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Found 12 Enz. Inhib. hit(s) with all data for entry = 50032463
TargetSqualene synthase(Rattus norvegicus)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50329674(2-[4-(2-Naphthalen)-phenyl]-4-methyl-octahydro-1,4...)
Affinity DataIC50:  800nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50329672(2-[4-(6-Methoxy-2-naphthalen)-phenyl]-4-methyl-oct...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50329673(2-[4-(2-Naphthalen)-phenyl]-4-methylmorpholin-2-ol...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50329670(2-[4-(6-Methoxy-2-naphthalen)-phenyl]-4-methylmorp...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50329669(2-(2-Naphthalene)-4-methyl-octahydro-1,4-benzoxazi...)
Affinity DataIC50:  1.51E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50329671(3-[4-(6-Methoxy-2-naphthalen)-phenyl]-octahydro-1,...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50329665(3-(6-Methoxy-2-naphthalene)-octahydro-1,4-pyrido[2...)
Affinity DataIC50:  1.87E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50213690(2-Biphenyl-4-yl-4-methyl-octahydro-benzo[1,4]oxazi...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50329666(2-(6-Methoxy-2-naphthalene)-4-methyl-octahydro-1,4...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50329668(3-(2-Naphthalene)-octahydro-1,4-pyrido[2,1-c]oxazi...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50329667(2-(2-Naphthalene)-4-methylmorpholin-2-ol hydrobrom...)
Affinity DataIC50:  1.35E+5nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50329664(2-(6-Methoxy-2-naphthalene)-4-methylmorpholin-2-ol...)
Affinity DataIC50:  1.55E+5nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed