Compile Data Set for Download or QSAR
maximum 50k data
Found 9 Enz. Inhib. hit(s) with all data for entry = 50032737
TargetMacrophage metalloelastase(Homo sapiens (Human))
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333940(4-((4-(4'-acetylbiphenyl-4-yl)-5-fluorothiophene-2...)
Affinity DataIC50:  7nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333942((R)-3-(5-fluoro-4-(4-(pyridin-4-yl)phenyl)thiophen...)
Affinity DataIC50:  13nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333941((R)-3-(4-(4'-acetylbiphenyl-4-yl)-5-fluorothiophen...)
Affinity DataIC50:  24nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333939((R)-N-(3-amino-3-oxo-1-phenylpropyl)-5-fluoro-4-(4...)
Affinity DataIC50:  85nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333937(CHEMBL1644426 | trans-4-((5-fluoro-4-(4-(trifluoro...)
Affinity DataIC50:  140nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333938((R)-3-(5-fluoro-4-(4-(trifluoromethoxy)phenyl)thio...)
Affinity DataIC50:  200nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333934(CHEMBL1644423 | trans-4-((4-(4-(trifluoromethoxy)p...)
Affinity DataIC50:  400nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333935(CHEMBL1644424 | trans-4-((3-(4-(trifluoromethoxy)p...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333936(CHEMBL1644425 | trans-4-((5-(4-(trifluoromethoxy)p...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed