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PubMed code 22512907

Compile data set for download or QSAR
Found 49 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381600
PNG
(CHEMBL2018254)
Show SMILES COc1ccc(cc1)N1C(=S)O\C(=C/c2cc(F)c(O)c(Cl)c2)C1=O
Show InChI InChI=1S/C17H11ClFNO4S/c1-23-11-4-2-10(3-5-11)20-16(22)14(24-17(20)25)8-9-6-12(18)15(21)13(19)7-9/h2-8,21H,1H3/b14-8-
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n/an/a 1n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381570
PNG
(CHEMBL2018139)
Show SMILES Oc1ccc(\C=C2/OC(=S)N(C2=O)c2ccc(F)cc2)cc1Br
Show InChI InChI=1S/C16H9BrFNO3S/c17-12-7-9(1-6-13(12)20)8-14-15(21)19(16(23)22-14)11-4-2-10(18)3-5-11/h1-8,20H/b14-8-
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n/an/a 2n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381572
PNG
(CHEMBL2018141)
Show SMILES Cc1ccc(cc1)N1C(=S)O\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C17H12BrNO3S/c1-10-2-5-12(6-3-10)19-16(21)15(22-17(19)23)9-11-4-7-14(20)13(18)8-11/h2-9,20H,1H3/b15-9-
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n/an/a 2n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381596
PNG
(CHEMBL2018249)
Show SMILES COc1ccc(cc1)N1C(=S)O\C(=C/c2ccc(O)c(F)c2)C1=O
Show InChI InChI=1S/C17H12FNO4S/c1-22-12-5-3-11(4-6-12)19-16(21)15(23-17(19)24)9-10-2-7-14(20)13(18)8-10/h2-9,20H,1H3/b15-9-
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n/an/a 2n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381564
PNG
(CHEMBL2018131)
Show SMILES Oc1ccc(\C=C2/SC(=S)N(C3CCCCC3)C2=O)cc1Br
Show InChI InChI=1S/C16H16BrNO2S2/c17-12-8-10(6-7-13(12)19)9-14-15(20)18(16(21)22-14)11-4-2-1-3-5-11/h6-9,11,19H,1-5H2/b14-9-
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n/an/a 3n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381573
PNG
(CHEMBL2018142)
Show SMILES Oc1ccc(\C=C2/OC(=S)N(C2=O)c2ccc(cc2)C(F)(F)F)cc1Br
Show InChI InChI=1S/C17H9BrF3NO3S/c18-12-7-9(1-6-13(12)23)8-14-15(24)22(16(26)25-14)11-4-2-10(3-5-11)17(19,20)21/h1-8,23H/b14-8-
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n/an/a 3n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381586
PNG
(CHEMBL2018238)
Show SMILES COc1ccc(cn1)N1C(=O)O\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C16H11BrN2O5/c1-23-14-5-3-10(8-18-14)19-15(21)13(24-16(19)22)7-9-2-4-12(20)11(17)6-9/h2-8,20H,1H3/b13-7-
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n/an/a 4n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381590
PNG
(CHEMBL2018242)
Show SMILES CN(C)c1ccc(cn1)N1C(=O)O\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C17H14BrN3O4/c1-20(2)15-6-4-11(9-19-15)21-16(23)14(25-17(21)24)8-10-3-5-13(22)12(18)7-10/h3-9,22H,1-2H3/b14-8-
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n/an/a 4n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381597
PNG
(CHEMBL2018250)
Show SMILES COc1ccc(cc1)N1C(=S)O\C(=C/c2ccc(O)c(Cl)c2)C1=O
Show InChI InChI=1S/C17H12ClNO4S/c1-22-12-5-3-11(4-6-12)19-16(21)15(23-17(19)24)9-10-2-7-14(20)13(18)8-10/h2-9,20H,1H3/b15-9-
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n/an/a 4n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381559
PNG
(CHEMBL2018253)
Show SMILES COc1ccc(cc1)N1C(=S)O\C(=C/c2cc(F)c(O)c(F)c2)C1=O
Show InChI InChI=1S/C17H11F2NO4S/c1-23-11-4-2-10(3-5-11)20-16(22)14(24-17(20)25)8-9-6-12(18)15(21)13(19)7-9/h2-8,21H,1H3/b14-8-
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n/an/a 5n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381598
PNG
(CHEMBL2018251)
Show SMILES COc1ccc(cc1)N1C(=S)O\C(=C/c2ccc(O)cc2Cl)C1=O
Show InChI InChI=1S/C17H12ClNO4S/c1-22-13-6-3-11(4-7-13)19-16(21)15(23-17(19)24)8-10-2-5-12(20)9-14(10)18/h2-9,20H,1H3/b15-8-
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n/an/a 5n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381566
PNG
(CHEMBL2018135)
Show SMILES Oc1ccc(\C=C2/OC(=S)N(C2=O)c2ccccc2)cc1Br
Show InChI InChI=1S/C16H10BrNO3S/c17-12-8-10(6-7-13(12)19)9-14-15(20)18(16(22)21-14)11-4-2-1-3-5-11/h1-9,19H/b14-9-
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n/an/a 6n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381571
PNG
(CHEMBL2018140)
Show SMILES Oc1ccc(\C=C2/OC(=S)N(C2=O)c2ccc(Cl)cc2)cc1Br
Show InChI InChI=1S/C16H9BrClNO3S/c17-12-7-9(1-6-13(12)20)8-14-15(21)19(16(23)22-14)11-4-2-10(18)3-5-11/h1-8,20H/b14-8-
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n/an/a 6n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381567
PNG
(CHEMBL2018136)
Show SMILES COc1cccc(c1)N1C(=S)O\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C17H12BrNO4S/c1-22-12-4-2-3-11(9-12)19-16(21)15(23-17(19)24)8-10-5-6-14(20)13(18)7-10/h2-9,20H,1H3/b15-8-
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n/an/a 7n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381599
PNG
(CHEMBL2018252)
Show SMILES COc1ccc(cc1)N1C(=S)O\C(=C/c2cc(Cl)c(O)c(Cl)c2)C1=O
Show InChI InChI=1S/C17H11Cl2NO4S/c1-23-11-4-2-10(3-5-11)20-16(22)14(24-17(20)25)8-9-6-12(18)15(21)13(19)7-9/h2-8,21H,1H3/b14-8-
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n/an/a 12n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381569
PNG
(CHEMBL2018138)
Show SMILES Oc1ccc(\C=C2/OC(=S)N(C2=O)c2ccc3OCOc3c2)cc1Br
Show InChI InChI=1S/C17H10BrNO5S/c18-11-5-9(1-3-12(11)20)6-15-16(21)19(17(25)24-15)10-2-4-13-14(7-10)23-8-22-13/h1-7,20H,8H2/b15-6-
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n/an/a 12n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50360766
PNG
(CHEMBL1934492)
Show SMILES COc1ccc(cc1)N1C(=S)O\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C17H12BrNO4S/c1-22-12-5-3-11(4-6-12)19-16(21)15(23-17(19)24)9-10-2-7-14(20)13(18)8-10/h2-9,20H,1H3/b15-9-
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n/an/a 13n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50360767
PNG
(CHEMBL1934493)
Show SMILES COc1ccc(cc1)N1C(=S)S\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C17H12BrNO3S2/c1-22-12-5-3-11(4-6-12)19-16(21)15(24-17(19)23)9-10-2-7-14(20)13(18)8-10/h2-9,20H,1H3/b15-9-
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n/an/a 14n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381574
PNG
(CHEMBL2018223)
Show SMILES Oc1ccc(\C=C2/OC(=S)N(C2=O)c2ccc(cc2)C#N)cc1Br
Show InChI InChI=1S/C17H9BrN2O3S/c18-13-7-11(3-6-14(13)21)8-15-16(22)20(17(24)23-15)12-4-1-10(9-19)2-5-12/h1-8,21H/b15-8-
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n/an/a 19n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381594
PNG
(CHEMBL2018247)
Show SMILES COc1ccc(cc1)N1C(=S)O\C(=C/c2ccc(O)c(C)c2)C1=O
Show InChI InChI=1S/C18H15NO4S/c1-11-9-12(3-8-15(11)20)10-16-17(21)19(18(24)23-16)13-4-6-14(22-2)7-5-13/h3-10,20H,1-2H3/b16-10-
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n/an/a 20n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381589
PNG
(CHEMBL2018241)
Show SMILES Oc1ccc(\C=C2/OC(=O)N(C2=O)c2ccc(Cl)nc2)cc1Br
Show InChI InChI=1S/C15H8BrClN2O4/c16-10-5-8(1-3-11(10)20)6-12-14(21)19(15(22)23-12)9-2-4-13(17)18-7-9/h1-7,20H/b12-6-
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n/an/a 20n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381558
PNG
(CHEMBL2018232)
Show SMILES Oc1ccc(\C=C2/OC(=O)N(C2=O)c2ccc(NC(=O)C3CCCCC3)cc2)cc1Br
Show InChI InChI=1S/C23H21BrN2O5/c24-18-12-14(6-11-19(18)27)13-20-22(29)26(23(30)31-20)17-9-7-16(8-10-17)25-21(28)15-4-2-1-3-5-15/h6-13,15,27H,1-5H2,(H,25,28)/b20-13-
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n/an/a 21n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381588
PNG
(CHEMBL2018240)
Show SMILES Oc1ccc(\C=C2/OC(=O)N(C2=O)c2ccc(F)nc2)cc1Br
Show InChI InChI=1S/C15H8BrFN2O4/c16-10-5-8(1-3-11(10)20)6-12-14(21)19(15(22)23-12)9-2-4-13(17)18-7-9/h1-7,20H/b12-6-
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n/an/a 21n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381585
PNG
(CHEMBL2018237)
Show SMILES Oc1ccc(\C=C2/OC(=O)N(C2=O)c2cccnc2)cc1Br
Show InChI InChI=1S/C15H9BrN2O4/c16-11-6-9(3-4-12(11)19)7-13-14(20)18(15(21)22-13)10-2-1-5-17-8-10/h1-8,19H/b13-7-
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n/an/a 22n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50360765
PNG
(CHEMBL1934491)
Show SMILES COc1ccc(cc1)N1C(=O)O\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C17H12BrNO5/c1-23-12-5-3-11(4-6-12)19-16(21)15(24-17(19)22)9-10-2-7-14(20)13(18)8-10/h2-9,20H,1H3/b15-9-
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n/an/a 23n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381575
PNG
(CHEMBL2018225)
Show SMILES COC(=O)c1ccc(cc1)N1C(=O)O\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C18H12BrNO6/c1-25-17(23)11-3-5-12(6-4-11)20-16(22)15(26-18(20)24)9-10-2-7-14(21)13(19)8-10/h2-9,21H,1H3/b15-9-
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n/an/a 24n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381580
PNG
(CHEMBL2018230)
Show SMILES CN(C)c1ccc(cc1)N1C(=O)O\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C18H15BrN2O4/c1-20(2)12-4-6-13(7-5-12)21-17(23)16(25-18(21)24)10-11-3-8-15(22)14(19)9-11/h3-10,22H,1-2H3/b16-10-
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n/an/a 25n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381602
PNG
(CHEMBL2018260)
Show SMILES COc1ccc(cc1)N1C(=S)O\C(=C/c2ccc(O)c(Br)n2)C1=O
Show InChI InChI=1S/C16H11BrN2O4S/c1-22-11-5-3-10(4-6-11)19-15(21)13(23-16(19)24)8-9-2-7-12(20)14(17)18-9/h2-8,20H,1H3/b13-8-
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n/an/a 42n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381578
PNG
(CHEMBL2018228)
Show SMILES Oc1ccc(\C=C2/OC(=O)N(C2=O)c2ccc(cc2)C(=O)N2CCNCC2)cc1Br
Show InChI InChI=1S/C21H18BrN3O5/c22-16-11-13(1-6-17(16)26)12-18-20(28)25(21(29)30-18)15-4-2-14(3-5-15)19(27)24-9-7-23-8-10-24/h1-6,11-12,23,26H,7-10H2/b18-12-
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n/an/a 42n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381576
PNG
(CHEMBL2018226)
Show SMILES CNC(=O)c1ccc(cc1)N1C(=O)O\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C18H13BrN2O5/c1-20-16(23)11-3-5-12(6-4-11)21-17(24)15(26-18(21)25)9-10-2-7-14(22)13(19)8-10/h2-9,22H,1H3,(H,20,23)/b15-9-
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n/an/a 56n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381581
PNG
(CHEMBL2018231)
Show SMILES CC(=O)Nc1ccc(cc1)N1C(=O)O\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C18H13BrN2O5/c1-10(22)20-12-3-5-13(6-4-12)21-17(24)16(26-18(21)25)9-11-2-7-15(23)14(19)8-11/h2-9,23H,1H3,(H,20,22)/b16-9-
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n/an/a 57n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381568
PNG
(CHEMBL2018137)
Show SMILES COc1ccccc1N1C(=S)O\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C17H12BrNO4S/c1-22-14-5-3-2-4-12(14)19-16(21)15(23-17(19)24)9-10-6-7-13(20)11(18)8-10/h2-9,20H,1H3/b15-9-
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n/an/a 60n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381577
PNG
(CHEMBL2018227)
Show SMILES CN(C)C(=O)c1ccc(cc1)N1C(=O)O\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C19H15BrN2O5/c1-21(2)17(24)12-4-6-13(7-5-12)22-18(25)16(27-19(22)26)10-11-3-8-15(23)14(20)9-11/h3-10,23H,1-2H3/b16-10-
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n/an/a 65n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381587
PNG
(CHEMBL2018239)
Show SMILES Cc1ccc(cn1)N1C(=O)O\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C16H11BrN2O4/c1-9-2-4-11(8-18-9)19-15(21)14(23-16(19)22)7-10-3-5-13(20)12(17)6-10/h2-8,20H,1H3/b14-7-
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n/an/a 67n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381584
PNG
(CHEMBL2018236)
Show SMILES Oc1ccc(\C=C2/OC(=O)N(C2=O)c2ccccn2)cc1Br
Show InChI InChI=1S/C15H9BrN2O4/c16-10-7-9(4-5-11(10)19)8-12-14(20)18(15(21)22-12)13-3-1-2-6-17-13/h1-8,19H/b12-8-
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n/an/a 74n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381565
PNG
(CHEMBL2018132)
Show SMILES Oc1ccc(\C=C2/SC(=S)N(C3CCOCC3)C2=O)cc1Br
Show InChI InChI=1S/C15H14BrNO3S2/c16-11-7-9(1-2-12(11)18)8-13-14(19)17(15(21)22-13)10-3-5-20-6-4-10/h1-2,7-8,10,18H,3-6H2/b13-8-
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n/an/a 75n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381557
PNG
(CHEMBL2018134)
Show SMILES COc1ccc(CN2C(=S)S\C(=C/c3ccc(O)c(Br)c3)C2=O)cc1
Show InChI InChI=1S/C18H14BrNO3S2/c1-23-13-5-2-11(3-6-13)10-20-17(22)16(25-18(20)24)9-12-4-7-15(21)14(19)8-12/h2-9,21H,10H2,1H3/b16-9-
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n/an/a 90n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381582
PNG
(CHEMBL2018233)
Show SMILES CSc1ccc(cc1)N1C(=O)O\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C17H12BrNO4S/c1-24-12-5-3-11(4-6-12)19-16(21)15(23-17(19)22)9-10-2-7-14(20)13(18)8-10/h2-9,20H,1H3/b15-9-
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n/an/a 90n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381601
PNG
(CHEMBL2018259)
Show SMILES COc1ccc(cc1)N1C(=S)O\C(=C/c2ccc(O)cn2)C1=O
Show InChI InChI=1S/C16H12N2O4S/c1-21-13-6-3-11(4-7-13)18-15(20)14(22-16(18)23)8-10-2-5-12(19)9-17-10/h2-9,19H,1H3/b14-8-
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n/an/a 90n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381592
PNG
(CHEMBL2018245)
Show SMILES COc1ccc(cc1)N1C(=S)SC(Cc2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C17H14BrNO3S2/c1-22-12-5-3-11(4-6-12)19-16(21)15(24-17(19)23)9-10-2-7-14(20)13(18)8-10/h2-8,15,20H,9H2,1H3
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n/an/a 90n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381591
PNG
(CHEMBL2018243)
Show SMILES COc1ccc(cc1)N1C(=S)S\C(=C(/C)c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C18H14BrNO3S2/c1-10(11-3-8-15(21)14(19)9-11)16-17(22)20(18(24)25-16)12-4-6-13(23-2)7-5-12/h3-9,21H,1-2H3/b16-10+
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n/an/a 90n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381561
PNG
(CHEMBL2018128)
Show SMILES Oc1ccc(\C=C2/SC(=S)N(CC=C)C2=O)cc1Br
Show InChI InChI=1S/C13H10BrNO2S2/c1-2-5-15-12(17)11(19-13(15)18)7-8-3-4-10(16)9(14)6-8/h2-4,6-7,16H,1,5H2/b11-7-
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n/an/a 120n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381593
PNG
(CHEMBL2018246)
Show SMILES COc1ccc(cc1)N1C(=S)O\C(=C/c2ccc(O)cc2)C1=O
Show InChI InChI=1S/C17H13NO4S/c1-21-14-8-4-12(5-9-14)18-16(20)15(22-17(18)23)10-11-2-6-13(19)7-3-11/h2-10,19H,1H3/b15-10-
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n/an/a 121n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381563
PNG
(CHEMBL2018130)
Show SMILES COCCN1C(=S)S\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C13H12BrNO3S2/c1-18-5-4-15-12(17)11(20-13(15)19)7-8-2-3-10(16)9(14)6-8/h2-3,6-7,16H,4-5H2,1H3/b11-7-
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n/an/a 190n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381595
PNG
(CHEMBL2018248)
Show SMILES COc1ccc(cc1)N1C(=S)O\C(=C/c2ccc(O)c(OC)c2)C1=O
Show InChI InChI=1S/C18H15NO5S/c1-22-13-6-4-12(5-7-13)19-17(21)16(24-18(19)25)10-11-3-8-14(20)15(9-11)23-2/h3-10,20H,1-2H3/b16-10-
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n/an/a 270n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381579
PNG
(CHEMBL2018229)
Show SMILES Oc1ccc(\C=C2/OC(=O)N(C2=O)c2ccc(cc2)C(=O)N2CCOCC2)cc1Br
Show InChI InChI=1S/C21H17BrN2O6/c22-16-11-13(1-6-17(16)25)12-18-20(27)24(21(28)30-18)15-4-2-14(3-5-15)19(26)23-7-9-29-10-8-23/h1-6,11-12,25H,7-10H2/b18-12-
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n/an/a 300n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381562
PNG
(CHEMBL2018129)
Show SMILES Oc1ccc(\C=C2/SC(=S)N(CC#C)C2=O)cc1Br
Show InChI InChI=1S/C13H8BrNO2S2/c1-2-5-15-12(17)11(19-13(15)18)7-8-3-4-10(16)9(14)6-8/h1,3-4,6-7,16H,5H2/b11-7-
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n/an/a 300n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381560
PNG
(CHEMBL2018127)
Show SMILES CN1C(=S)S\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C11H8BrNO2S2/c1-13-10(15)9(17-11(13)16)5-6-2-3-8(14)7(12)4-6/h2-5,14H,1H3/b9-5-
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n/an/a 890n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 3


(Homo sapiens (Human))
BDBM50381583
PNG
(CHEMBL2018234)
Show SMILES CS(=O)(=O)c1ccc(cc1)N1C(=O)O\C(=C/c2ccc(O)c(Br)c2)C1=O
Show InChI InChI=1S/C17H12BrNO6S/c1-26(23,24)12-5-3-11(4-6-12)19-16(21)15(25-17(19)22)9-10-2-7-14(20)13(18)8-10/h2-9,20H,1H3/b15-9-
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n/an/a 900n/an/an/an/an/an/a



Sumitomo Chemical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant 17-beta-HSD3 expressed in human HeLa cells using androstenedione as substrate preincubated for 30 mins prior substrat...


Bioorg Med Chem 20: 3242-54 (2012)


Article DOI: 10.1016/j.bmc.2012.03.052
BindingDB Entry DOI: 10.7270/Q2RF5W2G
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%