Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50031992
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322858((R)-3-phenyl-N-((R)-6-(3-(pyrrolidin-1-yl)prop-1-e...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322857((R)-3-phenyl-N-((R)-6-(3-(piperidin-1-yl)prop-1-en...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322868((R)-N-((R)-6-(3-(cyclobutylamino)prop-1-en-2-yl)-1...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322859((R)-N-((R)-6-(3-((S)-3-hydroxypyrrolidin-1-yl)prop...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322867((R)-N-((R)-6-(3-(isopropylamino)prop-1-en-2-yl)-1,...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322866((R)-N-((R)-6-(3-(tert-butylamino)prop-1-en-2-yl)-1...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322861((R)-N-((R)-6-(3-(azetidin-1-yl)prop-1-en-2-yl)-1,2...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322860((R)-N-((R)-6-(3-((R)-3-hydroxypyrrolidin-1-yl)prop...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322856((R)-3-phenyl-N-((R)-6-(1-(piperidin-1-ylmethyl)cyc...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322865((R)-N-((R)-6-(3-(cyclopropylmethylamino)prop-1-en-...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322863((R)-N-((R)-6-(3-(2-hydroxyethylamino)prop-1-en-2-y...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322869((R)-N-((R)-6-(3-(cyclopentylamino)prop-1-en-2-yl)-...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322855((3R)-3-phenyl-N-((1R)-6-(1-(piperidin-1-yl)propan-...)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322864((R)-N-((R)-6-(3-(2-methoxyethylamino)prop-1-en-2-y...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322862((R)-N-((R)-6-(3-(dimethylamino)prop-1-en-2-yl)-1,2...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322870((R)-3-(4-fluorophenyl)-N-((R)-6-(3-(pyrrolidin-1-y...)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322859((R)-N-((R)-6-(3-((S)-3-hydroxypyrrolidin-1-yl)prop...)
Affinity DataIC50:  3.90nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322858((R)-3-phenyl-N-((R)-6-(3-(pyrrolidin-1-yl)prop-1-e...)
Affinity DataIC50:  9.70nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322860((R)-N-((R)-6-(3-((R)-3-hydroxypyrrolidin-1-yl)prop...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322864((R)-N-((R)-6-(3-(2-methoxyethylamino)prop-1-en-2-y...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322863((R)-N-((R)-6-(3-(2-hydroxyethylamino)prop-1-en-2-y...)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322857((R)-3-phenyl-N-((R)-6-(3-(piperidin-1-yl)prop-1-en...)
Affinity DataIC50:  41nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322867((R)-N-((R)-6-(3-(isopropylamino)prop-1-en-2-yl)-1,...)
Affinity DataIC50:  42nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322868((R)-N-((R)-6-(3-(cyclobutylamino)prop-1-en-2-yl)-1...)
Affinity DataIC50:  44nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322869((R)-N-((R)-6-(3-(cyclopentylamino)prop-1-en-2-yl)-...)
Affinity DataIC50:  47nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322866((R)-N-((R)-6-(3-(tert-butylamino)prop-1-en-2-yl)-1...)
Affinity DataIC50:  78nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322856((R)-3-phenyl-N-((R)-6-(1-(piperidin-1-ylmethyl)cyc...)
Affinity DataIC50:  88nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322865((R)-N-((R)-6-(3-(cyclopropylmethylamino)prop-1-en-...)
Affinity DataIC50:  105nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322862((R)-N-((R)-6-(3-(dimethylamino)prop-1-en-2-yl)-1,2...)
Affinity DataIC50:  154nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322861((R)-N-((R)-6-(3-(azetidin-1-yl)prop-1-en-2-yl)-1,2...)
Affinity DataIC50:  206nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322855((3R)-3-phenyl-N-((1R)-6-(1-(piperidin-1-yl)propan-...)
Affinity DataIC50:  316nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed