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PubMed code 21665470

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50348088
PNG
(CHEMBL78920)
Show SMILES OC(=O)[C@H]1NCC=C1
Show InChI InChI=1S/C5H7NO2/c7-5(8)4-2-1-3-6-4/h1-2,4,6H,3H2,(H,7,8)/t4-/m0/s1
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 8.50E+3n/an/an/an/an/an/a



Korea Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged PHD2 assessed as inhibition of hydroxylation of fluorescein-labeled HIF1alpha CODD peptide after 1 hr by fluorescent polariz...


Bioorg Med Chem Lett 21: 4325-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.05.050
BindingDB Entry DOI: 10.7270/Q2T43TDW
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50348089
PNG
(CHEMBL1800368)
Show SMILES OC(=O)[C@@H]1CC(=S)CN1
Show InChI InChI=1S/C5H7NO2S/c7-5(8)4-1-3(9)2-6-4/h4,6H,1-2H2,(H,7,8)/t4-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

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DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.97E+4n/an/an/an/an/an/a



Korea Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged PHD2 assessed as inhibition of hydroxylation of fluorescein-labeled HIF1alpha CODD peptide after 1 hr by fluorescent polariz...


Bioorg Med Chem Lett 21: 4325-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.05.050
BindingDB Entry DOI: 10.7270/Q2T43TDW
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%