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Found 6 Enz. Inhib. hit(s) with all data for entry = 50042502
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50426931(CHEMBL2323729 | US20230365568, Compound 6a)
Affinity DataIC50:  5.27E+3nMAssay Description:Inhibition of Plk1 polo-box domain in human HeLa cells/biotin-GGGGG-PLHSpT interaction incubated for 30 mins measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  2.24E+4nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged Plk1 in presence of 62.5 uM of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.29E+5nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged Plk1 in presence of 3.12 mM of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50426930(CHEMBL2324036)
Affinity DataIC50:  1.39E+5nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged Plk1 in presence of 3.12 mM of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50426930(CHEMBL2324036)
Affinity DataIC50:  1.46E+5nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged Plk1 in presence of 62.5 uM of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50426930(CHEMBL2324036)
Affinity DataIC50:  1.51E+5nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged Plk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed