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PubMed code 23518277

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
c-Jun N-terminal kinase 3


(Rattus norvegicus)
BDBM50433094
PNG
(CHEMBL2376915)
Show SMILES Clc1ccccc1Nc1ccc2n(ncc2c1)-c1cccc(c1)C(=O)NCCN1CCOCC1
Show InChI InChI=1S/C26H26ClN5O2/c27-23-6-1-2-7-24(23)30-21-8-9-25-20(16-21)18-29-32(25)22-5-3-4-19(17-22)26(33)28-10-11-31-12-14-34-15-13-31/h1-9,16-18,30H,10-15H2,(H,28,33)
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.10E+3n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of JNK3-mediated c-Jun phosphorylation in rat INS-1 cells after 3 hrs by ELISA


Bioorg Med Chem Lett 23: 2683-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.082
BindingDB Entry DOI: 10.7270/Q21837WC
More data for this
Ligand-Target Pair
c-Jun N-terminal kinase 3


(Rattus norvegicus)
BDBM50433093
PNG
(CHEMBL2376930)
Show SMILES Clc1ccccc1Nc1ccc2n(ncc2c1)-c1cc(ccn1)C(=O)NCCN1CCOCC1
Show InChI InChI=1S/C25H25ClN6O2/c26-21-3-1-2-4-22(21)30-20-5-6-23-19(15-20)17-29-32(23)24-16-18(7-8-27-24)25(33)28-9-10-31-11-13-34-14-12-31/h1-8,15-17,30H,9-14H2,(H,28,33)
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.30E+3n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of JNK3-mediated c-Jun phosphorylation in rat INS-1 cells after 3 hrs by ELISA


Bioorg Med Chem Lett 23: 2683-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.082
BindingDB Entry DOI: 10.7270/Q21837WC
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%