Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50040009
TargetEndothelin-1 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50117910(4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity at endothelin receptor subtype AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50117910(4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)
Affinity DataKi:  10nMAssay Description:Binding affinity at type 1 angiotensin 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387812(CHEMBL2058372)
Affinity DataIC50:  8.5nMAssay Description:Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061101(4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-...)
Affinity DataIC50:  8.90nMAssay Description:Antagonist activity at human endothelin receptor subtype A expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387812(CHEMBL2058372)
Affinity DataIC50:  8.90nMAssay Description:Antagonist activity at human endothelin receptor subtype A expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387811(CHEMBL2058371)
Affinity DataIC50:  9.10nMAssay Description:Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387811(CHEMBL2058371)
Affinity DataIC50:  9.30nMAssay Description:Antagonist activity at human endothelin receptor subtype A expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387805(CHEMBL2058373)
Affinity DataIC50:  9.60nMAssay Description:Antagonist activity at human endothelin receptor subtype A expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387805(CHEMBL2058373)
Affinity DataIC50:  9.80nMAssay Description:Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387813(CHEMBL2058374)
Affinity DataIC50:  9.80nMAssay Description:Antagonist activity at human endothelin receptor subtype A expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387810(CHEMBL2058370)
Affinity DataIC50:  9.80nMAssay Description:Antagonist activity at human endothelin receptor subtype A expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387810(CHEMBL2058370)
Affinity DataIC50:  9.90nMAssay Description:Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387813(CHEMBL2058374)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387815(CHEMBL2058376)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human endothelin receptor subtype A expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387814(CHEMBL2058375)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human endothelin receptor subtype A expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387814(CHEMBL2058375)
Affinity DataIC50:  10.5nMAssay Description:Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387816(CHEMBL2058377)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human endothelin receptor subtype A expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387815(CHEMBL2058376)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387816(CHEMBL2058377)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50117909(CHEMBL278176 | N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at type 1 angiotensin 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387809(CHEMBL2058369)
Affinity DataIC50:  16nMAssay Description:Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387809(CHEMBL2058369)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human endothelin receptor subtype A expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50117909(CHEMBL278176 | N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-...)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at endothelin receptor subtype AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387808(CHEMBL2058368)
Affinity DataIC50:  28nMAssay Description:Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387808(CHEMBL2058368)
Affinity DataIC50:  39nMAssay Description:Antagonist activity at human endothelin receptor subtype A expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387807(CHEMBL2058367)
Affinity DataIC50:  45nMAssay Description:Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387807(CHEMBL2058367)
Affinity DataIC50:  75nMAssay Description:Antagonist activity at human endothelin receptor subtype A expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387806(CHEMBL2058366)
Affinity DataIC50:  92nMAssay Description:Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM82258(CAS_114798-26-4 | Losartan | NSC_3961)
Affinity DataIC50:  95nMAssay Description:Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50387806(CHEMBL2058366)
Affinity DataIC50:  99nMAssay Description:Antagonist activity at human endothelin receptor subtype A expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed