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Found 4 Enz. Inhib. hit(s) with all data for entry = 50032791
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
College Of Chemical And Environmental Engineering

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human prostate 5alpha-reductase type 2 assessed as formation dihydrotestosterone from [4-14C] testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
College Of Chemical And Environmental Engineering

Curated by ChEMBL
LigandPNGBDBM50334789((4aS,4bR,10aR,10bS,12aS)-10a,12a-dimethyl-2-oxo-1,...)
Affinity DataIC50:  71nMAssay Description:Inhibition of human prostate 5alpha-reductase type 2 assessed as formation dihydrotestosterone from [4-14C] testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
College Of Chemical And Environmental Engineering

Curated by ChEMBL
LigandPNGBDBM50334790((4aS,4bR,10bS,12aS)-8-hydroxy-12a-methyl-3,4,4a,4b...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human prostate 5alpha-reductase type 2 assessed as formation dihydrotestosterone from [4-14C] testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
College Of Chemical And Environmental Engineering

Curated by ChEMBL
LigandPNGBDBM50334791((4aS,4bR,10bS,12aS)-12a-methyl-2-oxo-1,2,3,4,4a,4b...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human prostate 5alpha-reductase type 2 assessed as formation dihydrotestosterone from [4-14C] testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed