Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50034372
TargetBeta-secretase 1(Homo sapiens (Human))
Sissa-Isas

Curated by ChEMBL
LigandPNGBDBM16034(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)
Affinity DataIC50:  10nMAssay Description:Inhibition of BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated 1 hr before substrate addit...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Sissa-Isas

Curated by ChEMBL
LigandPNGBDBM50361334(CHEMBL1933457)
Affinity DataIC50:  5.59E+3nMAssay Description:Inhibition of BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated 1 hr before substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Sissa-Isas

Curated by ChEMBL
LigandPNGBDBM50361333(CHEMBL1933459)
Affinity DataIC50:  5.95E+3nMAssay Description:Inhibition of BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated 1 hr before substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Sissa-Isas

Curated by ChEMBL
LigandPNGBDBM50361335(CHEMBL1933456)
Affinity DataIC50:  7.32E+3nMAssay Description:Inhibition of BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated 1 hr before substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Sissa-Isas

Curated by ChEMBL
LigandPNGBDBM50361336(CHEMBL1933455)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated 1 hr before substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed