Compile Data Set for Download or QSAR
maximum 50k data
Found 68 Enz. Inhib. hit(s) with all data for entry = 50032880
TargetCathepsin S(Mus musculus (Mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336041(1-methyl-6-(4-(2-(1-(oxazol-2-ylmethyl)piperidin-4...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of mouse cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336044(6-(4-(2-(1-((3,5-dimethylisoxazol-4-yl)methyl)pipe...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323253(1-methyl-6-(4-(2-(2-oxopyrrolidin-1-yl)ethoxy)-3-(...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336042(1-methyl-6-(4-(2-(1-methylpiperidin-4-yl)ethoxy)-3...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336041(1-methyl-6-(4-(2-(1-(oxazol-2-ylmethyl)piperidin-4...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323250(1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336043(2-(4-(2-(4-(4-cyano-1-methyl-1H-imidazo[4,5-c]pyri...)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323250(1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...)
Affinity DataIC50:  9nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of lip10 by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336042(1-methyl-6-(4-(2-(1-methylpiperidin-4-yl)ethoxy)-3...)
Affinity DataIC50:  10nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of lip10 by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336044(6-(4-(2-(1-((3,5-dimethylisoxazol-4-yl)methyl)pipe...)
Affinity DataIC50:  12nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of lip10 by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336047(6-(4-(2-(1-acetylpiperidin-4-yl)ethoxy)-3-(trifluo...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336045(1-methyl-6-(4-(2-(1-((5-methyl-1,3,4-oxadiazol-2-y...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336046(1-methyl-6-(4-(2-(1-((3-methyl-1,2,4-oxadiazol-5-y...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336043(2-(4-(2-(4-(4-cyano-1-methyl-1H-imidazo[4,5-c]pyri...)
Affinity DataIC50:  22nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of lip10 by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336048(1-methyl-6-(4-(2-(1-(methylsulfonyl)piperidin-4-yl...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336041(1-methyl-6-(4-(2-(1-(oxazol-2-ylmethyl)piperidin-4...)
Affinity DataIC50:  39nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of lip10 by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323247(6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)
Affinity DataIC50:  63nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of lip10 by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323247(6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...)
Affinity DataIC50:  84nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of lip10 by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336045(1-methyl-6-(4-(2-(1-((5-methyl-1,3,4-oxadiazol-2-y...)
Affinity DataIC50:  123nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of lip10 by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323250(1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...)
Affinity DataIC50:  178nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336047(6-(4-(2-(1-acetylpiperidin-4-yl)ethoxy)-3-(trifluo...)
Affinity DataIC50:  235nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of lip10 by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336044(6-(4-(2-(1-((3,5-dimethylisoxazol-4-yl)methyl)pipe...)
Affinity DataIC50:  288nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336046(1-methyl-6-(4-(2-(1-((3-methyl-1,2,4-oxadiazol-5-y...)
Affinity DataIC50:  294nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of lip10 by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)
Affinity DataIC50:  331nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336048(1-methyl-6-(4-(2-(1-(methylsulfonyl)piperidin-4-yl...)
Affinity DataIC50:  353nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of lip10 by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336043(2-(4-(2-(4-(4-cyano-1-methyl-1H-imidazo[4,5-c]pyri...)
Affinity DataIC50:  407nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336041(1-methyl-6-(4-(2-(1-(oxazol-2-ylmethyl)piperidin-4...)
Affinity DataIC50:  708nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323247(6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...)
Affinity DataIC50:  776nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336045(1-methyl-6-(4-(2-(1-((5-methyl-1,3,4-oxadiazol-2-y...)
Affinity DataIC50:  813nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336046(1-methyl-6-(4-(2-(1-((3-methyl-1,2,4-oxadiazol-5-y...)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323253(1-methyl-6-(4-(2-(2-oxopyrrolidin-1-yl)ethoxy)-3-(...)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of lip10 by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336047(6-(4-(2-(1-acetylpiperidin-4-yl)ethoxy)-3-(trifluo...)
Affinity DataIC50:  1.91E+3nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336048(1-methyl-6-(4-(2-(1-(methylsulfonyl)piperidin-4-yl...)
Affinity DataIC50:  2.34E+3nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336045(1-methyl-6-(4-(2-(1-((5-methyl-1,3,4-oxadiazol-2-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336046(1-methyl-6-(4-(2-(1-((3-methyl-1,2,4-oxadiazol-5-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336047(6-(4-(2-(1-acetylpiperidin-4-yl)ethoxy)-3-(trifluo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336048(1-methyl-6-(4-(2-(1-(methylsulfonyl)piperidin-4-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323247(6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin VMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin VMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323250(1-methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(triflu...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin VMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336042(1-methyl-6-(4-(2-(1-methylpiperidin-4-yl)ethoxy)-3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin VMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336043(2-(4-(2-(4-(4-cyano-1-methyl-1H-imidazo[4,5-c]pyri...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin VMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336044(6-(4-(2-(1-((3,5-dimethylisoxazol-4-yl)methyl)pipe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin VMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336041(1-methyl-6-(4-(2-(1-(oxazol-2-ylmethyl)piperidin-4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin VMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336045(1-methyl-6-(4-(2-(1-((5-methyl-1,3,4-oxadiazol-2-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin VMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336046(1-methyl-6-(4-(2-(1-((3-methyl-1,2,4-oxadiazol-5-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin VMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336047(6-(4-(2-(1-acetylpiperidin-4-yl)ethoxy)-3-(trifluo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin VMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336048(1-methyl-6-(4-(2-(1-(methylsulfonyl)piperidin-4-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cathepsin VMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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