Affinity Data by PubMed id=23839987

PubMed code 23839987

Found 6 hits of Enzyme Inhibition Constant Data
Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
DNA methyltransferase 1 (RFTS-lacking Dnmt1) (Homo sapiens (Human))	BDBM50384789 (CHEMBL2037378 \| Laccaic acid A (LCA)) Show SMILES Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
University of Iowa					Assay Description Assays (0.1 ml) were conducted in 96-well black half-area plates in either a Wallac VICTOR2 or Biotek Synergy Neo plate reader at 37 °C in 10 mM Tri...				J Biol Chem 288: 23858-67 (2013)
University of Iowa					More data for this Ligand-Target Pair
DNA methyltransferase 1 (RFTS-lacking Dnmt1) (Homo sapiens (Human))	BDBM50430056 (CHEMBL2336409 \| SGI-1027) Show SMILES Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Iowa					Assay Description Assays (0.1 ml) were conducted in 96-well black half-area plates in either a Wallac VICTOR2 or Biotek Synergy Neo plate reader at 37 °C in 10 mM Tri...				J Biol Chem 288: 23858-67 (2013)
University of Iowa					More data for this Ligand-Target Pair
DNA methyltransferase 1 (RTFS-containing Dnmt1) (Homo sapiens (Human))	BDBM50384789 (CHEMBL2037378 \| Laccaic acid A (LCA)) Show SMILES Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet	Article PubMed	n/a	n/a	1.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Iowa					Assay Description Assays (0.1 ml) were conducted in 96-well black half-area plates in either a Wallac VICTOR2 or Biotek Synergy Neo plate reader at 37 °C in 10 mM Tri...				J Biol Chem 288: 23858-67 (2013)
University of Iowa					More data for this Ligand-Target Pair
DNA methyltransferase 1 (RFTS-lacking Dnmt1) (Homo sapiens (Human))	BDBM50384789 (CHEMBL2037378 \| Laccaic acid A (LCA)) Show SMILES Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet	Article PubMed	n/a	n/a	2.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Iowa					Assay Description Assays (0.1 ml) were conducted in 96-well black half-area plates in either a Wallac VICTOR2 or Biotek Synergy Neo plate reader at 37 °C in 10 mM Tri...				J Biol Chem 288: 23858-67 (2013)
University of Iowa					More data for this Ligand-Target Pair
DNA methyltransferase 3a (Dnmt3a) (Homo sapiens (Human))	BDBM50384789 (CHEMBL2037378 \| Laccaic acid A (LCA)) Show SMILES Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet	Article PubMed	n/a	n/a	5.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Iowa					Assay Description Assays (0.1 ml) were conducted in 96-well black half-area plates in either a Wallac VICTOR2 or Biotek Synergy Neo plate reader at 37 °C in 10 mM Tri...				J Biol Chem 288: 23858-67 (2013)
University of Iowa					More data for this Ligand-Target Pair
M.SssI methyltransferase (Spiroplasma monobiae strain MQ-1)	BDBM50384789 (CHEMBL2037378 \| Laccaic acid A (LCA)) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars AffyNet	Article PubMed	n/a	n/a	5.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Iowa					Assay Description Assays (0.1 ml) were conducted in 96-well black half-area plates in either a Wallac VICTOR2 or Biotek Synergy Neo plate reader at 37 °C in 10 mM Tri...				J Biol Chem 288: 23858-67 (2013)
University of Iowa					More data for this Ligand-Target Pair

* indicates data uncertainty>20%