Compile Data Set for Download or QSAR
maximum 50k data
Found 147 Enz. Inhib. hit(s) with all data for entry = 50033156
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM10246((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM10246((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340533((S)-1-(4-(2-fluoroethoxy)benzyl)-5-(2-((pyridin-3-...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340530((S)-1-(4-methoxybenzyl)-5-(2-((pyridin-3-yloxy)met...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340529((S)-1-(4-(2-fluoroethoxy)benzyl)-5-(2-((pyridin-3-...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340543((S)-1-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)me...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340547((4S,7S,10S,13S)-4-sec-butyl-7-(2-carboxyethyl)-13-...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of caspase 8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340543((S)-1-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)me...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340542((S)-1-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)me...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340537((S)-2-(1-(4-methoxybenzyl)-2-oxo-5-(2-((pyridin-3-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340542((S)-1-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)me...)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340536((S)-2-(1-(4-(2-fluoroethoxy)benzyl)-2-oxo-5-(2-((p...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340540((S)-2-(1-(4-(2-fluoroethoxy)benzyl)-2-oxo-5-(2-((p...)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340548((4S,7S,10S,13S)-10-sec-butyl-7-(2-carboxyethyl)-13...)
Affinity DataIC50:  8nMAssay Description:Inhibition of caspase 6 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM10355((3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-acetamido-3-(4-hydr...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of caspase 1 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340526((S)-1-(4-(2-fluoroethoxy)benzyl)-5-(2-(phenoxymeth...)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340530((S)-1-(4-methoxybenzyl)-5-(2-((pyridin-3-yloxy)met...)
Affinity DataIC50:  10.2nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50273338((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataIC50:  10.8nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340531((S)-1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-5-(2-(p...)
Affinity DataIC50:  10.9nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340541((S)-1-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)me...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340533((S)-1-(4-(2-fluoroethoxy)benzyl)-5-(2-((pyridin-3-...)
Affinity DataIC50:  11.3nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50273338((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataIC50:  11.6nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340531((S)-1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-5-(2-(p...)
Affinity DataIC50:  11.9nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340544((S)-5-(2-((2,4-difluorophenoxy)methyl)azetidin-1-y...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50273337((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataIC50:  12.2nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340545((S)-5-(2-((2,4-difluorophenoxy)methyl)pyrrolidin-1...)
Affinity DataIC50:  12.3nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50273337((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataIC50:  12.4nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340546((S)-5-(2-((2,4-difluorophenoxy)methyl)azetidin-1-y...)
Affinity DataIC50:  13.4nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340532((S)-1-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzy...)
Affinity DataIC50:  13.7nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340545((S)-5-(2-((2,4-difluorophenoxy)methyl)pyrrolidin-1...)
Affinity DataIC50:  15.2nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340546((S)-5-(2-((2,4-difluorophenoxy)methyl)azetidin-1-y...)
Affinity DataIC50:  15.3nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340544((S)-5-(2-((2,4-difluorophenoxy)methyl)azetidin-1-y...)
Affinity DataIC50:  15.4nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340529((S)-1-(4-(2-fluoroethoxy)benzyl)-5-(2-((pyridin-3-...)
Affinity DataIC50:  17.6nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340532((S)-1-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzy...)
Affinity DataIC50:  17.6nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340541((S)-1-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)me...)
Affinity DataIC50:  18nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340538((S)-2-(1-(4-(2-fluoroethoxy)benzyl)-2-oxo-5-(2-(ph...)
Affinity DataIC50:  18.3nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340528((S)-1-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzy...)
Affinity DataIC50:  19.2nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340534((S)-2-(1-(4-(2-fluoroethoxy)benzyl)-2-oxo-5-(2-(ph...)
Affinity DataIC50:  22.4nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340539((S)-2-(1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-2-ox...)
Affinity DataIC50:  23.3nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340535((S)-2-(1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-2-ox...)
Affinity DataIC50:  24.4nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340526((S)-1-(4-(2-fluoroethoxy)benzyl)-5-(2-(phenoxymeth...)
Affinity DataIC50:  26.1nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340540((S)-2-(1-(4-(2-fluoroethoxy)benzyl)-2-oxo-5-(2-((p...)
Affinity DataIC50:  26.5nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340528((S)-1-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzy...)
Affinity DataIC50:  26.9nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340527((S)-1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-5-(2-(p...)
Affinity DataIC50:  27.9nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340527((S)-1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-5-(2-(p...)
Affinity DataIC50:  28.9nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340536((S)-2-(1-(4-(2-fluoroethoxy)benzyl)-2-oxo-5-(2-((p...)
Affinity DataIC50:  45nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340537((S)-2-(1-(4-methoxybenzyl)-2-oxo-5-(2-((pyridin-3-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340535((S)-2-(1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-2-ox...)
Affinity DataIC50:  68.3nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340539((S)-2-(1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-2-ox...)
Affinity DataIC50:  70nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340538((S)-2-(1-(4-(2-fluoroethoxy)benzyl)-2-oxo-5-(2-(ph...)
Affinity DataIC50:  96.3nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 147 total ) | Next | Last >>
Jump to: