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Found 4 Enz. Inhib. hit(s) with all data for entry = 50034215
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
State Key Laboratory Of Bioactive Substance And Function Of Natural Medicines, And Key Laboratory Of Bioactive Substances And Resources Utilization Of Chinese Herbal Medicine

Curated by ChEMBL
LigandPNGBDBM50358967(CHEMBL1923782)
Affinity DataIC50:  2.81E+3nMAssay Description:Inhibition of GST-tagged human recombinant PTP1B assessed as dephosphorylation of para-nitrophenyl phosphate after 10 mins by spectrophotometric anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
State Key Laboratory Of Bioactive Substance And Function Of Natural Medicines, And Key Laboratory Of Bioactive Substances And Resources Utilization Of Chinese Herbal Medicine

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  3.84E+3nMAssay Description:Inhibition of GST-tagged human recombinant PTP1B assessed as dephosphorylation of para-nitrophenyl phosphate after 10 mins by spectrophotometric anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
State Key Laboratory Of Bioactive Substance And Function Of Natural Medicines, And Key Laboratory Of Bioactive Substances And Resources Utilization Of Chinese Herbal Medicine

Curated by ChEMBL
LigandPNGBDBM50358968(CHEMBL1923783)
Affinity DataIC50:  4.26E+3nMAssay Description:Inhibition of GST-tagged human recombinant PTP1B assessed as dephosphorylation of para-nitrophenyl phosphate after 10 mins by spectrophotometric anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
State Key Laboratory Of Bioactive Substance And Function Of Natural Medicines, And Key Laboratory Of Bioactive Substances And Resources Utilization Of Chinese Herbal Medicine

Curated by ChEMBL
LigandPNGBDBM50358966(CHEMBL1923781)
Affinity DataIC50:  8.63E+3nMAssay Description:Inhibition of GST-tagged human recombinant PTP1B assessed as dephosphorylation of para-nitrophenyl phosphate after 10 mins by spectrophotometric anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed