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Found 7 Enz. Inhib. hit(s) with all data for entry = 50031976
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  750nMAssay Description:Inhibition of human recombinant COX2 assessed as PGE2 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50322615(CHEMBL1173685 | CHEMBL1823816 | Resveratrol Potass...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of sheep seminal vesicles COX1 assessed as PGE2 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50322614(CHEMBL1173450 | Resveratrol Potassium4,-Sulfate)
Affinity DataIC50:  5.55E+3nMAssay Description:Inhibition of sheep seminal vesicles COX1 assessed as PGE2 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Purdue University

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  6.65E+3nMAssay Description:Inhibition of sheep seminal vesicles COX1 assessed as PGE2 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50322615(CHEMBL1173685 | CHEMBL1823816 | Resveratrol Potass...)
Affinity DataIC50:  7.53E+3nMAssay Description:Inhibition of human recombinant COX2 assessed as PGE2 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50322614(CHEMBL1173450 | Resveratrol Potassium4,-Sulfate)
Affinity DataIC50:  8.95E+3nMAssay Description:Inhibition of human recombinant COX2 assessed as PGE2 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Purdue University

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse RAW 264.7 cells pretreated 30 mins before LPS challenge measured after 20...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed