Compile Data Set for Download or QSAR
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Found 37 Enz. Inhib. hit(s) with all data for entry = 50032387
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataIC50:  3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328416((Z)-3-((4-(3-(dimethylamino)propoxy)-3-methylazule...)
Affinity DataIC50:  5nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328417((Z)-4,5-difluoro-3-((3-methyl-4-(3-morpholinopropo...)
Affinity DataIC50:  12nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328406((Z)-3-((4-(3-(dimethylamino)propoxy)-3-methylazule...)
Affinity DataIC50:  12nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328419((Z)-3-((4-(3-(diethylamino)propoxy)-3-methylazulen...)
Affinity DataIC50:  14nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataIC50:  15nMAssay Description:Inhibition of c-Kit autophosphorylation in human Kasumi-1 cells by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataIC50:  16nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataIC50:  17nMAssay Description:Inhibition of PDGFRbeta autophosphorylation by cell based western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328418((Z)-4,5-difluoro-3-((3-methyl-4-(3-(piperidin-1-yl...)
Affinity DataIC50:  17nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328415((Z)-3-((4-(2-(4-(dimethylamino)piperidin-1-yl)etho...)
Affinity DataIC50:  18nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328403((Z)-5-fluoro-3-((3-methyl-4-(2-morpholinoethoxy)az...)
Affinity DataIC50:  19nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328401((Z)-5-fluoro-3-((3-fluoroazulen-1-yl)methylene)ind...)
Affinity DataIC50:  23nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328405((E)-3-((4-(3-(dimethylamino)propoxy)-3-methylazule...)
Affinity DataIC50:  25nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328414(CHEMBL1258603 | E/Z-(S)-5-fluoro-3-((4-(2-(2-(hydr...)
Affinity DataIC50:  28nMAssay Description:Inhibition of PDGFRbeta autophosphorylation by cell based western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328407((E)-3-((4-(3-(diethylamino)propoxy)-3-methylazulen...)
Affinity DataIC50:  30nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328408((Z)-3-((4-(3-(diethylamino)propoxy)-3-methylazulen...)
Affinity DataIC50:  39nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328414(CHEMBL1258603 | E/Z-(S)-5-fluoro-3-((4-(2-(2-(hydr...)
Affinity DataIC50:  44nMAssay Description:Inhibition of c-Kit autophosphorylation in human Kasumi-1 cells by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataIC50:  53nMAssay Description:Inhibition of KDR autophosphorylation in HUVEC by Western blot analysisMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328399((E)-5-fluoro-3-((3-methylazulen-1-yl)methylene)ind...)
Affinity DataIC50:  60nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328414(CHEMBL1258603 | E/Z-(S)-5-fluoro-3-((4-(2-(2-(hydr...)
Affinity DataIC50:  70nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328411((Z)-5-bromo-3-((3-methyl-4-(3-morpholinopropoxy)az...)
Affinity DataIC50:  86nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328410((Z)-5-fluoro-3-((3-methyl-4-(3-morpholinopropoxy)a...)
Affinity DataIC50:  90nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328414(CHEMBL1258603 | E/Z-(S)-5-fluoro-3-((4-(2-(2-(hydr...)
Affinity DataIC50:  98nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328400((Z)-5-fluoro-3-((3-methylazulen-1-yl)methylene)ind...)
Affinity DataIC50:  128nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328413((E)-3-((4-(3-(dimethylamino)propoxy)-3-methylazule...)
Affinity DataIC50:  177nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328414(CHEMBL1258603 | E/Z-(S)-5-fluoro-3-((4-(2-(2-(hydr...)
Affinity DataIC50:  186nMAssay Description:Inhibition of KDR autophosphorylation in HUVEC by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328404((Z)-5-fluoro-3-((3-methyl-4-(3-morpholinopropoxy)a...)
Affinity DataIC50:  224nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328392(3-(azulen-1-ylmethylene)indolin-2-one | CHEMBL1257...)
Affinity DataIC50:  470nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328412((E)-3-((4-(3-(dimethylamino)propoxy)-3-methylazule...)
Affinity DataIC50:  742nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328395((Z)-3-(azulen-1-ylmethylene)-5-bromoindolin-2-one ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328394((E)-3-(azulen-1-ylmethylene)-5-bromoindolin-2-one ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328393((Z)-3-(azulen-1-ylmethylene)-5-fluoroindolin-2-one...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328396((Z)-3-(azulen-1-ylmethylene)-5-methylindolin-2-one...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328402((Z)-3-(azulen-1-ylmethylene)-N,N-dimethyl-2-oxoind...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328398((Z)-3-((3-methylazulen-1-yl)methylene)indolin-2-on...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328397((E)-3-((3-methylazulen-1-yl)methylene)indolin-2-on...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328409((Z)-3-((4-(3-(dimethylamino)propoxy)-3-methylazule...)
Affinity DataIC50:  1.46E+3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed