Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA methyltransferase 1 (RFTS-lacking Dnmt1) (Homo sapiens (Human)) | BDBM50384789![]() (CHEMBL2037378 | Laccaic acid A (LCA)) | PDB GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa | Assay Description Assays (0.1 ml) were conducted in 96-well black half-area plates in either a Wallac VICTOR2 or Biotek Synergy Neo plate reader at 37 °C in 10 mM Tri... | J Biol Chem 288: 23858-67 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA methyltransferase 1 (RFTS-lacking Dnmt1) (Homo sapiens (Human)) | BDBM50430056![]() (CHEMBL2336409 | SGI-1027) | PDB GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa | Assay Description Assays (0.1 ml) were conducted in 96-well black half-area plates in either a Wallac VICTOR2 or Biotek Synergy Neo plate reader at 37 °C in 10 mM Tri... | J Biol Chem 288: 23858-67 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA methyltransferase 1 (RTFS-containing Dnmt1) (Homo sapiens (Human)) | BDBM50384789![]() (CHEMBL2037378 | Laccaic acid A (LCA)) | PDB GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 1.91E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa | Assay Description Assays (0.1 ml) were conducted in 96-well black half-area plates in either a Wallac VICTOR2 or Biotek Synergy Neo plate reader at 37 °C in 10 mM Tri... | J Biol Chem 288: 23858-67 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA methyltransferase 1 (RFTS-lacking Dnmt1) (Homo sapiens (Human)) | BDBM50384789![]() (CHEMBL2037378 | Laccaic acid A (LCA)) | PDB GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa | Assay Description Assays (0.1 ml) were conducted in 96-well black half-area plates in either a Wallac VICTOR2 or Biotek Synergy Neo plate reader at 37 °C in 10 mM Tri... | J Biol Chem 288: 23858-67 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA methyltransferase 3a (Dnmt3a) (Homo sapiens (Human)) | BDBM50384789![]() (CHEMBL2037378 | Laccaic acid A (LCA)) | PDB GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 5.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa | Assay Description Assays (0.1 ml) were conducted in 96-well black half-area plates in either a Wallac VICTOR2 or Biotek Synergy Neo plate reader at 37 °C in 10 mM Tri... | J Biol Chem 288: 23858-67 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
M.SssI methyltransferase (Spiroplasma monobiae strain MQ-1) | BDBM50384789![]() (CHEMBL2037378 | Laccaic acid A (LCA)) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 5.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa | Assay Description Assays (0.1 ml) were conducted in 96-well black half-area plates in either a Wallac VICTOR2 or Biotek Synergy Neo plate reader at 37 °C in 10 mM Tri... | J Biol Chem 288: 23858-67 (2013) | |||||||||||
More data for this Ligand-Target Pair |