Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50032782
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334604(2-(7-(5-chloro-4-(2-methoxy-4-(2-methoxyethoxy)phe...)
Affinity DataIC50:  4nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50:  4nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334595(5-chloro-N2,N4-bis(2-methoxy-4-morpholinophenyl)py...)
Affinity DataIC50:  4nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334601(2-(7-(5-chloro-4-(2-methoxyphenylamino)pyrimidin-2...)
Affinity DataIC50:  4nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50:  5nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334606(2-(7-(5-chloro-4-(2,4-dimethoxyphenylamino)pyrimid...)
Affinity DataIC50:  5nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334602(4-(5-chloro-2-(3-(2-(dimethylamino)-2-oxoethyl)-8-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334603(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50:  6nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334605(2-(7-(5-chloro-4-(4-cyano-2-methoxyphenylamino)pyr...)
Affinity DataIC50:  7nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334597(5-chloro-N2-(8-methoxy-3-(2-methoxyethyl)-2,3,4,5-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334599(5-chloro-N2-(8-methoxy-3-(2-(methylsulfonyl)ethyl)...)
Affinity DataIC50:  10nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50:  25nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50:  30nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334596(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50:  34nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334606(2-(7-(5-chloro-4-(2,4-dimethoxyphenylamino)pyrimid...)
Affinity DataIC50:  40nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334604(2-(7-(5-chloro-4-(2-methoxy-4-(2-methoxyethoxy)phe...)
Affinity DataIC50:  40nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334600(2-(7-(5-chloro-4-(4-morpholinophenylamino)pyrimidi...)
Affinity DataIC50:  49nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50:  50nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334598(5-chloro-N2-(3-(2,2-difluoroethyl)-8-methoxy-2,3,4...)
Affinity DataIC50:  58nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334601(2-(7-(5-chloro-4-(2-methoxyphenylamino)pyrimidin-2...)
Affinity DataIC50:  62nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334602(4-(5-chloro-2-(3-(2-(dimethylamino)-2-oxoethyl)-8-...)
Affinity DataIC50:  65nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334601(2-(7-(5-chloro-4-(2-methoxyphenylamino)pyrimidin-2...)
Affinity DataIC50:  65nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334605(2-(7-(5-chloro-4-(4-cyano-2-methoxyphenylamino)pyr...)
Affinity DataIC50:  65nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334603(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50:  100nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334599(5-chloro-N2-(8-methoxy-3-(2-(methylsulfonyl)ethyl)...)
Affinity DataIC50:  100nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334595(5-chloro-N2,N4-bis(2-methoxy-4-morpholinophenyl)py...)
Affinity DataIC50:  120nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334597(5-chloro-N2-(8-methoxy-3-(2-methoxyethyl)-2,3,4,5-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334596(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50:  175nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334606(2-(7-(5-chloro-4-(2,4-dimethoxyphenylamino)pyrimid...)
Affinity DataIC50:  189nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334605(2-(7-(5-chloro-4-(4-cyano-2-methoxyphenylamino)pyr...)
Affinity DataIC50:  233nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334604(2-(7-(5-chloro-4-(2-methoxy-4-(2-methoxyethoxy)phe...)
Affinity DataIC50:  351nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334600(2-(7-(5-chloro-4-(4-morpholinophenylamino)pyrimidi...)
Affinity DataIC50:  504nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334602(4-(5-chloro-2-(3-(2-(dimethylamino)-2-oxoethyl)-8-...)
Affinity DataIC50:  573nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50:  800nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334595(5-chloro-N2,N4-bis(2-methoxy-4-morpholinophenyl)py...)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334597(5-chloro-N2-(8-methoxy-3-(2-methoxyethyl)-2,3,4,5-...)
Affinity DataIC50:  2.69E+3nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334599(5-chloro-N2-(8-methoxy-3-(2-(methylsulfonyl)ethyl)...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334603(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334598(5-chloro-N2-(3-(2,2-difluoroethyl)-8-methoxy-2,3,4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334596(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334593(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed