Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50001153
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013228(6-Methoxy-4-methyl-1-o-tolyl-2,3-dihydro-1H-pyrrol...)
Affinity DataKi:  290nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50001247(8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic ac...)
Affinity DataKi:  290nMAssay Description:Binding affinity of compound towards H+/K+ ATPase for activation was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50008977((8-Benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-yl)-...)
Affinity DataIC50:  101nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013237(3-Methyl-4-(4-methyl-2,3-dihydro-pyrrolo[3,2-c]qui...)
Affinity DataIC50:  170nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013243(4-Methyl-1-o-tolyl-2,3-dihydro-1H-pyrrolo[3,2-c]qu...)
Affinity DataIC50:  410nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013240(4,6-Dimethyl-1-o-tolyl-2,3-dihydro-1H-pyrrolo[3,2-...)
Affinity DataIC50:  420nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013236(1-(4-Methoxy-2-methyl-phenyl)-4-methyl-2,3-dihydro...)
Affinity DataIC50:  530nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50000672(6-Methoxy-4-methyl-1-o-tolyl-1H-pyrrolo[3,2-c]quin...)
Affinity DataIC50:  640nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013228(6-Methoxy-4-methyl-1-o-tolyl-2,3-dihydro-1H-pyrrol...)
Affinity DataIC50:  660nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013231(6-Fluoro-4-methyl-1-o-tolyl-2,3-dihydro-1H-pyrrolo...)
Affinity DataIC50:  750nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50001247(8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic ac...)
Affinity DataIC50:  850nMpH: 7.0Assay Description:Binding affinity of compound towards H+/K+ ATPase for activation was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013230(6-Methoxy-1-(4-methoxy-2-methyl-phenyl)-4-methyl-2...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013233(4-Methyl-1-o-tolyl-2,3-dihydro-1H-pyrrolo[3,2-c]qu...)
Affinity DataIC50:  1.10E+3nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013229(6-Methoxy-4,5-dimethyl-1-o-tolyl-2,3-dihydro-1H-py...)
Affinity DataIC50:  1.30E+3nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013239(1-(2,6-Dimethyl-phenyl)-4-methyl-2,3-dihydro-1H-py...)
Affinity DataIC50:  1.50E+3nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013234(6-Methoxy-1-(2-methoxy-phenyl)-4-methyl-2,3-dihydr...)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013226(6-Methoxy-4-methyl-1-phenyl-2,3-dihydro-1H-pyrrolo...)
Affinity DataIC50:  2.40E+3nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013242(4-Methyl-1-o-tolyl-2,3-dihydro-1H-pyrrolo[3,2-c]qu...)
Affinity DataIC50:  2.90E+3nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013227(7-Methoxy-1-o-tolyl-1,2,3,4-tetrahydro-benzo[h][1,...)
Affinity DataIC50:  3.10E+3nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013235(1-o-Tolyl-1H-imidazo[4,5-c]quinoline | CHEMBL35727...)
Affinity DataIC50:  9.80E+3nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013225(1-Benzyl-6-methoxy-4-methyl-2,3-dihydro-1H-pyrrolo...)
Affinity DataIC50:  1.10E+4nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013238(1-o-Tolyl-1,3-dihydro-imidazo[4,5-c]quinoline-2-th...)
Affinity DataIC50:  2.20E+4nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1(Sus scrofa (Pig))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013241(1-o-Tolyl-1H-[1,2,3]triazolo[4,5-c]quinoline | CHE...)
Affinity DataIC50:  6.90E+4nMAssay Description:In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed