Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 50039235
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322288(4-(4-{[(3S)-1-Butyl-3-(cyclohexylmethyl)-2,5-dioxo...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322271(CHEMBL1173007 | rac-1-Butyl-3-(cyclohexylmethyl)-9...)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190516((RS)-1-butyl-3-(cyclohexylmethyl)-9-(4-phenoxybenz...)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322287(4-(4-{[(3S)-1-Butyl-3-(cyclohexylmethyl)-2,5-dioxo...)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322285(4-(4-{[(3S)-1-Butyl-3-(cyclohexylmethyl)-2,5-dioxo...)
Affinity DataIC50:  33nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322273(CHEMBL1173133 | rac-1-Butyl-3-(cyclohexylmethyl)-9...)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322286(CHEMBL1170876 | N-[4-(4-{[(3S)-1-Butyl-3-(cyclohex...)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322284((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(4-hydroxyp...)
Affinity DataIC50:  42nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322262(CHEMBL1171291 | rac-1-Butyl-9-(4-phenoxybenzyl)-3-...)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322263(CHEMBL1170694 | rac-1-Butyl-3-(cyclopentylmethyl)-...)
Affinity DataIC50:  52nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322259(CHEMBL1171096 | rac-1-(2-Butynyl)-3-isobutyl-9-(4-...)
Affinity DataIC50:  54nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322280(4-{[(3S)-1-Butyl-3-(cyclohexylmethyl)-2,5-dioxo-1,...)
Affinity DataIC50:  57nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322258(CHEMBL1171095 | rac-1-[(2E)-2-Butenyl]-3-isobutyl-...)
Affinity DataIC50:  69nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322272((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[(6-phenylpyri...)
Affinity DataIC50:  71nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322282((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(4-methylph...)
Affinity DataIC50:  79nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322261((3S)-1-Butyl-3-neopentyl-9-(4-phenoxybenzyl)-1,4,9...)
Affinity DataIC50:  79nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322279((3S)-9-(4-Benzoylbenzyl)-1-butyl-3-(cyclohexylmeth...)
Affinity DataIC50:  81nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50198940((3S)-1-Butyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-...)
Affinity DataIC50:  84nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322278((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(phenylsulf...)
Affinity DataIC50:  86nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322281((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(4-fluoroph...)
Affinity DataIC50:  92nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190520((RS)-1-butyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-...)
Affinity DataIC50:  94nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190525((RS)-1-butyl-3-(cyclohexylmethyl)-9-(4-methoxybenz...)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50198937((3R)-1-Butyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-...)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322283((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(4-methoxyp...)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322274(CHEMBL1173134 | rac-1-Butyl-3-(cyclohexylmethyl)-9...)
Affinity DataIC50:  160nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322277((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(phenylsulf...)
Affinity DataIC50:  170nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190518(1-butyl-3-(2-methylpropyl)-9-(6-phenylhexyl)-1,4,9...)
Affinity DataIC50:  270nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322260(CHEMBL1171289 | rac-1-Benzyl-3-isobutyl-9-(4-pheno...)
Affinity DataIC50:  300nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322264(CHEMBL1171103 | rac-1-Butyl-3-(methoxymethyl)-9-(4...)
Affinity DataIC50:  320nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322256(CHEMBL1170471 | rac-1,3-Diisobutyl-9-(4-phenoxyben...)
Affinity DataIC50:  330nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322275((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[(5-methyl-2-p...)
Affinity DataIC50:  450nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190524(3-(2-methylpropyl)-9-(4-phenoxyphenylmethyl)-1-pro...)
Affinity DataIC50:  500nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322276(CHEMBL1172870 | rac-1-Butyl-3-(cyclohexylmethyl)-9...)
Affinity DataIC50:  570nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322266(CHEMBL1170660 | rac-Benzyl [1-butyl-2,5-dioxo-9-(4...)
Affinity DataIC50:  590nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190522((RS)-9-benzyl-1-butyl-3-isobutyl-1,4,9-triazaspiro...)
Affinity DataIC50:  900nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322265(CHEMBL1173204 | rac-[1-Butyl-2,5-dioxo-9-(4-phenox...)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322267(CHEMBL1170661 | rac-1-Butyl-3-(3-cyclohexylpropyl)...)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322257(1-(3-hydroxy-butyl)-3-isobutyl-9-(4-phenoxy-benzyl...)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322270(CHEMBL1173708 | rac-Benzyl 1-butyl-3-(cyclohexylme...)
Affinity DataIC50:  3.00E+3nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322269(CHEMBL1173707 | rac-Ethyl 4-[1-butyl-3-(cyclohexyl...)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322268((3S)-1-Butyl-3-(cyclohexylmethyl)-9-[2-(4-phenoxyp...)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed