Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50032527
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330546(4-Furan-6-methyl-N-(4-methoxyphenyl)-4,7-dihydro-2...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330547(4-Thiophene-6-methyl-N-(4-methoxyphenyl)-4,7-dihyd...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198311((R)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquina...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330548(4-Phenyl-6-methyl-N-(4-fluorophenyl)-4,7-dihydro-2...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330549(4-Phenyl-6-methyl-N-(3-chloro-4-fluorophenyl)-4,7-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330550(CHEMBL1277474 | N-(4-chlorophenyl)-2,7,7-trimethyl...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330551(4-Phenyl-6-methyl-N-(4-nitrophenyl)-4,7-dihydro-2H...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330552(4-Thiophene-6-methyl-N-(4-trifluoromethylphenyl)-4...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330553(4-Phenyl-6-methyl-N-(4-trifluoromethylphenyl)-4,7-...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330554(4-Furan-6-methyl-N-(3-chloro-4-fluorophenyl)-4,7-d...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330555(4-Thiophene-6-methyl-N-(3-chloro-4-fluorophenyl)-4...)
Affinity DataIC50:  440nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330556(4-Thiophene-6-methyl-N-(4-nitrophenyl)-4,7-dihydro...)
Affinity DataIC50:  820nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330557(CHEMBL1277383 | N-(3-Chloro-4-fluorobenzyl)-4-fura...)
Affinity DataIC50:  960nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330558(4-Furan-6-methyl-N-(4-trifluoromethylphenyl)-4,7-d...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330559(CHEMBL1277382 | N-(4-Trifluoromethylbenzyl)-4-fura...)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330560(CHEMBL1277293 | N-(4-Methoxybenzyl)-4-furan-2-meth...)
Affinity DataIC50:  2.46E+3nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330561(4-Furan-6-methyl-N-(4-nitrophenyl)-4,7-dihydro-2Hp...)
Affinity DataIC50:  2.76E+3nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330562(4-Phenyl-6-methyl-N-(4-methoxyphenyl)-4,7-dihydro-...)
Affinity DataIC50:  2.82E+3nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330563(CHEMBL1277294 | N-(4-Nitrobenzyl)-4-furan-2-methyl...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330559(CHEMBL1277382 | N-(4-Trifluoromethylbenzyl)-4-fura...)
Affinity DataIC50:  3.32E+3nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50224731(4-(6-chloro-3H-imidazo[4,5-b]pyridin-2-yl)-N,N-dim...)
Affinity DataIC50:  4.97E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50216502(4-(3-hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4-tet...)
Affinity DataIC50:  5.47E+3nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330564(CHEMBL1277473 | N-(4-Fluorobenzyl)-4-furan-2-methy...)
Affinity DataIC50:  5.65E+3nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330557(CHEMBL1277383 | N-(3-Chloro-4-fluorobenzyl)-4-fura...)
Affinity DataIC50:  5.73E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330564(CHEMBL1277473 | N-(4-Fluorobenzyl)-4-furan-2-methy...)
Affinity DataIC50:  6.15E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330560(CHEMBL1277293 | N-(4-Methoxybenzyl)-4-furan-2-meth...)
Affinity DataIC50:  7.58E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330565(4-Furan-6-methyl-N-(4-fluorophenyl)-4,7-dihydro-2H...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330546(4-Furan-6-methyl-N-(4-methoxyphenyl)-4,7-dihydro-2...)
Affinity DataIC50:  9.25E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330565(4-Furan-6-methyl-N-(4-fluorophenyl)-4,7-dihydro-2H...)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330554(4-Furan-6-methyl-N-(3-chloro-4-fluorophenyl)-4,7-d...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330563(CHEMBL1277294 | N-(4-Nitrobenzyl)-4-furan-2-methyl...)
Affinity DataIC50:  2.09E+4nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50224731(4-(6-chloro-3H-imidazo[4,5-b]pyridin-2-yl)-N,N-dim...)
Affinity DataIC50:  4.02E+4nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330550(CHEMBL1277474 | N-(4-chlorophenyl)-2,7,7-trimethyl...)
Affinity DataIC50:  4.03E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330558(4-Furan-6-methyl-N-(4-trifluoromethylphenyl)-4,7-d...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50216502(4-(3-hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4-tet...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330561(4-Furan-6-methyl-N-(4-nitrophenyl)-4,7-dihydro-2Hp...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330555(4-Thiophene-6-methyl-N-(3-chloro-4-fluorophenyl)-4...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330552(4-Thiophene-6-methyl-N-(4-trifluoromethylphenyl)-4...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330556(4-Thiophene-6-methyl-N-(4-nitrophenyl)-4,7-dihydro...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330547(4-Thiophene-6-methyl-N-(4-methoxyphenyl)-4,7-dihyd...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330548(4-Phenyl-6-methyl-N-(4-fluorophenyl)-4,7-dihydro-2...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330549(4-Phenyl-6-methyl-N-(3-chloro-4-fluorophenyl)-4,7-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330553(4-Phenyl-6-methyl-N-(4-trifluoromethylphenyl)-4,7-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198311((R)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquina...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330562(4-Phenyl-6-methyl-N-(4-methoxyphenyl)-4,7-dihydro-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330551(4-Phenyl-6-methyl-N-(4-nitrophenyl)-4,7-dihydro-2H...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed