Compile Data Set for Download or QSAR
maximum 50k data
Found 107 Enz. Inhib. hit(s) with all data for entry = 50034328
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360603(CHEMBL1933536)
Affinity DataIC50:  14nMAssay Description:Inhibition of CYP2D6 using dextromethorphan as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360610(CHEMBL1933552)
Affinity DataIC50:  189nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50:  246nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360605(CHEMBL1933538)
Affinity DataIC50:  476nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360603(CHEMBL1933536)
Affinity DataIC50:  495nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360616(CHEMBL1933545)
Affinity DataIC50:  501nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360620(CHEMBL1933549)
Affinity DataIC50:  560nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50:  598nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50:  655nMAssay Description:Inhibition of CYP2D6 using dextromethorphan as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360615(CHEMBL1933544)
Affinity DataIC50:  811nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360617(CHEMBL1933546)
Affinity DataIC50:  843nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360610(CHEMBL1933552)
Affinity DataIC50:  970nMAssay Description:Inhibition of MerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360602(CHEMBL1933535)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360619(CHEMBL1933548)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360610(CHEMBL1933552)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of CK1deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360606(CHEMBL1933539)
Affinity DataIC50:  1.81E+3nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360618(CHEMBL1933547)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50:  2.34E+3nMAssay Description:Inhibition of MerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of MerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360607(CHEMBL1933540)
Affinity DataIC50:  2.88E+3nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360608(CHEMBL1933072)
Affinity DataIC50:  4.41E+3nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360612(CHEMBL1933541)
Affinity DataIC50:  4.93E+3nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50:  5.25E+3nMAssay Description:Inhibition of AxlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50:  6.61E+3nMAssay Description:Inhibition of CK1deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360605(CHEMBL1933538)
Affinity DataIC50:  6.93E+3nMAssay Description:Inhibition of MerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360604(CHEMBL1933537)
Affinity DataIC50:  8.66E+3nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of CK1deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibition of AxlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360605(CHEMBL1933538)
Affinity DataIC50:  1.94E+4nMAssay Description:Inhibition of AxlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360610(CHEMBL1933552)
Affinity DataIC50:  2.19E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360610(CHEMBL1933552)
Affinity DataIC50:  2.27E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360610(CHEMBL1933552)
Affinity DataIC50:  2.38E+4nMAssay Description:Inhibition of AxlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360613(CHEMBL1933542)
Affinity DataIC50:  2.79E+4nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360605(CHEMBL1933538)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360610(CHEMBL1933552)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of INSRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360610(CHEMBL1933552)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360609(CHEMBL1933551)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360605(CHEMBL1933538)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360605(CHEMBL1933538)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PKCzetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360605(CHEMBL1933538)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Cdk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360605(CHEMBL1933538)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360605(CHEMBL1933538)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Gsk3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360605(CHEMBL1933538)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360605(CHEMBL1933538)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IKKiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360605(CHEMBL1933538)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360605(CHEMBL1933538)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MAPKAP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360605(CHEMBL1933538)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Pak4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50360605(CHEMBL1933538)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360605(CHEMBL1933538)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Pim-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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