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PubMed code 23352754

Compile data set for download or QSAR
Found 28 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 12


(Homo sapiens (human))
BDBM10880
PNG
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
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5.60n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-12-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase


(Homo sapiens (human))
BDBM50429222
PNG
(CHEMBL2331569)
Show SMILES NS(=O)(=O)c1ccc(CCN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1
Show InChI InChI=1S/C14H14N2O6S3/c15-23(17,18)12-7-5-11(6-8-12)9-10-16-24(19,20)13-3-1-2-4-14(13)25(16,21)22/h1-8H,9-10H2,(H2,15,17,18)
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7.20n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-1-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM10880
PNG
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
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12n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-2-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM50429224
PNG
(CHEMBL2332769)
Show SMILES NS(=O)(=O)c1ccc(N2S(=O)(=O)c3ccccc3S2(=O)=O)c(Cl)c1
Show InChI InChI=1S/C12H9ClN2O6S3/c13-9-7-8(22(14,16)17)5-6-10(9)15-23(18,19)11-3-1-2-4-12(11)24(15,20)21/h1-7H,(H2,14,16,17)
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17n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-9-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (human))
BDBM50429225
PNG
(CHEMBL2332770)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1S(=O)(=O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-7-5-9(6-8-10)14-22(17,18)11-3-1-2-4-12(11)23(14,19)20/h1-8H,(H2,13,15,16)
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19n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-12-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM10880
PNG
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
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25n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-9-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM50429222
PNG
(CHEMBL2331569)
Show SMILES NS(=O)(=O)c1ccc(CCN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1
Show InChI InChI=1S/C14H14N2O6S3/c15-23(17,18)12-7-5-11(6-8-12)9-10-16-24(19,20)13-3-1-2-4-14(13)25(16,21)22/h1-8H,9-10H2,(H2,15,17,18)
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27n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-2-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM50429223
PNG
(CHEMBL2332768)
Show SMILES NS(=O)(=O)c1ccc(CN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1
Show InChI InChI=1S/C13H12N2O6S3/c14-22(16,17)11-7-5-10(6-8-11)9-15-23(18,19)12-3-1-2-4-13(12)24(15,20)21/h1-8H,9H2,(H2,14,16,17)
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27n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-1-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM50429223
PNG
(CHEMBL2332768)
Show SMILES NS(=O)(=O)c1ccc(CN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1
Show InChI InChI=1S/C13H12N2O6S3/c14-22(16,17)11-7-5-10(6-8-11)9-15-23(18,19)12-3-1-2-4-13(12)24(15,20)21/h1-8H,9H2,(H2,14,16,17)
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28n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-2-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (human))
BDBM50429223
PNG
(CHEMBL2332768)
Show SMILES NS(=O)(=O)c1ccc(CN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1
Show InChI InChI=1S/C13H12N2O6S3/c14-22(16,17)11-7-5-10(6-8-11)9-15-23(18,19)12-3-1-2-4-13(12)24(15,20)21/h1-8H,9H2,(H2,14,16,17)
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31n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-12-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM50429226
PNG
(CHEMBL2332771)
Show SMILES NS(=O)(=O)c1cccc(c1)N1S(=O)(=O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-5-3-4-9(8-10)14-22(17,18)11-6-1-2-7-12(11)23(14,19)20/h1-8H,(H2,13,15,16)
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31n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-1-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM50429226
PNG
(CHEMBL2332771)
Show SMILES NS(=O)(=O)c1cccc(c1)N1S(=O)(=O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-5-3-4-9(8-10)14-22(17,18)11-6-1-2-7-12(11)23(14,19)20/h1-8H,(H2,13,15,16)
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32n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-9-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (human))
BDBM50429222
PNG
(CHEMBL2331569)
Show SMILES NS(=O)(=O)c1ccc(CCN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1
Show InChI InChI=1S/C14H14N2O6S3/c15-23(17,18)12-7-5-11(6-8-12)9-10-16-24(19,20)13-3-1-2-4-14(13)25(16,21)22/h1-8H,9-10H2,(H2,15,17,18)
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32n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-12-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (human))
BDBM50429224
PNG
(CHEMBL2332769)
Show SMILES NS(=O)(=O)c1ccc(N2S(=O)(=O)c3ccccc3S2(=O)=O)c(Cl)c1
Show InChI InChI=1S/C12H9ClN2O6S3/c13-9-7-8(22(14,16)17)5-6-10(9)15-23(18,19)11-3-1-2-4-12(11)24(15,20)21/h1-7H,(H2,14,16,17)
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35n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-12-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM50429224
PNG
(CHEMBL2332769)
Show SMILES NS(=O)(=O)c1ccc(N2S(=O)(=O)c3ccccc3S2(=O)=O)c(Cl)c1
Show InChI InChI=1S/C12H9ClN2O6S3/c13-9-7-8(22(14,16)17)5-6-10(9)15-23(18,19)11-3-1-2-4-12(11)24(15,20)21/h1-7H,(H2,14,16,17)
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36n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-1-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM50429225
PNG
(CHEMBL2332770)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1S(=O)(=O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-7-5-9(6-8-10)14-22(17,18)11-3-1-2-4-12(11)23(14,19)20/h1-8H,(H2,13,15,16)
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49n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-1-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM50429223
PNG
(CHEMBL2332768)
Show SMILES NS(=O)(=O)c1ccc(CN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1
Show InChI InChI=1S/C13H12N2O6S3/c14-22(16,17)11-7-5-10(6-8-11)9-15-23(18,19)12-3-1-2-4-13(12)24(15,20)21/h1-8H,9H2,(H2,14,16,17)
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50n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-9-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM50429227
PNG
(CHEMBL2332772)
Show SMILES NS(=O)(=O)c1ccccc1N1S(=O)(=O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-6-2-1-5-9(10)14-22(17,18)11-7-3-4-8-12(11)23(14,19)20/h1-8H,(H2,13,15,16)
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51n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-1-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (human))
BDBM50429227
PNG
(CHEMBL2332772)
Show SMILES NS(=O)(=O)c1ccccc1N1S(=O)(=O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-6-2-1-5-9(10)14-22(17,18)11-7-3-4-8-12(11)23(14,19)20/h1-8H,(H2,13,15,16)
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51n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-12-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM50429225
PNG
(CHEMBL2332770)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1S(=O)(=O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-7-5-9(6-8-10)14-22(17,18)11-3-1-2-4-12(11)23(14,19)20/h1-8H,(H2,13,15,16)
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55n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-2-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM50429224
PNG
(CHEMBL2332769)
Show SMILES NS(=O)(=O)c1ccc(N2S(=O)(=O)c3ccccc3S2(=O)=O)c(Cl)c1
Show InChI InChI=1S/C12H9ClN2O6S3/c13-9-7-8(22(14,16)17)5-6-10(9)15-23(18,19)11-3-1-2-4-12(11)24(15,20)21/h1-7H,(H2,14,16,17)
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62n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-2-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM50429226
PNG
(CHEMBL2332771)
Show SMILES NS(=O)(=O)c1cccc(c1)N1S(=O)(=O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-5-3-4-9(8-10)14-22(17,18)11-6-1-2-7-12(11)23(14,19)20/h1-8H,(H2,13,15,16)
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62n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-2-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM50429227
PNG
(CHEMBL2332772)
Show SMILES NS(=O)(=O)c1ccccc1N1S(=O)(=O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-6-2-1-5-9(10)14-22(17,18)11-7-3-4-8-12(11)23(14,19)20/h1-8H,(H2,13,15,16)
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67n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-9-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (human))
BDBM50429226
PNG
(CHEMBL2332771)
Show SMILES NS(=O)(=O)c1cccc(c1)N1S(=O)(=O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-5-3-4-9(8-10)14-22(17,18)11-6-1-2-7-12(11)23(14,19)20/h1-8H,(H2,13,15,16)
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72n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-12-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM50429225
PNG
(CHEMBL2332770)
Show SMILES NS(=O)(=O)c1ccc(cc1)N1S(=O)(=O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-7-5-9(6-8-10)14-22(17,18)11-3-1-2-4-12(11)23(14,19)20/h1-8H,(H2,13,15,16)
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83n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-9-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM50429222
PNG
(CHEMBL2331569)
Show SMILES NS(=O)(=O)c1ccc(CCN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1
Show InChI InChI=1S/C14H14N2O6S3/c15-23(17,18)12-7-5-11(6-8-12)9-10-16-24(19,20)13-3-1-2-4-14(13)25(16,21)22/h1-8H,9-10H2,(H2,15,17,18)
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86n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-9-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM50429227
PNG
(CHEMBL2332772)
Show SMILES NS(=O)(=O)c1ccccc1N1S(=O)(=O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C12H10N2O6S3/c13-21(15,16)10-6-2-1-5-9(10)14-22(17,18)11-7-3-4-8-12(11)23(14,19)20/h1-8H,(H2,13,15,16)
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96n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-2-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM10880
PNG
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
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250n/an/an/an/an/an/an/an/a



Istanbul University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase-1-mediated CO2 hydration preincubated for 10 mins by stopped-flow assay


Bioorg Med Chem 21: 1386-91 (2013)


Article DOI: 10.1016/j.bmc.2012.12.037
BindingDB Entry DOI: 10.7270/Q2474C61
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
* indicates data uncertainty>20%