Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50033371
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Joseph Fourier-Grenoble 1/Cnrs

Curated by ChEMBL
LigandPNGBDBM50343996(2,4-dimethylpyrido[1,2-a]pyrimidin-5-ium-3-olate |...)
Affinity DataIC50:  5nMAssay Description:Inhibition of wild type CFTR expressed in CHO cells by [125I]iodide efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Joseph Fourier-Grenoble 1/Cnrs

Curated by ChEMBL
LigandPNGBDBM50343998((2S,3R,4R)-3,4-dihydroxy-2,4-dimethyl-3,4-dihydro-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of wild type CFTR expressed in CHO cells by [125I]iodide efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Joseph Fourier-Grenoble 1/Cnrs

Curated by ChEMBL
LigandPNGBDBM50343998((2S,3R,4R)-3,4-dihydroxy-2,4-dimethyl-3,4-dihydro-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of wild type CFTR expressed in CHO cells by [125I]iodide efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Joseph Fourier-Grenoble 1/Cnrs

Curated by ChEMBL
LigandPNGBDBM50343997(2,4-dimethylpyrimido[2,1-a]isoquinolin-5-ium-3-ola...)
Affinity DataIC50:  16nMAssay Description:Inhibition of wild type CFTR expressed in CHO cells by [125I]iodide efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Joseph Fourier-Grenoble 1/Cnrs

Curated by ChEMBL
LigandPNGBDBM50012957(1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfon...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of wild type CFTR expressed in CHO cells by [125I]iodide efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed