Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with all data for entry = 50033926
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50168789(3-[1-(4-Chloro-benzyl)-3-methyl-1H-indol-2-yl]-2,2...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of microsomal PGESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50168789(3-[1-(4-Chloro-benzyl)-3-methyl-1H-indol-2-yl]-2,2...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human recombinant microsomal PGES-1 expressed in freestyle 293-f cells assessed as conversion of PGH2 to PGE2 after 15 mins by enzyme i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50353950(CHEMBL1828850)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human recombinant microsomal PGES-1 expressed in freestyle 293-f cells assessed as conversion of PGH2 to PGE2 after 15 mins by enzyme i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50353951(CHEMBL1828851)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human recombinant microsomal PGES-1 expressed in freestyle 293-f cells assessed as conversion of PGH2 to PGE2 after 15 mins by enzyme i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of microsomal PGESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50012899((Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of microsomal PGESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed