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PubMed code 21226489

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosinase


(Agaricus bisporus (Common mushroom))
BDBM50031467
PNG
(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Show SMILES OCc1cc(=O)c(O)co1
Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
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PC cid
PC sid
PDB
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Article
PubMed
n/an/a 1.02E+4n/an/an/an/an/an/a



Universidad Nacional de Co£?rdoba

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase preincubated for 10 mins before addition of 1.7 mM L-tyrosine measured after 20 mins by spectrophotometric method


J Nat Prod 74: 158-62 (2011)


Article DOI: 10.1021/np1004664
BindingDB Entry DOI: 10.7270/Q2416XB4
More data for this
Ligand-Target Pair
Tyrosinase


(Agaricus bisporus (Common mushroom))
BDBM50339146
PNG
((-)-(2S)-5,7,2'-trihydroxy-8,3'-diprenylflavanone ...)
Show SMILES CC(C)=CCc1cccc([C@@H]2CC(=O)c3c(O)cc(O)c(CC=C(C)C)c3O2)c1O
Show InChI InChI=1S/C25H28O5/c1-14(2)8-10-16-6-5-7-18(24(16)29)22-13-21(28)23-20(27)12-19(26)17(25(23)30-22)11-9-15(3)4/h5-9,12,22,26-27,29H,10-11,13H2,1-4H3/t22-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.85E+4n/an/an/an/an/an/a



Universidad Nacional de Co£?rdoba

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase preincubated for 10 mins before addition of 1.7 mM L-tyrosine measured after 20 mins by spectrophotometric method


J Nat Prod 74: 158-62 (2011)


Article DOI: 10.1021/np1004664
BindingDB Entry DOI: 10.7270/Q2416XB4
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%