-9-oxo-5H-benzo[...)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318214((Z)-3-(5-((7-(Naphthalen-1-yl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318193((Z)-3-(4-((7-(3-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  1.74E+4nMAssay Description:Displacement of FITC-labeled BH3 peptide from human Bcl-XL after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318190((Z)-3-((2-Methoxy-4-((7-(4-methoxyphenyl)-9-oxo-5H...)
Affinity DataIC50:  1.74E+4nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318191((Z)-3-(5-((7-(3-Fluorophenyl)-9-oxo-5H-benzo[h]thi...)
Affinity DataIC50:  1.86E+4nMAssay Description:Displacement of FITC-labeled BH3 peptide from GST-tagged mouse Mcl1 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318192((Z)-3-(4-((7-(4-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  1.92E+4nMAssay Description:Displacement of FITC-labeled BH3 peptide from GST-tagged mouse Mcl1 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318193((Z)-3-(4-((7-(3-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  1.94E+4nMAssay Description:Displacement of FITC labeled BH3 peptide from His-tagged human BCL2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318203((Z)-2-(3-((7-(Naphthalen-1-yl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318199((Z)-30-((7-(2-Methoxyphenyl)-9-oxo-5H-benzo[h]thia...)
Affinity DataIC50:  2.67E+4nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318193((Z)-3-(4-((7-(3-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  3.44E+4nMAssay Description:Displacement of FITC-labeled BH3 peptide from GST-tagged mouse Mcl1 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318215((Z)-3-(5-((7-(Furan-2-yl)-9-oxo-5H-benzo[h]thiazol...)
Affinity DataIC50:  3.59E+4nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318196((Z)-2-(4-((7-(2-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318204((Z)-2-(3-((7-(Furan-2-yl)-9-oxo-5H-benzo[h]thiazol...)
Affinity DataIC50:  4.04E+4nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318209((Z)-2-(3-((5-(2-Methoxyphenyl)-3-oxo-7-phenyl-3,5-...)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318217(3-(5-((Z)-((E)-9-(3-Fluorobenzylidene)-5-(3-fluoro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318216((Z)-3-(4-((7-(3-Fluorophenyl)-3-methoxy-9-oxo-5H-b...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318194((Z)-Ethyl-2-(3-((7-(2-methoxyphenyl)-9-oxo-5H-benz...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318208(2-(3-((Z)-((E)-9-(3-Fluorobenzylidene)-5-(3-fluoro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318207((Z)-2-(3-((4-(Biphenylcarbonyloxy)-7-(2-methoxyphe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318205((Z)-2-(3-((3-Methoxy-7-(2-methoxyphenyl)-9-oxo-5H-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318206((Z)-2-(3-((4-(Benzyloxy)-7-(2-methoxyphenyl)-9-oxo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318189((Z)-2-(3-((7-(2-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataKd:  9.50E+3nMAssay Description:Binding affinity to human Bcl-XL by surface plasma resonance based biosensor systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318190((Z)-3-((2-Methoxy-4-((7-(4-methoxyphenyl)-9-oxo-5H...)
Affinity DataKd:  9.63E+4nMAssay Description:Binding affinity to human Bcl-XL by surface plasma resonance based biosensor systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50318192((Z)-3-(4-((7-(4-Methoxyphenyl)-9-oxo-5H-benzo[h]th...)
Affinity DataKd:  3.85E+4nMAssay Description:Binding affinity to human Bcl-XL by surface plasma resonance based biosensor systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed