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PubMed code 22520153

Compile data set for download or QSAR
Found 135 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50151982
PNG
(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)
Show SMILES NC(=O)c1cc2cc(ccc2o1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1
Show InChI InChI=1S/C26H27N5O2/c27-16-18-4-6-23-22(13-18)19(17-29-23)3-1-2-8-30-9-11-31(12-10-30)21-5-7-24-20(14-21)15-25(33-24)26(28)32/h4-7,13-15,17,29H,1-3,8-12H2,(H2,28,32)
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0.300n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50151982
PNG
(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)
Show SMILES NC(=O)c1cc2cc(ccc2o1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1
Show InChI InChI=1S/C26H27N5O2/c27-16-18-4-6-23-22(13-18)19(17-29-23)3-1-2-8-30-9-11-31(12-10-30)21-5-7-24-20(14-21)15-25(33-24)26(28)32/h4-7,13-15,17,29H,1-3,8-12H2,(H2,28,32)
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0.5n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50384954
PNG
(CHEMBL2037521)
Show SMILES C(CCc1nc2ccccc2s1)CN1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C19H23N5S/c1-2-7-17-16(6-1)22-18(25-17)8-3-4-11-23-12-14-24(15-13-23)19-20-9-5-10-21-19/h1-2,5-7,9-10H,3-4,8,11-15H2
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0.800n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM30130
PNG
(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)
Show SMILES CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1
Show InChI InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3
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1.10n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384967
PNG
(CHEMBL2037531)
Show SMILES O=C(CCCCN1CCC(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C23H26N2OS/c26-21(23-24-20-10-4-5-12-22(20)27-23)11-6-7-15-25-16-13-19(14-17-25)18-8-2-1-3-9-18/h1-5,8-10,12,19H,6-7,11,13-17H2
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3.40n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384966
PNG
(CHEMBL2037530)
Show SMILES O=C(CCCCN1CCN(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C22H25N3OS/c26-20(22-23-19-10-4-5-12-21(19)27-22)11-6-7-13-24-14-16-25(17-15-24)18-8-2-1-3-9-18/h1-5,8-10,12H,6-7,11,13-17H2
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3.60n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384965
PNG
(CHEMBL2037529)
Show SMILES O=C(CCCCN1CCN(CC1)c1ncccn1)c1nc2ccccc2s1
Show InChI InChI=1S/C20H23N5OS/c26-17(19-23-16-6-1-2-8-18(16)27-19)7-3-4-11-24-12-14-25(15-13-24)20-21-9-5-10-22-20/h1-2,5-6,8-10H,3-4,7,11-15H2
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3.60n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50384969
PNG
(CHEMBL2037431)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H24ClN3S/c22-17-8-10-18(11-9-17)25-15-13-24(14-16-25)12-4-3-7-21-23-19-5-1-2-6-20(19)26-21/h1-2,5-6,8-11H,3-4,7,12-16H2
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4n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384955
PNG
(CHEMBL2037522)
Show SMILES C(CCc1nc2ccccc2s1)CN1CCc2ccccc2C1
Show InChI InChI=1S/C20H22N2S/c1-2-8-17-15-22(14-12-16(17)7-1)13-6-5-11-20-21-18-9-3-4-10-19(18)23-20/h1-4,7-10H,5-6,11-15H2
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5.10n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50363900
PNG
(CHEMBL1946258)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H24ClN3OS/c23-17-8-10-18(11-9-17)26-14-4-13-25(15-16-26)12-3-6-20(27)22-24-19-5-1-2-7-21(19)28-22/h1-2,5,7-11H,3-4,6,12-16H2
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5.30n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384954
PNG
(CHEMBL2037521)
Show SMILES C(CCc1nc2ccccc2s1)CN1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C19H23N5S/c1-2-7-17-16(6-1)22-18(25-17)8-3-4-11-23-12-14-24(15-13-23)19-20-9-5-10-21-19/h1-2,5-7,9-10H,3-4,8,11-15H2
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6.60n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384967
PNG
(CHEMBL2037531)
Show SMILES O=C(CCCCN1CCC(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C23H26N2OS/c26-21(23-24-20-10-4-5-12-22(20)27-23)11-6-7-15-25-16-13-19(14-17-25)18-8-2-1-3-9-18/h1-5,8-10,12,19H,6-7,11,13-17H2
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7.30n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384962
PNG
(CHEMBL2037526)
Show SMILES O=C(CCCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C25H28N4O2S/c30-21(23-27-20-10-4-5-12-22(20)32-23)11-6-7-15-28-16-13-25(14-17-28)24(31)26-18-29(25)19-8-2-1-3-9-19/h1-5,8-10,12H,6-7,11,13-18H2,(H,26,31)
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25n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384954
PNG
(CHEMBL2037521)
Show SMILES C(CCc1nc2ccccc2s1)CN1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C19H23N5S/c1-2-7-17-16(6-1)22-18(25-17)8-3-4-11-23-12-14-24(15-13-23)19-20-9-5-10-21-19/h1-2,5-7,9-10H,3-4,8,11-15H2
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26.5n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384964
PNG
(CHEMBL2037528)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H24ClN3OS/c23-17-8-10-18(11-9-17)26-15-13-25(14-16-26)12-4-3-6-20(27)22-24-19-5-1-2-7-21(19)28-22/h1-2,5,7-11H,3-4,6,12-16H2
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28.3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50363897
PNG
(CHEMBL1946254)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H26ClN3S/c23-18-9-11-19(12-10-18)26-15-5-14-25(16-17-26)13-4-3-8-22-24-20-6-1-2-7-21(20)27-22/h1-2,6-7,9-12H,3-5,8,13-17H2
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28.6n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384955
PNG
(CHEMBL2037522)
Show SMILES C(CCc1nc2ccccc2s1)CN1CCc2ccccc2C1
Show InChI InChI=1S/C20H22N2S/c1-2-8-17-15-22(14-12-16(17)7-1)13-6-5-11-20-21-18-9-3-4-10-19(18)23-20/h1-4,7-10H,5-6,11-15H2
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30.8n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50384968
PNG
(CHEMBL2037430)
Show SMILES Clc1ccc(cc1)N1CCN(CCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C20H22ClN3S/c21-16-7-9-17(10-8-16)24-14-12-23(13-15-24)11-3-6-20-22-18-4-1-2-5-19(18)25-20/h1-2,4-5,7-10H,3,6,11-15H2
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31n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50363898
PNG
(CHEMBL1946255)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H24ClN3S/c22-17-8-10-18(11-9-17)25-14-4-13-24(15-16-25)12-3-7-21-23-19-5-1-2-6-20(19)26-21/h1-2,5-6,8-11H,3-4,7,12-16H2
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34n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50384955
PNG
(CHEMBL2037522)
Show SMILES C(CCc1nc2ccccc2s1)CN1CCc2ccccc2C1
Show InChI InChI=1S/C20H22N2S/c1-2-8-17-15-22(14-12-16(17)7-1)13-6-5-11-20-21-18-9-3-4-10-19(18)23-20/h1-4,7-10H,5-6,11-15H2
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35.6n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384968
PNG
(CHEMBL2037430)
Show SMILES Clc1ccc(cc1)N1CCN(CCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C20H22ClN3S/c21-16-7-9-17(10-8-16)24-14-12-23(13-15-24)11-3-6-20-22-18-4-1-2-5-19(18)25-20/h1-2,4-5,7-10H,3,6,11-15H2
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36n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50384959
PNG
(CHEMBL2037518)
Show SMILES O=C(CCCN1CCC(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C22H24N2OS/c25-20(22-23-19-9-4-5-11-21(19)26-22)10-6-14-24-15-12-18(13-16-24)17-7-2-1-3-8-17/h1-5,7-9,11,18H,6,10,12-16H2
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44.4n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Homo sapiens (human))
BDBM50384964
PNG
(CHEMBL2037528)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H24ClN3OS/c23-17-8-10-18(11-9-17)26-15-13-25(14-16-26)12-4-3-6-20(27)22-24-19-5-1-2-7-21(19)28-22/h1-2,5,7-11H,3-4,6,12-16H2
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46n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Pyrilamine from human H1 histamine receptor by liquid scintillation assay


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent noradrenaline transporter


(Homo sapiens (human))
BDBM50384967
PNG
(CHEMBL2037531)
Show SMILES O=C(CCCCN1CCC(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C23H26N2OS/c26-21(23-24-20-10-4-5-12-22(20)27-23)11-6-7-15-25-16-13-19(14-17-25)18-8-2-1-3-9-18/h1-5,8-10,12,19H,6-7,11,13-17H2
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49n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Nisoxetine from human NET by liquid scintillation assay


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50384960
PNG
(CHEMBL2037519)
Show SMILES O=C(CCCN1CCN(CC1)c1ncccn1)c1nc2ccccc2s1
Show InChI InChI=1S/C19H21N5OS/c25-16(18-22-15-5-1-2-7-17(15)26-18)6-3-10-23-11-13-24(14-12-23)19-20-8-4-9-21-19/h1-2,4-5,7-9H,3,6,10-14H2
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51.5n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Homo sapiens (human))
BDBM50384967
PNG
(CHEMBL2037531)
Show SMILES O=C(CCCCN1CCC(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C23H26N2OS/c26-21(23-24-20-10-4-5-12-22(20)27-23)11-6-7-15-25-16-13-19(14-17-25)18-8-2-1-3-9-18/h1-5,8-10,12,19H,6-7,11,13-17H2
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52n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Pyrilamine from human H1 histamine receptor by liquid scintillation assay


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50384966
PNG
(CHEMBL2037530)
Show SMILES O=C(CCCCN1CCN(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C22H25N3OS/c26-20(22-23-19-10-4-5-12-21(19)27-22)11-6-7-13-24-14-16-25(17-15-24)18-8-2-1-3-9-18/h1-5,8-10,12H,6-7,11,13-17H2
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62.6n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384960
PNG
(CHEMBL2037519)
Show SMILES O=C(CCCN1CCN(CC1)c1ncccn1)c1nc2ccccc2s1
Show InChI InChI=1S/C19H21N5OS/c25-16(18-22-15-5-1-2-7-17(15)26-18)6-3-10-23-11-13-24(14-12-23)19-20-8-4-9-21-19/h1-2,4-5,7-9H,3,6,10-14H2
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63n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50384967
PNG
(CHEMBL2037531)
Show SMILES O=C(CCCCN1CCC(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C23H26N2OS/c26-21(23-24-20-10-4-5-12-22(20)27-23)11-6-7-15-25-16-13-19(14-17-25)18-8-2-1-3-9-18/h1-5,8-10,12,19H,6-7,11,13-17H2
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64n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50363899
PNG
(CHEMBL1946257)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C23H26ClN3OS/c24-18-9-11-19(12-10-18)27-15-5-14-26(16-17-27)13-4-3-7-21(28)23-25-20-6-1-2-8-22(20)29-23/h1-2,6,8-12H,3-5,7,13-17H2
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65n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50363897
PNG
(CHEMBL1946254)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H26ClN3S/c23-18-9-11-19(12-10-18)26-15-5-14-25(16-17-26)13-4-3-8-22-24-20-6-1-2-7-21(20)27-22/h1-2,6-7,9-12H,3-5,8,13-17H2
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65n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50384955
PNG
(CHEMBL2037522)
Show SMILES C(CCc1nc2ccccc2s1)CN1CCc2ccccc2C1
Show InChI InChI=1S/C20H22N2S/c1-2-8-17-15-22(14-12-16(17)7-1)13-6-5-11-20-21-18-9-3-4-10-19(18)23-20/h1-4,7-10H,5-6,11-15H2
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65.5n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 2C (5-HT2C)


(Homo sapiens (human))
BDBM30130
PNG
(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)
Show SMILES CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1
Show InChI InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3
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72n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Binding affinity to human 5HT2C receptor by radioligand displacement assay


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50384964
PNG
(CHEMBL2037528)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H24ClN3OS/c23-17-8-10-18(11-9-17)26-15-13-25(14-16-26)12-4-3-6-20(27)22-24-19-5-1-2-7-21(19)28-22/h1-2,5,7-11H,3-4,6,12-16H2
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81n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384959
PNG
(CHEMBL2037518)
Show SMILES O=C(CCCN1CCC(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C22H24N2OS/c25-20(22-23-19-9-4-5-11-21(19)26-22)10-6-14-24-15-12-18(13-16-24)17-7-2-1-3-8-17/h1-5,7-9,11,18H,6,10,12-16H2
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85n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384969
PNG
(CHEMBL2037431)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H24ClN3S/c22-17-8-10-18(11-9-17)25-15-13-24(14-16-25)12-4-3-7-21-23-19-5-1-2-6-20(19)26-21/h1-2,5-6,8-11H,3-4,7,12-16H2
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90.5n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50384964
PNG
(CHEMBL2037528)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H24ClN3OS/c23-17-8-10-18(11-9-17)26-15-13-25(14-16-26)12-4-3-6-20(27)22-24-19-5-1-2-7-21(19)28-22/h1-2,5,7-11H,3-4,6,12-16H2
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100n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384962
PNG
(CHEMBL2037526)
Show SMILES O=C(CCCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C25H28N4O2S/c30-21(23-27-20-10-4-5-12-22(20)32-23)11-6-7-15-28-16-13-25(14-17-28)24(31)26-18-29(25)19-8-2-1-3-9-19/h1-5,8-10,12H,6-7,11,13-18H2,(H,26,31)
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103n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50384966
PNG
(CHEMBL2037530)
Show SMILES O=C(CCCCN1CCN(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C22H25N3OS/c26-20(22-23-19-10-4-5-12-21(19)27-22)11-6-7-13-24-14-16-25(17-15-24)18-8-2-1-3-9-18/h1-5,8-10,12H,6-7,11,13-17H2
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105n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50384967
PNG
(CHEMBL2037531)
Show SMILES O=C(CCCCN1CCC(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C23H26N2OS/c26-21(23-24-20-10-4-5-12-22(20)27-23)11-6-7-15-25-16-13-19(14-17-25)18-8-2-1-3-9-18/h1-5,8-10,12,19H,6-7,11,13-17H2
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107n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384956
PNG
(CHEMBL2037523)
Show SMILES C(CCc1nc2ccccc2s1)CN1Cc2ccccc2C1
Show InChI InChI=1S/C19H20N2S/c1-2-8-16-14-21(13-15(16)7-1)12-6-5-11-19-20-17-9-3-4-10-18(17)22-19/h1-4,7-10H,5-6,11-14H2
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111n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50363900
PNG
(CHEMBL1946258)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H24ClN3OS/c23-17-8-10-18(11-9-17)26-14-4-13-25(15-16-26)12-3-6-20(27)22-24-19-5-1-2-7-21(19)28-22/h1-2,5,7-11H,3-4,6,12-16H2
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126n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50384961
PNG
(CHEMBL2037520)
Show SMILES Clc1ccc2n(C3CCN(CCCCC(=O)c4nc5ccccc5s4)CC3)c(=O)[nH]c2c1
Show InChI InChI=1S/C24H25ClN4O2S/c25-16-8-9-20-19(15-16)27-24(31)29(20)17-10-13-28(14-11-17)12-4-3-6-21(30)23-26-18-5-1-2-7-22(18)32-23/h1-2,5,7-9,15,17H,3-4,6,10-14H2,(H,27,31)
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127n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384969
PNG
(CHEMBL2037431)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H24ClN3S/c22-17-8-10-18(11-9-17)25-15-13-24(14-16-25)12-4-3-7-21-23-19-5-1-2-6-20(19)26-21/h1-2,5-6,8-11H,3-4,7,12-16H2
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132n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50384970
PNG
(CHEMBL2037432)
Show SMILES OC1(CCN(CCCCc2nc3ccccc3s2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H25ClN2OS/c23-18-10-8-17(9-11-18)22(26)12-15-25(16-13-22)14-4-3-7-21-24-19-5-1-2-6-20(19)27-21/h1-2,5-6,8-11,26H,3-4,7,12-16H2
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140n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50384956
PNG
(CHEMBL2037523)
Show SMILES C(CCc1nc2ccccc2s1)CN1Cc2ccccc2C1
Show InChI InChI=1S/C19H20N2S/c1-2-8-16-14-21(13-15(16)7-1)12-6-5-11-19-20-17-9-3-4-10-18(17)22-19/h1-4,7-10H,5-6,11-14H2
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141n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50363897
PNG
(CHEMBL1946254)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H26ClN3S/c23-18-9-11-19(12-10-18)26-15-5-14-25(16-17-26)13-4-3-8-22-24-20-6-1-2-7-21(20)27-22/h1-2,6-7,9-12H,3-5,8,13-17H2
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159n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50384962
PNG
(CHEMBL2037526)
Show SMILES O=C(CCCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C25H28N4O2S/c30-21(23-27-20-10-4-5-12-22(20)32-23)11-6-7-15-28-16-13-25(14-17-28)24(31)26-18-29(25)19-8-2-1-3-9-19/h1-5,8-10,12H,6-7,11,13-18H2,(H,26,31)
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162n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50384969
PNG
(CHEMBL2037431)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H24ClN3S/c22-17-8-10-18(11-9-17)25-15-13-24(14-16-25)12-4-3-7-21-23-19-5-1-2-6-20(19)26-21/h1-2,5-6,8-11H,3-4,7,12-16H2
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166n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50384967
PNG
(CHEMBL2037531)
Show SMILES O=C(CCCCN1CCC(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C23H26N2OS/c26-21(23-24-20-10-4-5-12-22(20)27-23)11-6-7-15-25-16-13-19(14-17-25)18-8-2-1-3-9-18/h1-5,8-10,12,19H,6-7,11,13-17H2
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180n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50384956
PNG
(CHEMBL2037523)
Show SMILES C(CCc1nc2ccccc2s1)CN1Cc2ccccc2C1
Show InChI InChI=1S/C19H20N2S/c1-2-8-16-14-21(13-15(16)7-1)12-6-5-11-19-20-17-9-3-4-10-18(17)22-19/h1-4,7-10H,5-6,11-14H2
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186n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384966
PNG
(CHEMBL2037530)
Show SMILES O=C(CCCCN1CCN(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C22H25N3OS/c26-20(22-23-19-10-4-5-12-21(19)27-22)11-6-7-13-24-14-16-25(17-15-24)18-8-2-1-3-9-18/h1-5,8-10,12H,6-7,11,13-17H2
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198n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384970
PNG
(CHEMBL2037432)
Show SMILES OC1(CCN(CCCCc2nc3ccccc3s2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H25ClN2OS/c23-18-10-8-17(9-11-18)22(26)12-15-25(16-13-22)14-4-3-7-21-24-19-5-1-2-6-20(19)27-21/h1-2,5-6,8-11,26H,3-4,7,12-16H2
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201n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384966
PNG
(CHEMBL2037530)
Show SMILES O=C(CCCCN1CCN(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C22H25N3OS/c26-20(22-23-19-10-4-5-12-21(19)27-22)11-6-7-13-24-14-16-25(17-15-24)18-8-2-1-3-9-18/h1-5,8-10,12H,6-7,11,13-17H2
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204n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50384956
PNG
(CHEMBL2037523)
Show SMILES C(CCc1nc2ccccc2s1)CN1Cc2ccccc2C1
Show InChI InChI=1S/C19H20N2S/c1-2-8-16-14-21(13-15(16)7-1)12-6-5-11-19-20-17-9-3-4-10-18(17)22-19/h1-4,7-10H,5-6,11-14H2
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211n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384963
PNG
(CHEMBL2037527)
Show SMILES O=C(CCCCN1Cc2ccccc2C1)c1nc2ccccc2s1
Show InChI InChI=1S/C20H20N2OS/c23-18(20-21-17-9-3-4-11-19(17)24-20)10-5-6-12-22-13-15-7-1-2-8-16(15)14-22/h1-4,7-9,11H,5-6,10,12-14H2
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214n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50363898
PNG
(CHEMBL1946255)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H24ClN3S/c22-17-8-10-18(11-9-17)25-14-4-13-24(15-16-25)12-3-7-21-23-19-5-1-2-6-20(19)26-21/h1-2,5-6,8-11H,3-4,7,12-16H2
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216n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384961
PNG
(CHEMBL2037520)
Show SMILES Clc1ccc2n(C3CCN(CCCCC(=O)c4nc5ccccc5s4)CC3)c(=O)[nH]c2c1
Show InChI InChI=1S/C24H25ClN4O2S/c25-16-8-9-20-19(15-16)27-24(31)29(20)17-10-13-28(14-11-17)12-4-3-6-21(30)23-26-18-5-1-2-7-22(18)32-23/h1-2,5,7-9,15,17H,3-4,6,10-14H2,(H,27,31)
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217n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384969
PNG
(CHEMBL2037431)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H24ClN3S/c22-17-8-10-18(11-9-17)25-15-13-24(14-16-25)12-4-3-7-21-23-19-5-1-2-6-20(19)26-21/h1-2,5-6,8-11H,3-4,7,12-16H2
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219n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384954
PNG
(CHEMBL2037521)
Show SMILES C(CCc1nc2ccccc2s1)CN1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C19H23N5S/c1-2-7-17-16(6-1)22-18(25-17)8-3-4-11-23-12-14-24(15-13-23)19-20-9-5-10-21-19/h1-2,5-7,9-10H,3-4,8,11-15H2
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224n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50384954
PNG
(CHEMBL2037521)
Show SMILES C(CCc1nc2ccccc2s1)CN1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C19H23N5S/c1-2-7-17-16(6-1)22-18(25-17)8-3-4-11-23-12-14-24(15-13-23)19-20-9-5-10-21-19/h1-2,5-7,9-10H,3-4,8,11-15H2
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229n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50384963
PNG
(CHEMBL2037527)
Show SMILES O=C(CCCCN1Cc2ccccc2C1)c1nc2ccccc2s1
Show InChI InChI=1S/C20H20N2OS/c23-18(20-21-17-9-3-4-11-19(17)24-20)10-5-6-12-22-13-15-7-1-2-8-16(15)14-22/h1-4,7-9,11H,5-6,10,12-14H2
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237n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50384963
PNG
(CHEMBL2037527)
Show SMILES O=C(CCCCN1Cc2ccccc2C1)c1nc2ccccc2s1
Show InChI InChI=1S/C20H20N2OS/c23-18(20-21-17-9-3-4-11-19(17)24-20)10-5-6-12-22-13-15-7-1-2-8-16(15)14-22/h1-4,7-9,11H,5-6,10,12-14H2
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242n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384961
PNG
(CHEMBL2037520)
Show SMILES Clc1ccc2n(C3CCN(CCCCC(=O)c4nc5ccccc5s4)CC3)c(=O)[nH]c2c1
Show InChI InChI=1S/C24H25ClN4O2S/c25-16-8-9-20-19(15-16)27-24(31)29(20)17-10-13-28(14-11-17)12-4-3-6-21(30)23-26-18-5-1-2-7-22(18)32-23/h1-2,5,7-9,15,17H,3-4,6,10-14H2,(H,27,31)
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252n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50363897
PNG
(CHEMBL1946254)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H26ClN3S/c23-18-9-11-19(12-10-18)26-15-5-14-25(16-17-26)13-4-3-8-22-24-20-6-1-2-7-21(20)27-22/h1-2,6-7,9-12H,3-5,8,13-17H2
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259n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50363897
PNG
(CHEMBL1946254)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H26ClN3S/c23-18-9-11-19(12-10-18)26-15-5-14-25(16-17-26)13-4-3-8-22-24-20-6-1-2-7-21(20)27-22/h1-2,6-7,9-12H,3-5,8,13-17H2
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263n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50384962
PNG
(CHEMBL2037526)
Show SMILES O=C(CCCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C25H28N4O2S/c30-21(23-27-20-10-4-5-12-22(20)32-23)11-6-7-15-28-16-13-25(14-17-28)24(31)26-18-29(25)19-8-2-1-3-9-19/h1-5,8-10,12H,6-7,11,13-18H2,(H,26,31)
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284n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384959
PNG
(CHEMBL2037518)
Show SMILES O=C(CCCN1CCC(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C22H24N2OS/c25-20(22-23-19-9-4-5-11-21(19)26-22)10-6-14-24-15-12-18(13-16-24)17-7-2-1-3-8-17/h1-5,7-9,11,18H,6,10,12-16H2
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287n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50384966
PNG
(CHEMBL2037530)
Show SMILES O=C(CCCCN1CCN(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C22H25N3OS/c26-20(22-23-19-10-4-5-12-21(19)27-22)11-6-7-13-24-14-16-25(17-15-24)18-8-2-1-3-9-18/h1-5,8-10,12H,6-7,11,13-17H2
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298n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384968
PNG
(CHEMBL2037430)
Show SMILES Clc1ccc(cc1)N1CCN(CCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C20H22ClN3S/c21-16-7-9-17(10-8-16)24-14-12-23(13-15-24)11-3-6-20-22-18-4-1-2-5-19(18)25-20/h1-2,4-5,7-10H,3,6,11-15H2
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312n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50384969
PNG
(CHEMBL2037431)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H24ClN3S/c22-17-8-10-18(11-9-17)25-15-13-24(14-16-25)12-4-3-7-21-23-19-5-1-2-6-20(19)26-21/h1-2,5-6,8-11H,3-4,7,12-16H2
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329n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50384965
PNG
(CHEMBL2037529)
Show SMILES O=C(CCCCN1CCN(CC1)c1ncccn1)c1nc2ccccc2s1
Show InChI InChI=1S/C20H23N5OS/c26-17(19-23-16-6-1-2-8-18(16)27-19)7-3-4-11-24-12-14-25(15-13-24)20-21-9-5-10-22-20/h1-2,5-6,8-10H,3-4,7,11-15H2
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337n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50384957
PNG
(CHEMBL2037524)
Show SMILES Clc1ccc(cc1)N1CCN(CCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H22ClN3OS/c22-16-7-9-17(10-8-16)25-14-12-24(13-15-25)11-3-5-19(26)21-23-18-4-1-2-6-20(18)27-21/h1-2,4,6-10H,3,5,11-15H2
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342n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50384965
PNG
(CHEMBL2037529)
Show SMILES O=C(CCCCN1CCN(CC1)c1ncccn1)c1nc2ccccc2s1
Show InChI InChI=1S/C20H23N5OS/c26-17(19-23-16-6-1-2-8-18(16)27-19)7-3-4-11-24-12-14-25(15-13-24)20-21-9-5-10-22-20/h1-2,5-6,8-10H,3-4,7,11-15H2
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346n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384958
PNG
(CHEMBL2037525)
Show SMILES O=C(CCCN1CCN(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C21H23N3OS/c25-19(21-22-18-9-4-5-11-20(18)26-21)10-6-12-23-13-15-24(16-14-23)17-7-2-1-3-8-17/h1-5,7-9,11H,6,10,12-16H2
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350n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50363900
PNG
(CHEMBL1946258)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H24ClN3OS/c23-17-8-10-18(11-9-17)26-14-4-13-25(15-16-26)12-3-6-20(27)22-24-19-5-1-2-7-21(19)28-22/h1-2,5,7-11H,3-4,6,12-16H2
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356n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50363897
PNG
(CHEMBL1946254)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H26ClN3S/c23-18-9-11-19(12-10-18)26-15-5-14-25(16-17-26)13-4-3-8-22-24-20-6-1-2-7-21(20)27-22/h1-2,6-7,9-12H,3-5,8,13-17H2
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413n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50384959
PNG
(CHEMBL2037518)
Show SMILES O=C(CCCN1CCC(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C22H24N2OS/c25-20(22-23-19-9-4-5-11-21(19)26-22)10-6-14-24-15-12-18(13-16-24)17-7-2-1-3-8-17/h1-5,7-9,11,18H,6,10,12-16H2
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426n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50363898
PNG
(CHEMBL1946255)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H24ClN3S/c22-17-8-10-18(11-9-17)25-14-4-13-24(15-16-25)12-3-7-21-23-19-5-1-2-6-20(19)26-21/h1-2,5-6,8-11H,3-4,7,12-16H2
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431n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50384957
PNG
(CHEMBL2037524)
Show SMILES Clc1ccc(cc1)N1CCN(CCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H22ClN3OS/c22-16-7-9-17(10-8-16)25-14-12-24(13-15-25)11-3-5-19(26)21-23-18-4-1-2-6-20(18)27-21/h1-2,4,6-10H,3,5,11-15H2
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491n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50363899
PNG
(CHEMBL1946257)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C23H26ClN3OS/c24-18-9-11-19(12-10-18)27-15-5-14-26(16-17-27)13-4-3-7-21(28)23-25-20-6-1-2-8-22(20)29-23/h1-2,6,8-12H,3-5,7,13-17H2
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495n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384965
PNG
(CHEMBL2037529)
Show SMILES O=C(CCCCN1CCN(CC1)c1ncccn1)c1nc2ccccc2s1
Show InChI InChI=1S/C20H23N5OS/c26-17(19-23-16-6-1-2-8-18(16)27-19)7-3-4-11-24-12-14-25(15-13-24)20-21-9-5-10-22-20/h1-2,5-6,8-10H,3-4,7,11-15H2
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505n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50384963
PNG
(CHEMBL2037527)
Show SMILES O=C(CCCCN1Cc2ccccc2C1)c1nc2ccccc2s1
Show InChI InChI=1S/C20H20N2OS/c23-18(20-21-17-9-3-4-11-19(17)24-20)10-5-6-12-22-13-15-7-1-2-8-16(15)14-22/h1-4,7-9,11H,5-6,10,12-14H2
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512n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50384962
PNG
(CHEMBL2037526)
Show SMILES O=C(CCCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C25H28N4O2S/c30-21(23-27-20-10-4-5-12-22(20)32-23)11-6-7-15-28-16-13-25(14-17-28)24(31)26-18-29(25)19-8-2-1-3-9-19/h1-5,8-10,12H,6-7,11,13-18H2,(H,26,31)
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518n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384964
PNG
(CHEMBL2037528)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H24ClN3OS/c23-17-8-10-18(11-9-17)26-15-13-25(14-16-26)12-4-3-6-20(27)22-24-19-5-1-2-7-21(19)28-22/h1-2,5,7-11H,3-4,6,12-16H2
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523n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384959
PNG
(CHEMBL2037518)
Show SMILES O=C(CCCN1CCC(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C22H24N2OS/c25-20(22-23-19-9-4-5-11-21(19)26-22)10-6-14-24-15-12-18(13-16-24)17-7-2-1-3-8-17/h1-5,7-9,11,18H,6,10,12-16H2
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530n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50384961
PNG
(CHEMBL2037520)
Show SMILES Clc1ccc2n(C3CCN(CCCCC(=O)c4nc5ccccc5s4)CC3)c(=O)[nH]c2c1
Show InChI InChI=1S/C24H25ClN4O2S/c25-16-8-9-20-19(15-16)27-24(31)29(20)17-10-13-28(14-11-17)12-4-3-6-21(30)23-26-18-5-1-2-7-22(18)32-23/h1-2,5,7-9,15,17H,3-4,6,10-14H2,(H,27,31)
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565n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384967
PNG
(CHEMBL2037531)
Show SMILES O=C(CCCCN1CCC(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C23H26N2OS/c26-21(23-24-20-10-4-5-12-22(20)27-23)11-6-7-15-25-16-13-19(14-17-25)18-8-2-1-3-9-18/h1-5,8-10,12,19H,6-7,11,13-17H2
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642n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50151982
PNG
(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)
Show SMILES NC(=O)c1cc2cc(ccc2o1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1
Show InChI InChI=1S/C26H27N5O2/c27-16-18-4-6-23-22(13-18)19(17-29-23)3-1-2-8-30-9-11-31(12-10-30)21-5-7-24-20(14-21)15-25(33-24)26(28)32/h4-7,13-15,17,29H,1-3,8-12H2,(H2,28,32)
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666n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50363898
PNG
(CHEMBL1946255)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H24ClN3S/c22-17-8-10-18(11-9-17)25-14-4-13-24(15-16-25)12-3-7-21-23-19-5-1-2-6-20(19)26-21/h1-2,5-6,8-11H,3-4,7,12-16H2
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696n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50384959
PNG
(CHEMBL2037518)
Show SMILES O=C(CCCN1CCC(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C22H24N2OS/c25-20(22-23-19-9-4-5-11-21(19)26-22)10-6-14-24-15-12-18(13-16-24)17-7-2-1-3-8-17/h1-5,7-9,11,18H,6,10,12-16H2
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706n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384970
PNG
(CHEMBL2037432)
Show SMILES OC1(CCN(CCCCc2nc3ccccc3s2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H25ClN2OS/c23-18-10-8-17(9-11-18)22(26)12-15-25(16-13-22)14-4-3-7-21-24-19-5-1-2-6-20(19)27-21/h1-2,5-6,8-11,26H,3-4,7,12-16H2
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771n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50384968
PNG
(CHEMBL2037430)
Show SMILES Clc1ccc(cc1)N1CCN(CCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C20H22ClN3S/c21-16-7-9-17(10-8-16)24-14-12-23(13-15-24)11-3-6-20-22-18-4-1-2-5-19(18)25-20/h1-2,4-5,7-10H,3,6,11-15H2
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790n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50384970
PNG
(CHEMBL2037432)
Show SMILES OC1(CCN(CCCCc2nc3ccccc3s2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H25ClN2OS/c23-18-10-8-17(9-11-18)22(26)12-15-25(16-13-22)14-4-3-7-21-24-19-5-1-2-6-20(19)27-21/h1-2,5-6,8-11,26H,3-4,7,12-16H2
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922n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50384970
PNG
(CHEMBL2037432)
Show SMILES OC1(CCN(CCCCc2nc3ccccc3s2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H25ClN2OS/c23-18-10-8-17(9-11-18)22(26)12-15-25(16-13-22)14-4-3-7-21-24-19-5-1-2-6-20(19)27-21/h1-2,5-6,8-11,26H,3-4,7,12-16H2
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983n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384956
PNG
(CHEMBL2037523)
Show SMILES C(CCc1nc2ccccc2s1)CN1Cc2ccccc2C1
Show InChI InChI=1S/C19H20N2S/c1-2-8-16-14-21(13-15(16)7-1)12-6-5-11-19-20-17-9-3-4-10-18(17)22-19/h1-4,7-10H,5-6,11-14H2
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990n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50363899
PNG
(CHEMBL1946257)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C23H26ClN3OS/c24-18-9-11-19(12-10-18)27-15-5-14-26(16-17-27)13-4-3-7-21(28)23-25-20-6-1-2-8-22(20)29-23/h1-2,6,8-12H,3-5,7,13-17H2
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1.00E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50363900
PNG
(CHEMBL1946258)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H24ClN3OS/c23-17-8-10-18(11-9-17)26-14-4-13-25(15-16-26)12-3-6-20(27)22-24-19-5-1-2-7-21(19)28-22/h1-2,5,7-11H,3-4,6,12-16H2
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1.04E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50384968
PNG
(CHEMBL2037430)
Show SMILES Clc1ccc(cc1)N1CCN(CCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C20H22ClN3S/c21-16-7-9-17(10-8-16)24-14-12-23(13-15-24)11-3-6-20-22-18-4-1-2-5-19(18)25-20/h1-2,4-5,7-10H,3,6,11-15H2
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1.18E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50363899
PNG
(CHEMBL1946257)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C23H26ClN3OS/c24-18-9-11-19(12-10-18)27-15-5-14-26(16-17-27)13-4-3-7-21(28)23-25-20-6-1-2-8-22(20)29-23/h1-2,6,8-12H,3-5,7,13-17H2
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1.22E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50384955
PNG
(CHEMBL2037522)
Show SMILES C(CCc1nc2ccccc2s1)CN1CCc2ccccc2C1
Show InChI InChI=1S/C20H22N2S/c1-2-8-17-15-22(14-12-16(17)7-1)13-6-5-11-20-21-18-9-3-4-10-19(18)23-20/h1-4,7-10H,5-6,11-15H2
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1.33E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 2C (5-HT2C)


(Homo sapiens (human))
BDBM50363897
PNG
(CHEMBL1946254)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H26ClN3S/c23-18-9-11-19(12-10-18)26-15-5-14-25(16-17-26)13-4-3-8-22-24-20-6-1-2-7-21(20)27-22/h1-2,6-7,9-12H,3-5,8,13-17H2
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1.42E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Binding affinity to human 5HT2C receptor by radioligand displacement assay


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384960
PNG
(CHEMBL2037519)
Show SMILES O=C(CCCN1CCN(CC1)c1ncccn1)c1nc2ccccc2s1
Show InChI InChI=1S/C19H21N5OS/c25-16(18-22-15-5-1-2-7-17(15)26-18)6-3-10-23-11-13-24(14-12-23)19-20-8-4-9-21-19/h1-2,4-5,7-9H,3,6,10-14H2
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1.52E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384961
PNG
(CHEMBL2037520)
Show SMILES Clc1ccc2n(C3CCN(CCCCC(=O)c4nc5ccccc5s4)CC3)c(=O)[nH]c2c1
Show InChI InChI=1S/C24H25ClN4O2S/c25-16-8-9-20-19(15-16)27-24(31)29(20)17-10-13-28(14-11-17)12-4-3-6-21(30)23-26-18-5-1-2-7-22(18)32-23/h1-2,5,7-9,15,17H,3-4,6,10-14H2,(H,27,31)
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1.56E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Dopamine receptor


(RAT)
BDBM50384961
PNG
(CHEMBL2037520)
Show SMILES Clc1ccc2n(C3CCN(CCCCC(=O)c4nc5ccccc5s4)CC3)c(=O)[nH]c2c1
Show InChI InChI=1S/C24H25ClN4O2S/c25-16-8-9-20-19(15-16)27-24(31)29(20)17-10-13-28(14-11-17)12-4-3-6-21(30)23-26-18-5-1-2-7-22(18)32-23/h1-2,5,7-9,15,17H,3-4,6,10-14H2,(H,27,31)
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1.71E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50363899
PNG
(CHEMBL1946257)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C23H26ClN3OS/c24-18-9-11-19(12-10-18)27-15-5-14-26(16-17-27)13-4-3-7-21(28)23-25-20-6-1-2-8-22(20)29-23/h1-2,6,8-12H,3-5,7,13-17H2
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1.98E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384957
PNG
(CHEMBL2037524)
Show SMILES Clc1ccc(cc1)N1CCN(CCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H22ClN3OS/c22-16-7-9-17(10-8-16)25-14-12-24(13-15-25)11-3-5-19(26)21-23-18-4-1-2-6-20(18)27-21/h1-2,4,6-10H,3,5,11-15H2
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2.00E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50363898
PNG
(CHEMBL1946255)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H24ClN3S/c22-17-8-10-18(11-9-17)25-14-4-13-24(15-16-25)12-3-7-21-23-19-5-1-2-6-20(19)26-21/h1-2,5-6,8-11H,3-4,7,12-16H2
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2.06E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 2C (5-HT2C)


(Homo sapiens (human))
BDBM50384966
PNG
(CHEMBL2037530)
Show SMILES O=C(CCCCN1CCN(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C22H25N3OS/c26-20(22-23-19-10-4-5-12-21(19)27-22)11-6-7-13-24-14-16-25(17-15-24)18-8-2-1-3-9-18/h1-5,8-10,12H,6-7,11,13-17H2
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2.14E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Binding affinity to human 5HT2C receptor by radioligand displacement assay


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384960
PNG
(CHEMBL2037519)
Show SMILES O=C(CCCN1CCN(CC1)c1ncccn1)c1nc2ccccc2s1
Show InChI InChI=1S/C19H21N5OS/c25-16(18-22-15-5-1-2-7-17(15)26-18)6-3-10-23-11-13-24(14-12-23)19-20-8-4-9-21-19/h1-2,4-5,7-9H,3,6,10-14H2
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2.21E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384968
PNG
(CHEMBL2037430)
Show SMILES Clc1ccc(cc1)N1CCN(CCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C20H22ClN3S/c21-16-7-9-17(10-8-16)24-14-12-23(13-15-24)11-3-6-20-22-18-4-1-2-5-19(18)25-20/h1-2,4-5,7-10H,3,6,11-15H2
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2.32E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50384960
PNG
(CHEMBL2037519)
Show SMILES O=C(CCCN1CCN(CC1)c1ncccn1)c1nc2ccccc2s1
Show InChI InChI=1S/C19H21N5OS/c25-16(18-22-15-5-1-2-7-17(15)26-18)6-3-10-23-11-13-24(14-12-23)19-20-8-4-9-21-19/h1-2,4-5,7-9H,3,6,10-14H2
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2.47E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50363899
PNG
(CHEMBL1946257)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C23H26ClN3OS/c24-18-9-11-19(12-10-18)27-15-5-14-26(16-17-27)13-4-3-7-21(28)23-25-20-6-1-2-8-22(20)29-23/h1-2,6,8-12H,3-5,7,13-17H2
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2.81E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50384964
PNG
(CHEMBL2037528)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H24ClN3OS/c23-17-8-10-18(11-9-17)26-15-13-25(14-16-26)12-4-3-6-20(27)22-24-19-5-1-2-7-21(19)28-22/h1-2,5,7-11H,3-4,6,12-16H2
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2.92E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384963
PNG
(CHEMBL2037527)
Show SMILES O=C(CCCCN1Cc2ccccc2C1)c1nc2ccccc2s1
Show InChI InChI=1S/C20H20N2OS/c23-18(20-21-17-9-3-4-11-19(17)24-20)10-5-6-12-22-13-15-7-1-2-8-16(15)14-22/h1-4,7-9,11H,5-6,10,12-14H2
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2.93E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384962
PNG
(CHEMBL2037526)
Show SMILES O=C(CCCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C25H28N4O2S/c30-21(23-27-20-10-4-5-12-22(20)32-23)11-6-7-15-28-16-13-25(14-17-28)24(31)26-18-29(25)19-8-2-1-3-9-19/h1-5,8-10,12H,6-7,11,13-18H2,(H,26,31)
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3.72E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 2C (5-HT2C)


(Homo sapiens (human))
BDBM50384967
PNG
(CHEMBL2037531)
Show SMILES O=C(CCCCN1CCC(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C23H26N2OS/c26-21(23-24-20-10-4-5-12-22(20)27-23)11-6-7-15-25-16-13-19(14-17-25)18-8-2-1-3-9-18/h1-5,8-10,12,19H,6-7,11,13-17H2
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3.74E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Binding affinity to human 5HT2C receptor by radioligand displacement assay


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384955
PNG
(CHEMBL2037522)
Show SMILES C(CCc1nc2ccccc2s1)CN1CCc2ccccc2C1
Show InChI InChI=1S/C20H22N2S/c1-2-8-17-15-22(14-12-16(17)7-1)13-6-5-11-20-21-18-9-3-4-10-19(18)23-20/h1-4,7-10H,5-6,11-15H2
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3.81E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384970
PNG
(CHEMBL2037432)
Show SMILES OC1(CCN(CCCCc2nc3ccccc3s2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H25ClN2OS/c23-18-10-8-17(9-11-18)22(26)12-15-25(16-13-22)14-4-3-7-21-24-19-5-1-2-6-20(19)27-21/h1-2,5-6,8-11,26H,3-4,7,12-16H2
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4.26E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 2C (5-HT2C)


(Homo sapiens (human))
BDBM50384968
PNG
(CHEMBL2037430)
Show SMILES Clc1ccc(cc1)N1CCN(CCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C20H22ClN3S/c21-16-7-9-17(10-8-16)24-14-12-23(13-15-24)11-3-6-20-22-18-4-1-2-5-19(18)25-20/h1-2,4-5,7-10H,3,6,11-15H2
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4.65E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Binding affinity to human 5HT2C receptor by radioligand displacement assay


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (human))
BDBM50384964
PNG
(CHEMBL2037528)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H24ClN3OS/c23-17-8-10-18(11-9-17)26-15-13-25(14-16-26)12-4-3-6-20(27)22-24-19-5-1-2-7-21(19)28-22/h1-2,5,7-11H,3-4,6,12-16H2
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4.74E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]GBR12935 from human DAT by liquid scintillation assay


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384964
PNG
(CHEMBL2037528)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H24ClN3OS/c23-17-8-10-18(11-9-17)26-15-13-25(14-16-26)12-4-3-6-20(27)22-24-19-5-1-2-7-21(19)28-22/h1-2,5,7-11H,3-4,6,12-16H2
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4.79E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 2C (5-HT2C)


(Homo sapiens (human))
BDBM50363899
PNG
(CHEMBL1946257)
Show SMILES Clc1ccc(cc1)N1CCCN(CCCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C23H26ClN3OS/c24-18-9-11-19(12-10-18)27-15-5-14-26(16-17-27)13-4-3-7-21(28)23-25-20-6-1-2-8-22(20)29-23/h1-2,6,8-12H,3-5,7,13-17H2
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5.92E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Binding affinity to human 5HT2C receptor by radioligand displacement assay


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 2C (5-HT2C)


(Homo sapiens (human))
BDBM50384969
PNG
(CHEMBL2037431)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H24ClN3S/c22-17-8-10-18(11-9-17)25-15-13-24(14-16-25)12-4-3-7-21-23-19-5-1-2-6-20(19)26-21/h1-2,5-6,8-11H,3-4,7,12-16H2
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6.21E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Binding affinity to human 5HT2C receptor by radioligand displacement assay


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 2C (5-HT2C)


(Homo sapiens (human))
BDBM50384955
PNG
(CHEMBL2037522)
Show SMILES C(CCc1nc2ccccc2s1)CN1CCc2ccccc2C1
Show InChI InChI=1S/C20H22N2S/c1-2-8-17-15-22(14-12-16(17)7-1)13-6-5-11-20-21-18-9-3-4-10-19(18)23-20/h1-4,7-10H,5-6,11-15H2
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6.27E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Binding affinity to human 5HT2C receptor by radioligand displacement assay


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384965
PNG
(CHEMBL2037529)
Show SMILES O=C(CCCCN1CCN(CC1)c1ncccn1)c1nc2ccccc2s1
Show InChI InChI=1S/C20H23N5OS/c26-17(19-23-16-6-1-2-8-18(16)27-19)7-3-4-11-24-12-14-25(15-13-24)20-21-9-5-10-22-20/h1-2,5-6,8-10H,3-4,7,11-15H2
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6.98E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384957
PNG
(CHEMBL2037524)
Show SMILES Clc1ccc(cc1)N1CCN(CCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H22ClN3OS/c22-16-7-9-17(10-8-16)25-14-12-24(13-15-25)11-3-5-19(26)21-23-18-4-1-2-6-20(18)27-21/h1-2,4,6-10H,3,5,11-15H2
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8.36E+3n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50384958
PNG
(CHEMBL2037525)
Show SMILES O=C(CCCN1CCN(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C21H23N3OS/c25-19(21-22-18-9-4-5-11-20(18)26-21)10-6-12-23-13-15-24(16-14-23)17-7-2-1-3-8-17/h1-5,7-9,11H,6,10,12-16H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Citalopram from human SERT by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384963
PNG
(CHEMBL2037527)
Show SMILES O=C(CCCCN1Cc2ccccc2C1)c1nc2ccccc2s1
Show InChI InChI=1S/C20H20N2OS/c23-18(20-21-17-9-3-4-11-19(17)24-20)10-5-6-12-22-13-15-7-1-2-8-16(15)14-22/h1-4,7-9,11H,5-6,10,12-14H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM50384957
PNG
(CHEMBL2037524)
Show SMILES Clc1ccc(cc1)N1CCN(CCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C21H22ClN3OS/c22-16-7-9-17(10-8-16)25-14-12-24(13-15-25)11-3-5-19(26)21-23-18-4-1-2-6-20(18)27-21/h1-2,4,6-10H,3,5,11-15H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
Sodium-dependent noradrenaline transporter


(Homo sapiens (human))
BDBM50384964
PNG
(CHEMBL2037528)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCC(=O)c2nc3ccccc3s2)CC1
Show InChI InChI=1S/C22H24ClN3OS/c23-17-8-10-18(11-9-17)26-15-13-25(14-16-26)12-4-3-6-20(27)22-24-19-5-1-2-7-21(19)28-22/h1-2,5,7-11H,3-4,6,12-16H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Nisoxetine from human NET by liquid scintillation assay


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 2C (5-HT2C)


(Homo sapiens (human))
BDBM50384954
PNG
(CHEMBL2037521)
Show SMILES C(CCc1nc2ccccc2s1)CN1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C19H23N5S/c1-2-7-17-16(6-1)22-18(25-17)8-3-4-11-23-12-14-24(15-13-23)19-20-9-5-10-21-19/h1-2,5-7,9-10H,3-4,8,11-15H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Binding affinity to human 5HT2C receptor by radioligand displacement assay


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384958
PNG
(CHEMBL2037525)
Show SMILES O=C(CCCN1CCN(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C21H23N3OS/c25-19(21-22-18-9-4-5-11-20(18)26-21)10-6-12-23-13-15-24(16-14-23)17-7-2-1-3-8-17/h1-5,7-9,11H,6,10,12-16H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50384958
PNG
(CHEMBL2037525)
Show SMILES O=C(CCCN1CCN(CC1)c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C21H23N3OS/c25-19(21-22-18-9-4-5-11-20(18)26-21)10-6-12-23-13-15-24(16-14-23)17-7-2-1-3-8-17/h1-5,7-9,11H,6,10,12-16H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50384956
PNG
(CHEMBL2037523)
Show SMILES C(CCc1nc2ccccc2s1)CN1Cc2ccccc2C1
Show InChI InChI=1S/C19H20N2S/c1-2-8-16-14-21(13-15(16)7-1)12-6-5-11-19-20-17-9-3-4-10-18(17)22-19/h1-4,7-10H,5-6,11-14H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Florida A&M University

Curated by ChEMBL


Assay Description
Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting


Eur J Med Chem 53: 124-32 (2012)


Article DOI: 10.1016/j.ejmech.2012.03.042
BindingDB Entry DOI: 10.7270/Q2PN96NS
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%