Compile Data Set for Download or QSAR
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Found 27 Enz. Inhib. hit(s) with all data for entry = 50033631
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348708(CHEMBL1801440)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348706(CHEMBL1801411)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348707(CHEMBL1801439)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348701(CHEMBL1801434)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348708(CHEMBL1801440)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of catalytic domain of SHP-1 expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348692(CHEMBL1801404)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348695(CHEMBL1801407)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348702(CHEMBL1801435)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348697(CHEMBL1801409)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348690(CHEMBL1801402)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348694(CHEMBL1801406)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348693(CHEMBL1801405)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348689(CHEMBL1801401)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348688(CHEMBL1801400)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348704(CHEMBL1801437)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348699(CHEMBL1801432)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase 1(Saccharomyces cerevisiae)
Inha University

Curated by ChEMBL
LigandPNGBDBM50348708(CHEMBL1801440)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of yeast PTP1 expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348700(CHEMBL1801433)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348705(CHEMBL1801438)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348691(CHEMBL1801403)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348708(CHEMBL1801440)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of TC-PTP assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348698(CHEMBL1801410)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348703(CHEMBL1801436)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348708(CHEMBL1801440)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of membrane proximal catalytic domain of LAR-D1 assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348696(CHEMBL1801408)
Affinity DataIC50:  1.36E+5nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50348708(CHEMBL1801440)
Affinity DataEC50:  340nMAssay Description:Agonist activity at PPARgamma expressed in HepG2 cells co-expressing PPRE assessed as transcriptional activation after 24 hrs by luciferase reporter ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50299153((Z)-5-{2-[3,5-bis(trifluoromethyl)benzyloxy]-5-bro...)
Affinity DataEC50:  870nMAssay Description:Agonist activity at PPARgamma expressed in HepG2 cells co-expressing PPRE assessed as transcriptional activation after 24 hrs by luciferase reporter ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed