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PubMed code 23611768

Compile data set for download or QSAR
Found 34 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Androgen Receptor


(Homo sapiens (human))
BDBM50434570
PNG
(CHEMBL2386405)
Show SMILES Fc1ccc(cc1)-c1cc(=O)c2c(F)cccc2o1
Show InChI InChI=1S/C15H8F2O2/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8H
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n/an/a 190n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434570
PNG
(CHEMBL2386405)
Show SMILES Fc1ccc(cc1)-c1cc(=O)c2c(F)cccc2o1
Show InChI InChI=1S/C15H8F2O2/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8H
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n/an/a 191n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434569
PNG
(CHEMBL2386396)
Show SMILES Oc1cc(oc2cccc(=O)c12)-c1ccc(cc1)C#N
Show InChI InChI=1S/C16H9NO3/c17-9-10-4-6-11(7-5-10)15-8-13(19)16-12(18)2-1-3-14(16)20-15/h1-8,19H
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n/an/a 250n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434569
PNG
(CHEMBL2386396)
Show SMILES Oc1cc(oc2cccc(=O)c12)-c1ccc(cc1)C#N
Show InChI InChI=1S/C16H9NO3/c17-9-10-4-6-11(7-5-10)15-8-13(19)16-12(18)2-1-3-14(16)20-15/h1-8,19H
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n/an/a 251n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434568
PNG
(CHEMBL2386393)
Show SMILES Oc1cccc2oc(cc(=O)c12)-c1ccc(F)cc1
Show InChI InChI=1S/C15H9FO3/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8,17H
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n/an/a 330n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434568
PNG
(CHEMBL2386393)
Show SMILES Oc1cccc2oc(cc(=O)c12)-c1ccc(F)cc1
Show InChI InChI=1S/C15H9FO3/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8,17H
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n/an/a 331n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434566
PNG
(CHEMBL2386404)
Show SMILES Fc1cccc2oc(cc(=O)c12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C15H8ClFO2/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8H
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n/an/a 360n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434567
PNG
(CHEMBL2386395)
Show SMILES Oc1cc(oc2cccc(=O)c12)-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C15H9NO5/c17-11-2-1-3-13-15(11)12(18)8-14(21-13)9-4-6-10(7-5-9)16(19)20/h1-8,18H
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n/an/a 360n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434566
PNG
(CHEMBL2386404)
Show SMILES Fc1cccc2oc(cc(=O)c12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C15H8ClFO2/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8H
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n/an/a 363n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434567
PNG
(CHEMBL2386395)
Show SMILES Oc1cc(oc2cccc(=O)c12)-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C15H9NO5/c17-11-2-1-3-13-15(11)12(18)8-14(21-13)9-4-6-10(7-5-9)16(19)20/h1-8,18H
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n/an/a 363n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434572
PNG
(CHEMBL274471)
Show SMILES Oc1cc(oc2cccc(=O)c12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C15H9ClO3/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8,18H
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n/an/a 457n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434572
PNG
(CHEMBL274471)
Show SMILES Oc1cc(oc2cccc(=O)c12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C15H9ClO3/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8,18H
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n/an/a 460n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434573
PNG
(CHEMBL2386394)
Show SMILES Fc1cccc2oc(cc(=O)c12)-c1ccccc1
Show InChI InChI=1S/C15H9FO2/c16-11-7-4-8-13-15(11)12(17)9-14(18-13)10-5-2-1-3-6-10/h1-9H
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n/an/a 770n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434573
PNG
(CHEMBL2386394)
Show SMILES Fc1cccc2oc(cc(=O)c12)-c1ccccc1
Show InChI InChI=1S/C15H9FO2/c16-11-7-4-8-13-15(11)12(17)9-14(18-13)10-5-2-1-3-6-10/h1-9H
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n/an/a 776n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50049385
PNG
(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)
Show SMILES Oc1cccc2oc(cc(=O)c12)-c1ccccc1
Show InChI InChI=1S/C15H10O3/c16-11-7-4-8-13-15(11)12(17)9-14(18-13)10-5-2-1-3-6-10/h1-9,16H
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n/an/a 832n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50049385
PNG
(5-Hydroxy-2-phenyl-chromen-4-one | 5-Hydroxyflavon...)
Show SMILES Oc1cccc2oc(cc(=O)c12)-c1ccccc1
Show InChI InChI=1S/C15H10O3/c16-11-7-4-8-13-15(11)12(17)9-14(18-13)10-5-2-1-3-6-10/h1-9,16H
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n/an/a 840n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434574
PNG
(CHEMBL2386397)
Show SMILES CN(C)c1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1
Show InChI InChI=1S/C17H15NO3/c1-18(2)12-8-6-11(7-9-12)16-10-14(20)17-13(19)4-3-5-15(17)21-16/h3-10,20H,1-2H3
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n/an/a 850n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50312650
PNG
(5,4'-dihydroxyflavone | 5-hydroxy-2-(4-hydroxyphen...)
Show SMILES Oc1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1
Show InChI InChI=1S/C15H10O4/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8,16,18H
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n/an/a 851n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434574
PNG
(CHEMBL2386397)
Show SMILES CN(C)c1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1
Show InChI InChI=1S/C17H15NO3/c1-18(2)12-8-6-11(7-9-12)16-10-14(20)17-13(19)4-3-5-15(17)21-16/h3-10,20H,1-2H3
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n/an/a 851n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50312650
PNG
(5,4'-dihydroxyflavone | 5-hydroxy-2-(4-hydroxyphen...)
Show SMILES Oc1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1
Show InChI InChI=1S/C15H10O4/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8,16,18H
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n/an/a 860n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434575
PNG
(CHEMBL2386401)
Show SMILES CSc1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1
Show InChI InChI=1S/C16H12O3S/c1-20-11-7-5-10(6-8-11)15-9-13(18)16-12(17)3-2-4-14(16)19-15/h2-9,18H,1H3
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n/an/a 1.07E+3n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434575
PNG
(CHEMBL2386401)
Show SMILES CSc1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1
Show InChI InChI=1S/C16H12O3S/c1-20-11-7-5-10(6-8-11)15-9-13(18)16-12(17)3-2-4-14(16)19-15/h2-9,18H,1H3
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n/an/a 1.07E+3n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434576
PNG
(CHEMBL2386406)
Show SMILES Fc1cccc2oc(cc(=O)c12)-c1ccc(cc1)C#N
Show InChI InChI=1S/C16H8FNO2/c17-12-2-1-3-14-16(12)13(19)8-15(20-14)11-6-4-10(9-18)5-7-11/h1-8H
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n/an/a 1.20E+3n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434576
PNG
(CHEMBL2386406)
Show SMILES Fc1cccc2oc(cc(=O)c12)-c1ccc(cc1)C#N
Show InChI InChI=1S/C16H8FNO2/c17-12-2-1-3-14-16(12)13(19)8-15(20-14)11-6-4-10(9-18)5-7-11/h1-8H
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n/an/a 1.20E+3n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434577
PNG
(CHEMBL2386392)
Show SMILES Oc1cc(oc2cccc(=O)c12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C16H9F3O3/c17-16(18,19)10-6-4-9(5-7-10)14-8-12(21)15-11(20)2-1-3-13(15)22-14/h1-8,21H
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n/an/a 1.23E+3n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434577
PNG
(CHEMBL2386392)
Show SMILES Oc1cc(oc2cccc(=O)c12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C16H9F3O3/c17-16(18,19)10-6-4-9(5-7-10)14-8-12(21)15-11(20)2-1-3-13(15)22-14/h1-8,21H
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n/an/a 1.24E+3n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434578
PNG
(CHEMBL143978)
Show SMILES COc1cccc2oc(cc(=O)c12)-c1ccc(F)cc1
Show InChI InChI=1S/C16H11FO3/c1-19-13-3-2-4-14-16(13)12(18)9-15(20-14)10-5-7-11(17)8-6-10/h2-9H,1H3
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n/an/a 1.61E+3n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434578
PNG
(CHEMBL143978)
Show SMILES COc1cccc2oc(cc(=O)c12)-c1ccc(F)cc1
Show InChI InChI=1S/C16H11FO3/c1-19-13-3-2-4-14-16(13)12(18)9-15(20-14)10-5-7-11(17)8-6-10/h2-9H,1H3
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n/an/a 1.62E+3n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434579
PNG
(CHEMBL2386399)
Show SMILES Nc1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1
Show InChI InChI=1S/C15H11NO3/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8,18H,16H2
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n/an/a 1.99E+3n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434579
PNG
(CHEMBL2386399)
Show SMILES Nc1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1
Show InChI InChI=1S/C15H11NO3/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8,18H,16H2
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n/an/a 2.00E+3n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434580
PNG
(CHEMBL2386408)
Show SMILES NC(=O)c1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1
Show InChI InChI=1S/C16H11NO4/c17-16(20)10-6-4-9(5-7-10)14-8-12(19)15-11(18)2-1-3-13(15)21-14/h1-8,19H,(H2,17,20)
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n/an/a 3.55E+3n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434580
PNG
(CHEMBL2386408)
Show SMILES NC(=O)c1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1
Show InChI InChI=1S/C16H11NO4/c17-16(20)10-6-4-9(5-7-10)14-8-12(19)15-11(18)2-1-3-13(15)21-14/h1-8,19H,(H2,17,20)
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n/an/a 3.58E+3n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434571
PNG
(CHEMBL16972)
Show SMILES Cc1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1
Show InChI InChI=1S/C16H12O3/c1-10-5-7-11(8-6-10)15-9-13(18)16-12(17)3-2-4-14(16)19-15/h2-9,18H,1H3
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n/an/a 1.11E+4n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (human))
BDBM50434571
PNG
(CHEMBL16972)
Show SMILES Cc1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1
Show InChI InChI=1S/C16H12O3/c1-10-5-7-11(8-6-10)15-9-13(18)16-12(17)3-2-4-14(16)19-15/h2-9,18H,1H3
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n/an/a 1.12E+4n/an/an/an/an/an/a



Meijo University

Curated by ChEMBL


Assay Description
Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay


Bioorg Med Chem 21: 2968-74 (2013)


Article DOI: 10.1016/j.bmc.2013.03.060
BindingDB Entry DOI: 10.7270/Q2FT8NFN
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%