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PubMed code 23453843

Compile data set for download or QSAR
Found 84 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50431996
PNG
(CHEMBL2348724)
Show SMILES Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C8H7N3O/c9-7-5-3-1-2-4-6(5)8(12)11-10-7/h1-4H,(H2,9,10)(H,11,12)
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n/an/a 4.10E+3n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432008
PNG
(CHEMBL2348735)
Show SMILES Nc1cc(-c2ccccc2)c(=O)[nH]n1
Show InChI InChI=1S/C10H9N3O/c11-9-6-8(10(14)13-12-9)7-4-2-1-3-5-7/h1-6H,(H2,11,12)(H,13,14)
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n/an/a 6.00E+3n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50431997
PNG
(CHEMBL2348723)
Show SMILES CC(C)C(=O)Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C12H13N3O2/c1-7(2)11(16)13-10-8-5-3-4-6-9(8)12(17)15-14-10/h3-7H,1-2H3,(H,15,17)(H,13,14,16)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432000
PNG
(CHEMBL2348743)
Show SMILES CCCCCC(=O)Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C14H17N3O2/c1-2-3-4-9-12(18)15-13-10-7-5-6-8-11(10)14(19)17-16-13/h5-8H,2-4,9H2,1H3,(H,17,19)(H,15,16,18)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432005
PNG
(CHEMBL2348738)
Show SMILES CCCCCC(=O)N(C(=O)CCCCC)c1nnc(Cl)c2ccccc12
Show InChI InChI=1S/C20H26ClN3O2/c1-3-5-7-13-17(25)24(18(26)14-8-6-4-2)20-16-12-10-9-11-15(16)19(21)22-23-20/h9-12H,3-8,13-14H2,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432010
PNG
(CHEMBL2348733)
Show SMILES Nc1n[nH]c(=O)cc1-c1ccccc1
Show InChI InChI=1S/C10H9N3O/c11-10-8(6-9(14)12-13-10)7-4-2-1-3-5-7/h1-6H,(H2,11,13)(H,12,14)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432018
PNG
(CHEMBL2348750)
Show SMILES O=c1[nH]nc(NCCN2CCCCC2)cc1-c1ccccc1
Show InChI InChI=1S/C17H22N4O/c22-17-15(14-7-3-1-4-8-14)13-16(19-20-17)18-9-12-21-10-5-2-6-11-21/h1,3-4,7-8,13H,2,5-6,9-12H2,(H,18,19)(H,20,22)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50431992
PNG
(CHEMBL2348748)
Show SMILES CCCNc1cc(-c2ccccc2)c(=O)[nH]n1
Show InChI InChI=1S/C13H15N3O/c1-2-8-14-12-9-11(13(17)16-15-12)10-6-4-3-5-7-10/h3-7,9H,2,8H2,1H3,(H,14,15)(H,16,17)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432000
PNG
(CHEMBL2348743)
Show SMILES CCCCCC(=O)Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C14H17N3O2/c1-2-3-4-9-12(18)15-13-10-7-5-6-8-11(10)14(19)17-16-13/h5-8H,2-4,9H2,1H3,(H,17,19)(H,15,16,18)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432014
PNG
(CHEMBL2348729)
Show SMILES CCCNc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C11H13N3O/c1-2-7-12-10-8-5-3-4-6-9(8)11(15)14-13-10/h3-6H,2,7H2,1H3,(H,12,13)(H,14,15)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432017
PNG
(CHEMBL2348726)
Show SMILES O=c1cc(c(NCCN2CCCCC2)n[nH]1)-c1ccccc1
Show InChI InChI=1S/C17H22N4O/c22-16-13-15(14-7-3-1-4-8-14)17(20-19-16)18-9-12-21-10-5-2-6-11-21/h1,3-4,7-8,13H,2,5-6,9-12H2,(H,18,20)(H,19,22)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432003
PNG
(CHEMBL2348740)
Show SMILES Clc1nnc(NC(=O)Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C16H12ClN3O/c17-15-12-8-4-5-9-13(12)16(20-19-15)18-14(21)10-11-6-2-1-3-7-11/h1-9H,10H2,(H,18,20,21)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432011
PNG
(CHEMBL2348732)
Show SMILES CC(=O)Nc1n[nH]c(=O)cc1-c1ccccc1
Show InChI InChI=1S/C12H11N3O2/c1-8(16)13-12-10(7-11(17)14-15-12)9-5-3-2-4-6-9/h2-7H,1H3,(H,14,17)(H,13,15,16)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432012
PNG
(CHEMBL2348731)
Show SMILES CN1CCC(CC1)Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C14H18N4O/c1-18-8-6-10(7-9-18)15-13-11-4-2-3-5-12(11)14(19)17-16-13/h2-5,10H,6-9H2,1H3,(H,15,16)(H,17,19)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432016
PNG
(CHEMBL2348727)
Show SMILES CN1CCC(CC1)Nc1cc(-c2ccccc2)c(=O)[nH]n1
Show InChI InChI=1S/C16H20N4O/c1-20-9-7-13(8-10-20)17-15-11-14(16(21)19-18-15)12-5-3-2-4-6-12/h2-6,11,13H,7-10H2,1H3,(H,17,18)(H,19,21)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432018
PNG
(CHEMBL2348750)
Show SMILES O=c1[nH]nc(NCCN2CCCCC2)cc1-c1ccccc1
Show InChI InChI=1S/C17H22N4O/c22-17-15(14-7-3-1-4-8-14)13-16(19-20-17)18-9-12-21-10-5-2-6-11-21/h1,3-4,7-8,13H,2,5-6,9-12H2,(H,18,19)(H,20,22)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50431992
PNG
(CHEMBL2348748)
Show SMILES CCCNc1cc(-c2ccccc2)c(=O)[nH]n1
Show InChI InChI=1S/C13H15N3O/c1-2-8-14-12-9-11(13(17)16-15-12)10-6-4-3-5-7-10/h3-7,9H,2,8H2,1H3,(H,14,15)(H,16,17)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50431993
PNG
(CHEMBL2348747)
Show SMILES O=c1cc(c(NCc2ccccc2)n[nH]1)-c1ccccc1
Show InChI InChI=1S/C17H15N3O/c21-16-11-15(14-9-5-2-6-10-14)17(20-19-16)18-12-13-7-3-1-4-8-13/h1-11H,12H2,(H,18,20)(H,19,21)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432016
PNG
(CHEMBL2348727)
Show SMILES CN1CCC(CC1)Nc1cc(-c2ccccc2)c(=O)[nH]n1
Show InChI InChI=1S/C16H20N4O/c1-20-9-7-13(8-10-20)17-15-11-14(16(21)19-18-15)12-5-3-2-4-6-12/h2-6,11,13H,7-10H2,1H3,(H,17,18)(H,19,21)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50431994
PNG
(CHEMBL2348746)
Show SMILES O=c1[nH]nc(NCc2ccccc2)cc1-c1ccccc1
Show InChI InChI=1S/C17H15N3O/c21-17-15(14-9-5-2-6-10-14)11-16(19-20-17)18-12-13-7-3-1-4-8-13/h1-11H,12H2,(H,18,19)(H,20,21)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50431997
PNG
(CHEMBL2348723)
Show SMILES CC(C)C(=O)Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C12H13N3O2/c1-7(2)11(16)13-10-8-5-3-4-6-9(8)12(17)15-14-10/h3-7H,1-2H3,(H,15,17)(H,13,14,16)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432006
PNG
(CHEMBL2348737)
Show SMILES O=C(Nc1cc(-c2ccccc2)c(=O)[nH]n1)c1ccccc1
Show InChI InChI=1S/C17H13N3O2/c21-16(13-9-5-2-6-10-13)18-15-11-14(17(22)20-19-15)12-7-3-1-4-8-12/h1-11H,(H,20,22)(H,18,19,21)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50431998
PNG
(CHEMBL2348745)
Show SMILES CC(=O)Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C10H9N3O2/c1-6(14)11-9-7-4-2-3-5-8(7)10(15)13-12-9/h2-5H,1H3,(H,13,15)(H,11,12,14)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432008
PNG
(CHEMBL2348735)
Show SMILES Nc1cc(-c2ccccc2)c(=O)[nH]n1
Show InChI InChI=1S/C10H9N3O/c11-9-6-8(10(14)13-12-9)7-4-2-1-3-5-7/h1-6H,(H2,11,12)(H,13,14)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432014
PNG
(CHEMBL2348729)
Show SMILES CCCNc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C11H13N3O/c1-2-7-12-10-8-5-3-4-6-9(8)11(15)14-13-10/h3-6H,2,7H2,1H3,(H,12,13)(H,14,15)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432017
PNG
(CHEMBL2348726)
Show SMILES O=c1cc(c(NCCN2CCCCC2)n[nH]1)-c1ccccc1
Show InChI InChI=1S/C17H22N4O/c22-16-13-15(14-7-3-1-4-8-14)17(20-19-16)18-9-12-21-10-5-2-6-11-21/h1,3-4,7-8,13H,2,5-6,9-12H2,(H,18,20)(H,19,22)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50431994
PNG
(CHEMBL2348746)
Show SMILES O=c1[nH]nc(NCc2ccccc2)cc1-c1ccccc1
Show InChI InChI=1S/C17H15N3O/c21-17-15(14-9-5-2-6-10-14)11-16(19-20-17)18-12-13-7-3-1-4-8-13/h1-11H,12H2,(H,18,19)(H,20,21)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50431995
PNG
(CHEMBL2348725)
Show SMILES O=C(Nc1n[nH]c(=O)c2ccccc12)c1ccccc1
Show InChI InChI=1S/C15H11N3O2/c19-14(10-6-2-1-3-7-10)16-13-11-8-4-5-9-12(11)15(20)18-17-13/h1-9H,(H,18,20)(H,16,17,19)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50431996
PNG
(CHEMBL2348724)
Show SMILES Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C8H7N3O/c9-7-5-3-1-2-4-6(5)8(12)11-10-7/h1-4H,(H2,9,10)(H,11,12)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432007
PNG
(CHEMBL2348736)
Show SMILES Clc1nnc(NC(=O)c2ccccc2)cc1-c1ccccc1
Show InChI InChI=1S/C17H12ClN3O/c18-16-14(12-7-3-1-4-8-12)11-15(20-21-16)19-17(22)13-9-5-2-6-10-13/h1-11H,(H,19,20,22)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432015
PNG
(CHEMBL2348728)
Show SMILES O=c1[nH]nc(NCc2ccccc2)c2ccccc12
Show InChI InChI=1S/C15H13N3O/c19-15-13-9-5-4-8-12(13)14(17-18-15)16-10-11-6-2-1-3-7-11/h1-9H,10H2,(H,16,17)(H,18,19)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432019
PNG
(CHEMBL2348749)
Show SMILES CCCNc1n[nH]c(=O)cc1-c1ccccc1
Show InChI InChI=1S/C13H15N3O/c1-2-8-14-13-11(9-12(17)15-16-13)10-6-4-3-5-7-10/h3-7,9H,2,8H2,1H3,(H,14,16)(H,15,17)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432002
PNG
(CHEMBL2348741)
Show SMILES CC(=O)N(C(C)=O)c1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C12H11N3O3/c1-7(16)15(8(2)17)11-9-5-3-4-6-10(9)12(18)14-13-11/h3-6H,1-2H3,(H,14,18)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432015
PNG
(CHEMBL2348728)
Show SMILES O=c1[nH]nc(NCc2ccccc2)c2ccccc12
Show InChI InChI=1S/C15H13N3O/c19-15-13-9-5-4-8-12(13)14(17-18-15)16-10-11-6-2-1-3-7-11/h1-9H,10H2,(H,16,17)(H,18,19)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432003
PNG
(CHEMBL2348740)
Show SMILES Clc1nnc(NC(=O)Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C16H12ClN3O/c17-15-12-8-4-5-9-13(12)16(20-19-15)18-14(21)10-11-6-2-1-3-7-11/h1-9H,10H2,(H,18,20,21)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432006
PNG
(CHEMBL2348737)
Show SMILES O=C(Nc1cc(-c2ccccc2)c(=O)[nH]n1)c1ccccc1
Show InChI InChI=1S/C17H13N3O2/c21-16(13-9-5-2-6-10-13)18-15-11-14(17(22)20-19-15)12-7-3-1-4-8-12/h1-11H,(H,20,22)(H,18,19,21)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432009
PNG
(CHEMBL2348734)
Show SMILES CC(=O)Nc1cc(-c2ccccc2)c(=O)[nH]n1
Show InChI InChI=1S/C12H11N3O2/c1-8(16)13-11-7-10(12(17)15-14-11)9-5-3-2-4-6-9/h2-7H,1H3,(H,15,17)(H,13,14,16)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432003
PNG
(CHEMBL2348740)
Show SMILES Clc1nnc(NC(=O)Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C16H12ClN3O/c17-15-12-8-4-5-9-13(12)16(20-19-15)18-14(21)10-11-6-2-1-3-7-11/h1-9H,10H2,(H,18,20,21)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432005
PNG
(CHEMBL2348738)
Show SMILES CCCCCC(=O)N(C(=O)CCCCC)c1nnc(Cl)c2ccccc12
Show InChI InChI=1S/C20H26ClN3O2/c1-3-5-7-13-17(25)24(18(26)14-8-6-4-2)20-16-12-10-9-11-15(16)19(21)22-23-20/h9-12H,3-8,13-14H2,1-2H3
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432001
PNG
(CHEMBL2348742)
Show SMILES CC(C)C(=O)N(C(=O)C(C)C)c1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C16H19N3O3/c1-9(2)15(21)19(16(22)10(3)4)13-11-7-5-6-8-12(11)14(20)18-17-13/h5-10H,1-4H3,(H,18,20)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432004
PNG
(CHEMBL2348739)
Show SMILES Clc1nnc(N(C(=O)Cc2ccccc2)C(=O)Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C24H18ClN3O2/c25-23-19-13-7-8-14-20(19)24(27-26-23)28(21(29)15-17-9-3-1-4-10-17)22(30)16-18-11-5-2-6-12-18/h1-14H,15-16H2
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432017
PNG
(CHEMBL2348726)
Show SMILES O=c1cc(c(NCCN2CCCCC2)n[nH]1)-c1ccccc1
Show InChI InChI=1S/C17H22N4O/c22-16-13-15(14-7-3-1-4-8-14)17(20-19-16)18-9-12-21-10-5-2-6-11-21/h1,3-4,7-8,13H,2,5-6,9-12H2,(H,18,20)(H,19,22)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50431994
PNG
(CHEMBL2348746)
Show SMILES O=c1[nH]nc(NCc2ccccc2)cc1-c1ccccc1
Show InChI InChI=1S/C17H15N3O/c21-17-15(14-9-5-2-6-10-14)11-16(19-20-17)18-12-13-7-3-1-4-8-13/h1-11H,12H2,(H,18,19)(H,20,21)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432012
PNG
(CHEMBL2348731)
Show SMILES CN1CCC(CC1)Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C14H18N4O/c1-18-8-6-10(7-9-18)15-13-11-4-2-3-5-12(11)14(19)17-16-13/h2-5,10H,6-9H2,1H3,(H,15,16)(H,17,19)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50431997
PNG
(CHEMBL2348723)
Show SMILES CC(C)C(=O)Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C12H13N3O2/c1-7(2)11(16)13-10-8-5-3-4-6-9(8)12(17)15-14-10/h3-7H,1-2H3,(H,15,17)(H,13,14,16)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432010
PNG
(CHEMBL2348733)
Show SMILES Nc1n[nH]c(=O)cc1-c1ccccc1
Show InChI InChI=1S/C10H9N3O/c11-10-8(6-9(14)12-13-10)7-4-2-1-3-5-7/h1-6H,(H2,11,13)(H,12,14)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432018
PNG
(CHEMBL2348750)
Show SMILES O=c1[nH]nc(NCCN2CCCCC2)cc1-c1ccccc1
Show InChI InChI=1S/C17H22N4O/c22-17-15(14-7-3-1-4-8-14)13-16(19-20-17)18-9-12-21-10-5-2-6-11-21/h1,3-4,7-8,13H,2,5-6,9-12H2,(H,18,19)(H,20,22)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50431995
PNG
(CHEMBL2348725)
Show SMILES O=C(Nc1n[nH]c(=O)c2ccccc12)c1ccccc1
Show InChI InChI=1S/C15H11N3O2/c19-14(10-6-2-1-3-7-10)16-13-11-8-4-5-9-12(11)15(20)18-17-13/h1-9H,(H,18,20)(H,16,17,19)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50431999
PNG
(CHEMBL2348744)
Show SMILES O=C(Cc1ccccc1)Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C16H13N3O2/c20-14(10-11-6-2-1-3-7-11)17-15-12-8-4-5-9-13(12)16(21)19-18-15/h1-9H,10H2,(H,19,21)(H,17,18,20)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432000
PNG
(CHEMBL2348743)
Show SMILES CCCCCC(=O)Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C14H17N3O2/c1-2-3-4-9-12(18)15-13-10-7-5-6-8-11(10)14(19)17-16-13/h5-8H,2-4,9H2,1H3,(H,17,19)(H,15,16,18)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432010
PNG
(CHEMBL2348733)
Show SMILES Nc1n[nH]c(=O)cc1-c1ccccc1
Show InChI InChI=1S/C10H9N3O/c11-10-8(6-9(14)12-13-10)7-4-2-1-3-5-7/h1-6H,(H2,11,13)(H,12,14)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432019
PNG
(CHEMBL2348749)
Show SMILES CCCNc1n[nH]c(=O)cc1-c1ccccc1
Show InChI InChI=1S/C13H15N3O/c1-2-8-14-13-11(9-12(17)15-16-13)10-6-4-3-5-7-10/h3-7,9H,2,8H2,1H3,(H,14,16)(H,15,17)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50431996
PNG
(CHEMBL2348724)
Show SMILES Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C8H7N3O/c9-7-5-3-1-2-4-6(5)8(12)11-10-7/h1-4H,(H2,9,10)(H,11,12)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432004
PNG
(CHEMBL2348739)
Show SMILES Clc1nnc(N(C(=O)Cc2ccccc2)C(=O)Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C24H18ClN3O2/c25-23-19-13-7-8-14-20(19)24(27-26-23)28(21(29)15-17-9-3-1-4-10-17)22(30)16-18-11-5-2-6-12-18/h1-14H,15-16H2
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432007
PNG
(CHEMBL2348736)
Show SMILES Clc1nnc(NC(=O)c2ccccc2)cc1-c1ccccc1
Show InChI InChI=1S/C17H12ClN3O/c18-16-14(12-7-3-1-4-8-12)11-15(20-21-16)19-17(22)13-9-5-2-6-10-13/h1-11H,(H,19,20,22)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432013
PNG
(CHEMBL2348730)
Show SMILES O=c1[nH]nc(NCCN2CCCCC2)c2ccccc12
Show InChI InChI=1S/C15H20N4O/c20-15-13-7-3-2-6-12(13)14(17-18-15)16-8-11-19-9-4-1-5-10-19/h2-3,6-7H,1,4-5,8-11H2,(H,16,17)(H,18,20)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432019
PNG
(CHEMBL2348749)
Show SMILES CCCNc1n[nH]c(=O)cc1-c1ccccc1
Show InChI InChI=1S/C13H15N3O/c1-2-8-14-13-11(9-12(17)15-16-13)10-6-4-3-5-7-10/h3-7,9H,2,8H2,1H3,(H,14,16)(H,15,17)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50431999
PNG
(CHEMBL2348744)
Show SMILES O=C(Cc1ccccc1)Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C16H13N3O2/c20-14(10-11-6-2-1-3-7-11)17-15-12-8-4-5-9-13(12)16(21)19-18-15/h1-9H,10H2,(H,19,21)(H,17,18,20)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432001
PNG
(CHEMBL2348742)
Show SMILES CC(C)C(=O)N(C(=O)C(C)C)c1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C16H19N3O3/c1-9(2)15(21)19(16(22)10(3)4)13-11-7-5-6-8-12(11)14(20)18-17-13/h5-10H,1-4H3,(H,18,20)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432006
PNG
(CHEMBL2348737)
Show SMILES O=C(Nc1cc(-c2ccccc2)c(=O)[nH]n1)c1ccccc1
Show InChI InChI=1S/C17H13N3O2/c21-16(13-9-5-2-6-10-13)18-15-11-14(17(22)20-19-15)12-7-3-1-4-8-12/h1-11H,(H,20,22)(H,18,19,21)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432008
PNG
(CHEMBL2348735)
Show SMILES Nc1cc(-c2ccccc2)c(=O)[nH]n1
Show InChI InChI=1S/C10H9N3O/c11-9-6-8(10(14)13-12-9)7-4-2-1-3-5-7/h1-6H,(H2,11,12)(H,13,14)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432016
PNG
(CHEMBL2348727)
Show SMILES CN1CCC(CC1)Nc1cc(-c2ccccc2)c(=O)[nH]n1
Show InChI InChI=1S/C16H20N4O/c1-20-9-7-13(8-10-20)17-15-11-14(16(21)19-18-15)12-5-3-2-4-6-12/h2-6,11,13H,7-10H2,1H3,(H,17,18)(H,19,21)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50431998
PNG
(CHEMBL2348745)
Show SMILES CC(=O)Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C10H9N3O2/c1-6(14)11-9-7-4-2-3-5-8(7)10(15)13-12-9/h2-5H,1H3,(H,13,15)(H,11,12,14)
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432005
PNG
(CHEMBL2348738)
Show SMILES CCCCCC(=O)N(C(=O)CCCCC)c1nnc(Cl)c2ccccc12
Show InChI InChI=1S/C20H26ClN3O2/c1-3-5-7-13-17(25)24(18(26)14-8-6-4-2)20-16-12-10-9-11-15(16)19(21)22-23-20/h9-12H,3-8,13-14H2,1-2H3
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Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50431995
PNG
(CHEMBL2348725)
Show SMILES O=C(Nc1n[nH]c(=O)c2ccccc12)c1ccccc1
Show InChI InChI=1S/C15H11N3O2/c19-14(10-6-2-1-3-7-10)16-13-11-8-4-5-9-12(11)15(20)18-17-13/h1-9H,(H,18,20)(H,16,17,19)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50431999
PNG
(CHEMBL2348744)
Show SMILES O=C(Cc1ccccc1)Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C16H13N3O2/c20-14(10-11-6-2-1-3-7-11)17-15-12-8-4-5-9-13(12)16(21)19-18-15/h1-9H,10H2,(H,19,21)(H,17,18,20)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432001
PNG
(CHEMBL2348742)
Show SMILES CC(C)C(=O)N(C(=O)C(C)C)c1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C16H19N3O3/c1-9(2)15(21)19(16(22)10(3)4)13-11-7-5-6-8-12(11)14(20)18-17-13/h5-10H,1-4H3,(H,18,20)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432002
PNG
(CHEMBL2348741)
Show SMILES CC(=O)N(C(C)=O)c1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C12H11N3O3/c1-7(16)15(8(2)17)11-9-5-3-4-6-10(9)12(18)14-13-11/h3-6H,1-2H3,(H,14,18)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432011
PNG
(CHEMBL2348732)
Show SMILES CC(=O)Nc1n[nH]c(=O)cc1-c1ccccc1
Show InChI InChI=1S/C12H11N3O2/c1-8(16)13-12-10(7-11(17)14-15-12)9-5-3-2-4-6-9/h2-7H,1H3,(H,14,17)(H,13,15,16)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50431998
PNG
(CHEMBL2348745)
Show SMILES CC(=O)Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C10H9N3O2/c1-6(14)11-9-7-4-2-3-5-8(7)10(15)13-12-9/h2-5H,1H3,(H,13,15)(H,11,12,14)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432002
PNG
(CHEMBL2348741)
Show SMILES CC(=O)N(C(C)=O)c1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C12H11N3O3/c1-7(16)15(8(2)17)11-9-5-3-4-6-10(9)12(18)14-13-11/h3-6H,1-2H3,(H,14,18)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432009
PNG
(CHEMBL2348734)
Show SMILES CC(=O)Nc1cc(-c2ccccc2)c(=O)[nH]n1
Show InChI InChI=1S/C12H11N3O2/c1-8(16)13-11-7-10(12(17)15-14-11)9-5-3-2-4-6-9/h2-7H,1H3,(H,15,17)(H,13,14,16)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432013
PNG
(CHEMBL2348730)
Show SMILES O=c1[nH]nc(NCCN2CCCCC2)c2ccccc12
Show InChI InChI=1S/C15H20N4O/c20-15-13-7-3-2-6-12(13)14(17-18-15)16-8-11-19-9-4-1-5-10-19/h2-3,6-7H,1,4-5,8-11H2,(H,16,17)(H,18,20)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50431992
PNG
(CHEMBL2348748)
Show SMILES CCCNc1cc(-c2ccccc2)c(=O)[nH]n1
Show InChI InChI=1S/C13H15N3O/c1-2-8-14-12-9-11(13(17)16-15-12)10-6-4-3-5-7-10/h3-7,9H,2,8H2,1H3,(H,14,15)(H,16,17)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50431993
PNG
(CHEMBL2348747)
Show SMILES O=c1cc(c(NCc2ccccc2)n[nH]1)-c1ccccc1
Show InChI InChI=1S/C17H15N3O/c21-16-11-15(14-9-5-2-6-10-14)17(20-19-16)18-12-13-7-3-1-4-8-13/h1-11H,12H2,(H,18,20)(H,19,21)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432009
PNG
(CHEMBL2348734)
Show SMILES CC(=O)Nc1cc(-c2ccccc2)c(=O)[nH]n1
Show InChI InChI=1S/C12H11N3O2/c1-8(16)13-11-7-10(12(17)15-14-11)9-5-3-2-4-6-9/h2-7H,1H3,(H,15,17)(H,13,14,16)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432013
PNG
(CHEMBL2348730)
Show SMILES O=c1[nH]nc(NCCN2CCCCC2)c2ccccc12
Show InChI InChI=1S/C15H20N4O/c20-15-13-7-3-2-6-12(13)14(17-18-15)16-8-11-19-9-4-1-5-10-19/h2-3,6-7H,1,4-5,8-11H2,(H,16,17)(H,18,20)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432014
PNG
(CHEMBL2348729)
Show SMILES CCCNc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C11H13N3O/c1-2-7-12-10-8-5-3-4-6-9(8)11(15)14-13-10/h3-6H,2,7H2,1H3,(H,12,13)(H,14,15)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50432015
PNG
(CHEMBL2348728)
Show SMILES O=c1[nH]nc(NCc2ccccc2)c2ccccc12
Show InChI InChI=1S/C15H13N3O/c19-15-13-9-5-4-8-12(13)14(17-18-15)16-10-11-6-2-1-3-7-11/h1-9H,10H2,(H,16,17)(H,18,19)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (human))
BDBM50431993
PNG
(CHEMBL2348747)
Show SMILES O=c1cc(c(NCc2ccccc2)n[nH]1)-c1ccccc1
Show InChI InChI=1S/C17H15N3O/c21-16-11-15(14-9-5-2-6-10-14)17(20-19-16)18-12-13-7-3-1-4-8-13/h1-11H,12H2,(H,18,20)(H,19,21)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432004
PNG
(CHEMBL2348739)
Show SMILES Clc1nnc(N(C(=O)Cc2ccccc2)C(=O)Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C24H18ClN3O2/c25-23-19-13-7-8-14-20(19)24(27-26-23)28(21(29)15-17-9-3-1-4-10-17)22(30)16-18-11-5-2-6-12-18/h1-14H,15-16H2
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432011
PNG
(CHEMBL2348732)
Show SMILES CC(=O)Nc1n[nH]c(=O)cc1-c1ccccc1
Show InChI InChI=1S/C12H11N3O2/c1-8(16)13-12-10(7-11(17)14-15-12)9-5-3-2-4-6-9/h2-7H,1H3,(H,14,17)(H,13,15,16)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Casein kinase I isoform alpha


(Sus scrofa)
BDBM50432012
PNG
(CHEMBL2348731)
Show SMILES CN1CCC(CC1)Nc1n[nH]c(=O)c2ccccc12
Show InChI InChI=1S/C14H18N4O/c1-18-8-6-10(7-9-18)15-13-11-4-2-3-5-12(11)14(19)17-16-13/h2-5,10H,6-9H2,1H3,(H,15,16)(H,17,19)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50432007
PNG
(CHEMBL2348736)
Show SMILES Clc1nnc(NC(=O)c2ccccc2)cc1-c1ccccc1
Show InChI InChI=1S/C17H12ClN3O/c18-16-14(12-7-3-1-4-8-12)11-15(20-21-16)19-17(22)13-9-5-2-6-10-13/h1-11H,(H,19,20,22)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Strasbourg

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...


Bioorg Med Chem Lett 23: 2007-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.027
BindingDB Entry DOI: 10.7270/Q2T1551T
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%