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PubMed code 24157369

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 4 (5-HT4) receptor


(Sus scrofa)
BDBM50448450
PNG
(CHEMBL3126112)
Show SMILES CN1CCC(COC(=O)c2cc(Cl)c(N)c3OCCOc23)CC1
Show InChI InChI=1S/C16H21ClN2O4/c1-19-4-2-10(3-5-19)9-23-16(20)11-8-12(17)13(18)15-14(11)21-6-7-22-15/h8,10H,2-7,9,18H2,1H3
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PC sid
UniChem

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Article
PubMed
n/an/an/a 0.0800n/an/an/an/an/a



Molecular NeuroImaging LLC

Curated by ChEMBL


Assay Description
Binding affinity to 5HT4 receptor in pig striatal membranes


Bioorg Med Chem Lett 23: 6243-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.097
BindingDB Entry DOI: 10.7270/Q2RJ4KZ2
More data for this
Ligand-Target Pair
HTR4


(GUINEA PIG)
BDBM82505
PNG
(CAS_121881 | NSC_121881 | SB204070)
Show SMILES CCCCN1CCC(COC(=O)c2cc(Cl)c(N)c3OCCOc23)CC1
Show InChI InChI=1S/C19H27ClN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/an/a 0.0200n/an/an/an/an/a



Molecular NeuroImaging LLC

Curated by ChEMBL


Assay Description
Binding affinity to 5HT4 receptor in guinea pig distal colon


Bioorg Med Chem Lett 23: 6243-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.097
BindingDB Entry DOI: 10.7270/Q2RJ4KZ2
More data for this
Ligand-Target Pair
Serotonin 4 (5-HT4) receptor


(Sus scrofa)
BDBM50327858
PNG
((1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-d...)
Show SMILES CCCCN1CCC(COC(=O)c2cc(I)c(N)c3OCCOc23)CC1
Show InChI InChI=1S/C19H27IN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/a 0.0800n/an/an/an/an/a



Molecular NeuroImaging LLC

Curated by ChEMBL


Assay Description
Binding affinity to 5HT4 receptor in pig striatal membranes


Bioorg Med Chem Lett 23: 6243-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.097
BindingDB Entry DOI: 10.7270/Q2RJ4KZ2
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%