BindingDB PrimarySearch_ki

Found 26 Enz. Inhib. hit(s) with all data for entry = 50042704

Serine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50348452(AZD-8055 | CHEMBL1801204 | US9102670, 1a)

IC50: 0.130nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR (1362 to 2549) (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Serine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50310989((5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholin...)

IC50: 2.5nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR (1362 to 2549) (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Serine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429701(AZD-2014 | CHEMBL2336325 | US9102670, 1ap)

IC50: 2.80nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR (1362 to 2549) (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429717(CHEMBL2336331 | US9102670, 1j)

IC50: 4.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50310989((5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholin...)

IC50: 5.30E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using lipid PIP2 as substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429716(CHEMBL2336332 | US9102670, 18bn)

IC50: 8.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50310989((5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholin...)

IC50: 8.30E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50310989((5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholin...)

IC50: 8.90E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using lipid PIP2 as substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429715(CHEMBL2336328)

IC50: 1.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429714(CHEMBL2331605 | US9102670, 12a)

IC50: 1.32E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429713(CHEMBL2336334 | US9102670, 18ax)

IC50: 1.70E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429712(CHEMBL2336329)

IC50: 1.74E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429711(CHEMBL2336323 | US9102670, 1dh)

IC50: 2.42E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429710(CHEMBL2336327)

IC50: 2.75E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50310989((5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholin...)

IC50: >3.00E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using lipid PIP2 as substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50310989((5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholin...)

IC50: >3.00E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using lipid PIP2 as substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50348452(AZD-8055 | CHEMBL1801204 | US9102670, 1a)

IC50: 3.04E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429709(CHEMBL2336333 | US9102670, 18cg)

IC50: >3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429708(CHEMBL2336318 | US9102670, 18ay)

IC50: >3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429707(CHEMBL2336319)

IC50: >3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429706(CHEMBL2336320 | US9102670, 14b)

IC50: >3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429703(CHEMBL2336324 | US9102670, 1cl)

IC50: >3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429704(CHEMBL2336322 | US9102670, 3t)

IC50: >3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429705(CHEMBL2336321 | US9102670, 3ad)

IC50: >3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429702(CHEMBL2336326 | US9102670, 8a)

IC50: >3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar

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Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

PNG

BDBM50429701(AZD-2014 | CHEMBL2336325 | US9102670, 1ap)

IC50: 4.75E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar

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