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Found 9 Enz. Inhib. hit(s) with all data for entry = 50032927
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataIC50:  19nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50063544(1-(6-(methylthio)naphthalen-2-yl)propan-2-amine | ...)
Affinity DataIC50:  200nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataIC50:  900nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50010588((RS)-3,4-(methylenedioxy)methamphetamine | 1-(1,3-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50336553(1,3-bis(3,4-methylenedioxyphenyl)-2-propamine | CH...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50336555(1,3-Bis(4-chlorophenyl)-2-propanamine | CHEMBL1672...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50336556(2-N-Ethylamino-1,3-di(4-methylthiophenyl)propane |...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50336554(1,3-bis(4-(methylthio)phenyl)propan-2-amine | 2-Am...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50336557(2-N-Formylamino-1,3-di(4-methylthiophenyl)propane ...)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed