Compile Data Set for Download or QSAR
maximum 50k data
Found 55 Enz. Inhib. hit(s) with all data for entry = 50033701
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50140317((R)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349898(CHEMBL1814707)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50140317((R)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349898(CHEMBL1814707)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349902(CHEMBL1814711)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50330853(CHEMBL66552 | Sodium; 2-[4-(2-oxo-cyclopentylmethy...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349918(CHEMBL1814726)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349902(CHEMBL1814711)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50330851(CHEMBL1275921 | fluoro loxoprofen)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349920(CHEMBL1814728)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349919(CHEMBL1814727)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349901(CHEMBL1814710)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50330851(CHEMBL1275921 | fluoro loxoprofen)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50330853(CHEMBL66552 | Sodium; 2-[4-(2-oxo-cyclopentylmethy...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50330850(CHEMBL1275940 | bromoloxoprofen)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349907(CHEMBL1814716)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349915(CHEMBL1814724)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349920(CHEMBL1814728)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349900(CHEMBL1814709)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349901(CHEMBL1814710)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349903(CHEMBL1814712)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349904(CHEMBL1814713)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50330850(CHEMBL1275940 | bromoloxoprofen)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349911(CHEMBL1814720)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349908(CHEMBL1814717)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349913(CHEMBL1814722)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349917(CHEMBL1814725)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349900(CHEMBL1814709)
Affinity DataIC50:  9.30E+4nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349914(CHEMBL1814723)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349907(CHEMBL1814716)
Affinity DataIC50:  1.74E+5nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349915(CHEMBL1814724)
Affinity DataIC50:  1.74E+5nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349899(CHEMBL1814708)
Affinity DataIC50:  2.70E+5nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349903(CHEMBL1814712)
Affinity DataIC50:  2.90E+5nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349911(CHEMBL1814720)
Affinity DataIC50:  3.10E+5nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349918(CHEMBL1814726)
Affinity DataIC50:  3.26E+5nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349904(CHEMBL1814713)
Affinity DataIC50:  4.20E+5nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349913(CHEMBL1814722)
Affinity DataIC50:  4.30E+5nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349908(CHEMBL1814717)
Affinity DataIC50:  4.60E+5nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349912(CHEMBL1814721)
Affinity DataIC50:  4.70E+5nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349916(CHEMBL1814706)
Affinity DataIC50:  5.15E+5nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349899(CHEMBL1814708)
Affinity DataIC50:  5.40E+5nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349912(CHEMBL1814721)
Affinity DataIC50:  5.40E+5nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349914(CHEMBL1814723)
Affinity DataIC50:  5.75E+5nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349919(CHEMBL1814727)
Affinity DataIC50:  6.50E+5nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349906(CHEMBL1814715)
Affinity DataIC50:  7.58E+5nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349905(CHEMBL1814714)
Affinity DataIC50:  8.00E+5nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349909(CHEMBL1814718)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50349917(CHEMBL1814725)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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