Compile Data Set for Download or QSAR
maximum 50k data
Found 65 Enz. Inhib. hit(s) with all data for entry = 50032712
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333594(4-(Naphthalen-2-ylmethoxy)-1-{4-[2-(pyrrolidin-1-y...)
Affinity DataIC50:  0.670nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333604(1-(4-{2-[Benzyl(methyl)amino]ethoxy}phenyl)-4-(ben...)
Affinity DataIC50:  0.810nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333616(4-[(4-Methoxybenzyl)oxy]-1-{4-[2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50162116(2-(4-(benzyloxy)phenyl)-N-(1-(2-(pyrrolidin-1-yl)e...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333615(4-[(4-Chlorobenzyl)oxy]-1-{4-[2-(pyrrolidin-1-yl)e...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333611(4-(Benzyloxy)-1-(4-{[2-(diethylamino)ethyl](methyl...)
Affinity DataIC50:  1.70nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333615(4-[(4-Chlorobenzyl)oxy]-1-{4-[2-(pyrrolidin-1-yl)e...)
Affinity DataIC50:  1.70nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333618(4-[(3-Chlorobenzyl)oxy]-1-{4-[2-(pyrrolidin-1-yl)e...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333617(1-{4-[2-(Pyrrolidin-1-yl)ethoxy]phenyl}-4-{[4-(tri...)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333614(4-[(3-Fluorobenzyl)oxy]-1-{4-[2-(pyrrolidin-1-yl)e...)
Affinity DataIC50:  2.90nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333604(1-(4-{2-[Benzyl(methyl)amino]ethoxy}phenyl)-4-(ben...)
Affinity DataIC50:  3.80nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333618(4-[(3-Chlorobenzyl)oxy]-1-{4-[2-(pyrrolidin-1-yl)e...)
Affinity DataIC50:  4.20nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333603(4-(Benzyloxy)-1-{4-[2-(diisopropylamino)ethoxy]-ph...)
Affinity DataIC50:  4.30nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333613(4-[(2-Fluorobenzyl)oxy]-1-{4-[2-(pyrrolidin-1-yl)e...)
Affinity DataIC50:  4.30nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333596(4-(Benzyloxy)-1-{4-[2-(piperidin-1-yl)ethoxy]pheny...)
Affinity DataIC50:  4.40nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333603(4-(Benzyloxy)-1-{4-[2-(diisopropylamino)ethoxy]-ph...)
Affinity DataIC50:  5.10nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50150715(4''-Fluoro-biphenyl-4-carboxylic acid (6-dimethyla...)
Affinity DataIC50:  5.5nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301081(4-(4-fluorobenzyloxy)-1-(4-(2-(pyrrolidin-1-yl)eth...)
Affinity DataIC50:  5.60nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333597(4-(Benzyloxy)-1-{4-[2-(pyrrolidin-1-yl)ethoxy]phen...)
Affinity DataIC50:  5.80nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333596(4-(Benzyloxy)-1-{4-[2-(piperidin-1-yl)ethoxy]pheny...)
Affinity DataIC50:  5.80nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333607(4-(Benzyloxy)-1-{4-[(1-methylpiperidin-2-yl)methox...)
Affinity DataIC50:  5.80nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333614(4-[(3-Fluorobenzyl)oxy]-1-{4-[2-(pyrrolidin-1-yl)e...)
Affinity DataIC50:  5.90nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333602(4-(Benzyloxy)-1-{4-[2-(diethylamino)ethoxy]phenyl}...)
Affinity DataIC50:  6.60nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333617(1-{4-[2-(Pyrrolidin-1-yl)ethoxy]phenyl}-4-{[4-(tri...)
Affinity DataIC50:  6.70nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333610(4-(Benzyloxy)-1-(4-{[2-(diethylamino)ethyl]amino}-...)
Affinity DataIC50:  6.80nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333616(4-[(4-Methoxybenzyl)oxy]-1-{4-[2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  7nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333610(4-(Benzyloxy)-1-(4-{[2-(diethylamino)ethyl]amino}-...)
Affinity DataIC50:  7nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333594(4-(Naphthalen-2-ylmethoxy)-1-{4-[2-(pyrrolidin-1-y...)
Affinity DataIC50:  7.70nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333597(4-(Benzyloxy)-1-{4-[2-(pyrrolidin-1-yl)ethoxy]phen...)
Affinity DataIC50:  8.10nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333613(4-[(2-Fluorobenzyl)oxy]-1-{4-[2-(pyrrolidin-1-yl)e...)
Affinity DataIC50:  8.70nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301081(4-(4-fluorobenzyloxy)-1-(4-(2-(pyrrolidin-1-yl)eth...)
Affinity DataIC50:  9nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333608(4-(Benzyloxy)-1-{4-[(1-methylpyrrolidin-2-yl)metho...)
Affinity DataIC50:  9.30nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333601(4-(Benzyloxy)-1-{4-[2-(dimethylamino)ethoxy]phenyl...)
Affinity DataIC50:  9.5nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333602(4-(Benzyloxy)-1-{4-[2-(diethylamino)ethoxy]phenyl}...)
Affinity DataIC50:  9.80nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333609(4-(Benzyloxy)-1-{4-[(1-methylpyrrolidin-3-yl)oxy]-...)
Affinity DataIC50: >10nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333601(4-(Benzyloxy)-1-{4-[2-(dimethylamino)ethoxy]phenyl...)
Affinity DataIC50: >10nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333600(4-(Benzyloxy)-1-{4-[2-(morpholin-4-yl)ethoxy]pheny...)
Affinity DataIC50: >10nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333616(4-[(4-Methoxybenzyl)oxy]-1-{4-[2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333608(4-(Benzyloxy)-1-{4-[(1-methylpyrrolidin-2-yl)metho...)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333620(4-[(2-Chlorobenzyl)oxy]-1-{4-[2-(pyrrolidin-1-yl)e...)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333611(4-(Benzyloxy)-1-(4-{[2-(diethylamino)ethyl](methyl...)
Affinity DataIC50:  16nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333615(4-[(4-Chlorobenzyl)oxy]-1-{4-[2-(pyrrolidin-1-yl)e...)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333609(4-(Benzyloxy)-1-{4-[(1-methylpyrrolidin-3-yl)oxy]-...)
Affinity DataIC50:  18nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333601(4-(Benzyloxy)-1-{4-[2-(dimethylamino)ethoxy]phenyl...)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333607(4-(Benzyloxy)-1-{4-[(1-methylpiperidin-2-yl)methox...)
Affinity DataIC50:  18nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333596(4-(Benzyloxy)-1-{4-[2-(piperidin-1-yl)ethoxy]pheny...)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333614(4-[(3-Fluorobenzyl)oxy]-1-{4-[2-(pyrrolidin-1-yl)e...)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333603(4-(Benzyloxy)-1-{4-[2-(diisopropylamino)ethoxy]-ph...)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301081(4-(4-fluorobenzyloxy)-1-(4-(2-(pyrrolidin-1-yl)eth...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333608(4-(Benzyloxy)-1-{4-[(1-methylpyrrolidin-2-yl)metho...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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