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PubMed code 22543026

Compile data set for download or QSAR
Found 6 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase PIM


(Homo sapiens (Human))
BDBM50385115
PNG
(CHEMBL2036116)
Show SMILES O=Cc1c[nH]c2c1ccc1c3ccccc3n(CCCCC#N)c21
Show InChI InChI=1S/C20H17N3O/c21-10-4-1-5-11-23-18-7-3-2-6-16(18)17-9-8-15-14(13-24)12-22-19(15)20(17)23/h2-3,6-9,12-13,22H,1,4-5,11H2
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 41n/an/an/an/an/an/a



Clermont Universit£

Curated by ChEMBL


Assay Description
Inhibition of Pim-3 using RSRHSSYPAGT as substrate after 30 mins


Bioorg Med Chem Lett 22: 3807-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.098
BindingDB Entry DOI: 10.7270/Q2HX1DQB
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PIM


(Homo sapiens (Human))
BDBM50385115
PNG
(CHEMBL2036116)
Show SMILES O=Cc1c[nH]c2c1ccc1c3ccccc3n(CCCCC#N)c21
Show InChI InChI=1S/C20H17N3O/c21-10-4-1-5-11-23-18-7-3-2-6-16(18)17-9-8-15-14(13-24)12-22-19(15)20(17)23/h2-3,6-9,12-13,22H,1,4-5,11H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 46n/an/an/an/an/an/a



Clermont Universit£

Curated by ChEMBL


Assay Description
Inhibition of Pim-1 using RSRHSSYPAGT as substrate after 30 mins


Bioorg Med Chem Lett 22: 3807-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.098
BindingDB Entry DOI: 10.7270/Q2HX1DQB
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PIM


(Homo sapiens (Human))
BDBM50385117
PNG
(CHEMBL2036118)
Show SMILES CN(C)CCCCn1c2ccccc2c2ccc3c(C=O)c[nH]c3c12
Show InChI InChI=1S/C21H23N3O/c1-23(2)11-5-6-12-24-19-8-4-3-7-17(19)18-10-9-16-15(14-25)13-22-20(16)21(18)24/h3-4,7-10,13-14,22H,5-6,11-12H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 75n/an/an/an/an/an/a



Clermont Universit£

Curated by ChEMBL


Assay Description
Inhibition of Pim-1 using RSRHSSYPAGT as substrate after 30 mins


Bioorg Med Chem Lett 22: 3807-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.098
BindingDB Entry DOI: 10.7270/Q2HX1DQB
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PIM


(Homo sapiens (Human))
BDBM50385117
PNG
(CHEMBL2036118)
Show SMILES CN(C)CCCCn1c2ccccc2c2ccc3c(C=O)c[nH]c3c12
Show InChI InChI=1S/C21H23N3O/c1-23(2)11-5-6-12-24-19-8-4-3-7-17(19)18-10-9-16-15(14-25)13-22-20(16)21(18)24/h3-4,7-10,13-14,22H,5-6,11-12H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 80n/an/an/an/an/an/a



Clermont Universit£

Curated by ChEMBL


Assay Description
Inhibition of Pim-3 using RSRHSSYPAGT as substrate after 30 mins


Bioorg Med Chem Lett 22: 3807-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.098
BindingDB Entry DOI: 10.7270/Q2HX1DQB
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PIM


(Homo sapiens (Human))
BDBM50385116
PNG
(CHEMBL2036117)
Show SMILES CC(C)(C)OC(=O)NCCCCn1c2ccccc2c2ccc3c(C=O)c[nH]c3c12
Show InChI InChI=1S/C24H27N3O3/c1-24(2,3)30-23(29)25-12-6-7-13-27-20-9-5-4-8-18(20)19-11-10-17-16(15-28)14-26-21(17)22(19)27/h4-5,8-11,14-15,26H,6-7,12-13H2,1-3H3,(H,25,29)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Clermont Universit£

Curated by ChEMBL


Assay Description
Inhibition of Pim-3 using RSRHSSYPAGT as substrate after 30 mins


Bioorg Med Chem Lett 22: 3807-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.098
BindingDB Entry DOI: 10.7270/Q2HX1DQB
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PIM


(Homo sapiens (Human))
BDBM50385116
PNG
(CHEMBL2036117)
Show SMILES CC(C)(C)OC(=O)NCCCCn1c2ccccc2c2ccc3c(C=O)c[nH]c3c12
Show InChI InChI=1S/C24H27N3O3/c1-24(2,3)30-23(29)25-12-6-7-13-27-20-9-5-4-8-18(20)19-11-10-17-16(15-28)14-26-21(17)22(19)27/h4-5,8-11,14-15,26H,6-7,12-13H2,1-3H3,(H,25,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 470n/an/an/an/an/an/a



Clermont Universit£

Curated by ChEMBL


Assay Description
Inhibition of Pim-1 using RSRHSSYPAGT as substrate after 30 mins


Bioorg Med Chem Lett 22: 3807-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.098
BindingDB Entry DOI: 10.7270/Q2HX1DQB
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%