Compile Data Set for Download or QSAR
maximum 50k data
Found 49 Enz. Inhib. hit(s) with all data for entry = 50042110
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399293(CHEMBL2086582)
Affinity DataKi:  660nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in GH4C1 cells after 1 hr by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420604(CHEMBL2087443)
Affinity DataIC50:  3.25E+3nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420606(CHEMBL2087447)
Affinity DataIC50:  3.90E+3nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420607(CHEMBL2087448)
Affinity DataIC50:  5.80E+3nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420605(CHEMBL2087445)
Affinity DataIC50:  6.40E+3nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420608(CHEMBL2087453)
Affinity DataIC50:  1.16E+4nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399293(CHEMBL2086582)
Affinity DataIC50:  2.42E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by IonWorks assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420607(CHEMBL2087448)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420610(CHEMBL2087457)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399293(CHEMBL2086582)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420611(CHEMBL2086584)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420606(CHEMBL2087447)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420605(CHEMBL2087445)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420604(CHEMBL2087443)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420611(CHEMBL2086584)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399293(CHEMBL2086582)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420610(CHEMBL2087457)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420609(CHEMBL2087456)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420608(CHEMBL2087453)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420609(CHEMBL2087456)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420612(CHEMBL2087437)
Affinity DataEC50:  1.22E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399293(CHEMBL2086582)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at human alpha7 nAChR expressed in CHO cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420614(CHEMBL2087438)
Affinity DataEC50:  2.13E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420615(CHEMBL2087440)
Affinity DataEC50:  2.33E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420604(CHEMBL2087443)
Affinity DataEC50:  430nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420616(CHEMBL2087444)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420605(CHEMBL2087445)
Affinity DataEC50:  1.45E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420606(CHEMBL2087447)
Affinity DataEC50:  1.52E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420607(CHEMBL2087448)
Affinity DataEC50:  1.15E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420617(CHEMBL2087449)
Affinity DataEC50:  6.22E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420618(CHEMBL2087450)
Affinity DataEC50:  3.07E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420619(CHEMBL2087451)
Affinity DataEC50:  4.18E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420620(CHEMBL2087452)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420608(CHEMBL2087453)
Affinity DataEC50:  590nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420621(CHEMBL2087454)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420622(CHEMBL2087455)
Affinity DataEC50:  2.22E+4nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420609(CHEMBL2087456)
Affinity DataEC50:  1.05E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420610(CHEMBL2087457)
Affinity DataEC50:  670nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420623(CHEMBL2087458)
Affinity DataEC50:  5.41E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420624(CHEMBL2087459)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399293(CHEMBL2086582)
Affinity DataEC50:  180nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420625(CHEMBL2086583)
Affinity DataEC50:  6.83E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420611(CHEMBL2086584)
Affinity DataEC50:  360nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420626(CHEMBL2086585)
Affinity DataEC50:  3.47E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM91595(PHA568487)
Affinity DataEC50:  36.2nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acet...)
Affinity DataEC50:  3.12E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420627(CHEMBL2087446)
Affinity DataEC50:  3.16E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399293(CHEMBL2086582)
Affinity DataEC50:  4.40E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420613(CHEMBL2086404)
Affinity DataEC50:  780nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in GH4C1 cells assessed as calcium influx measured every 1 sec for 1 min followed by every 30 secs for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed